• By first using our newly proposed PCSC framework for spatial localization at the frame-level and then applying it for temporal segmentation at the tube-level, the action localization results are progressively improved at both the frame level and the video level. Comprehensive experiments demonstrate the effectiveness of our new approaches.Face…[Read more]

  • aucoma was most prevalent. Genetic diagnoses ascertained in 24.7% of probands supported clinical diagnoses and genetic counseling. International collaborative efforts are required to identify further genes because the majority of individuals still lack a clear molecular diagnosis.

    We report on the largest cohort of individuals with childhood…[Read more]

  • Trichlorfon is widely used to control pest insects and various parasitic infestations in agriculture, aquaculture and human medicine. However, the long-term widespread use and overuse of trichlorfon poses risks to public and environmental health. Thus, the aim of this study was to evaluate the interference of trichlorfon on gene transcription…[Read more]

  • Infection with hepatitis C virus (HCV) remains a major cause of morbidity and mortality worldwide despite the recent advent of highly effective direct-acting antivirals. The envelope glycoproteins of HCV are heavily glycosylated with a high proportion of high-mannose glycans (HMGs), which serve as a shield against neutralizing antibodies and…[Read more]

  • In densely populated areas with insufficient protection measures, the virus spreads freely, thus increasing the likelihood of generating escape mutants. India and Manaus exemplify this situation. Natural evolution selects the mutants that multiply most efficiently without eliminating the host, thus facilitating their spread. Contrastingly, the…[Read more]

  • Melting of snow and glaciers from the high-altitude Himalayan region is a significant water source to the major Himalayan rivers, especially in the upper Indus Basin (UIB), which contributes up to 70% of river discharge. Considering Indus Basin as a largest irrigation system dependent on snow and glacier melt runoff, it is imperative to study the…[Read more]

  • Additional studies will have to be carried out to determine whether this unique inhibition mechanism can occur at the cell surface.Competitive inhibitors of galactocerebrosidase (GALC) could be candidates for pharmacological chaperone therapy of patients with Krabbe disease. The known and selective nortropane-type iminosugar galacto-noeurostegine…[Read more]

  • Unexpectedly, Giemsa staining showed an increase in the rate of apoptosis in infected cells.

    Regulated genes after infection are involved in many different biological pathways and various components of the cell. This suggests that the parasite uses highly sophisticated ways to maintain the viability of the cell.

    Regulated genes after…[Read more]

  • Due to the rich vitamin content in citrus fruit, citrus is an important crop around the world. However, the yield of these citrus crops is often reduced due to the damage of various pests and diseases. In order to mitigate these problems, several convolutional neural networks were applied to detect them. It is of note that the performance of these…[Read more]

  • The coronavirus disease of 2019 (COVID-19) represents a difficult challenge and could have devastating consequences for the healthcare system and healthcare workers in war-torn countries with poor healthcare facilities such as Yemen. Our study aimed to evaluate the knowledge, preparedness, counselling practices of healthcare workers regarding…[Read more]

  • A multifaceted strategic approach can help increase UIM physician participation in graduate training programs, helping address health equity.New Mexico has the largest number of former uranium workers, mostly racial/ethnic minorities. Uranium workers are at risk for dyspnea secondary to mine dust exposure. The association between dyspnea and…[Read more]

  • In this paper we report on the influence of polysaccharides’ molecular structure on the antibacterial activity and cytotoxicity of composites based on silver nanoparticles (AgNPs) immobilized into carboxymethyl-cellulose (CMC). These composites were green synthesized from the reduction of silver ions into aqueous solutions of the polysaccharide,…[Read more]

  • Here we review recent progress in cooling micro-/nanoelectronic devices significantly below 10 mK. A number of groups worldwide are working to produce sub-millikelvin on-chip electron temperatures, motivated by the possibility of observing new physical effects and improving the performance of quantum technologies, sensors and metrological…[Read more]

  • Polycystic ovary syndrome (PCOS) is associated with gut microbiota disturbance. Emerging evidence has shown that gut microbiota plays a major role in the development of PCOS. To better understand how the gut microbiota contributes to the development of PCOS, we investigated the influences of high-fat diet and hyperandrogenism, independently or…[Read more]

  • Volume holographic phase gratings possessing the saturated refractive index modulation amplitudes as large as 4.5×10-2 were recorded at a wavelength of 532 nm in a photopolymerizable nanoparticle-polymer composite (NPC) film dispersed with ultrahigh refractive index hyperbranched-polymer (HBP) organic nanoparticles. This prominent result was…[Read more]

  • The use of nanotechnology for administering drugs is a recent development that presents promising results. Therapeutic Pulsed Ultrasound (TPU) is one such therapeutic option and is widely used for treating soft tissue lesions. Thus, the objective of this study was to investigate the therapeutic effect of phonophoresis using diclofenac (DC) linked…[Read more]

  • Stochastic separation theorems play important roles in high-dimensional data analysis and machine learning. It turns out that in high dimensional space, any point of a random set of points can be separated from other points by a hyperplane with high probability, even if the number of points is exponential in terms of dimensions. This and similar…[Read more]

  • The here shown data support the article “The Sand Equation and its Enormous Practical Relevance for Solid-State Lithium Metal Batteries”. In this data set, all cells include the poly (ethylene oxide)-based solid polymer electrolyte (PEO-based SPE). The behaviour in symmetric Li||Li cells are provided in a three-electrode cell setup, thus with the…[Read more]

  • Rush Leth posted an update 7 months, 4 weeks ago

    Our results indicate that an acidic environment is essential for CARDS toxin retrograde transport to endoplasmic reticulum. Moreover, retrograde transport facilitates toxin clipping and is required to induce vacuole formation. Additionally, toxin-mediated cell vacuolation is strictly dependent on the function of vacuolar type-ATPase.The shift in…[Read more]

  • There has also been a growing appreciation of the physical properties conferred upon many of these proteins by regions of each polypeptide that are of low primary sequence complexity and that are often intrinsically disordered. This peculiar feature of a surprisingly large number of proteins enables a disordered region of the protein to morph into…[Read more]

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