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Valentin Napier posted an update 9 months, 2 weeks ago
losses, and lower major Cobb correction versus AIS patients.Morphea, also known as localized scleroderma, is an uncommon idiopathic inflammatory disorder leading to the development of sclerotic plaques in the skin. The disorder preferentially affects females. The pathogenesis of morphea is not well-understood. The disorder is likely to have an…[Read more]
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Karstensen Bonde posted an update 9 months, 2 weeks ago
Reduction of a tricobalt(II) tri(bromide) cluster supported by a tris(β-diketiminate) cyclophane results in halide loss, ligand compression, and metal-metal bond formation to yield a 48-electron CoI3 cluster, Co3LEt/Me (2). Upon reaction of 2 with dinitrogen, all metal-metal bonds are broken, steric conflicts are relaxed, and dinitrogen is…[Read more]
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Bradford Swanson posted an update 9 months, 2 weeks ago
STRATION Brazilian Registry of Clinical Trials (ReBEC) ID RBR-9rf33n, date of registration 17 May 2018.BACKGROUND Primary dysmenorrhoea (PDM) is defined as a series of pain-dominated symptoms during and after menstruation without organic lesions. Nonsteroidal anti-inflammatory drugs and oral contraceptives are usually recommended as first-line…[Read more]
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Rosendal Terkildsen posted an update 9 months, 2 weeks ago
Introduction The histological composition of the clot influences its mechanical properties, affects the efficacy of endovascular treatment (EVT), and could determine the clinical outcome of patients with acute ischemic stroke (AIS). Insights into clot composition may guide therapeutic decision-making prior to EVT and facilitate revascularization…[Read more]
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Lindberg Todd posted an update 9 months, 2 weeks ago
The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a pandemic that has been associated with over 700,000 deaths as of 5th August 2020. Research is ongoing around the world to create vaccines and therapies to minimise rates of disease spread and mortality. Crucial to these efforts are molecular characterisations of…[Read more]
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Mathiassen Herring posted an update 9 months, 2 weeks ago
We found that survival outcomes did not change following the implementation of a “restrictive” transfusion policy. There was also a decrease in the extracorporeal blood flow rates with restrictive transfusion of 0.5 L/min. Nonsurvivors of venovenous extracorporeal membrane oxygenation had higher usage of RBC units following a change in t…[Read more]
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Chase Brennan posted an update 9 months, 2 weeks ago
To determine the factors influencing functional improvement of cervical spinal cord injuries during hospital admission.
We performed a retrospective study of patients with an acute cervical spinal cord injury who had completed a rehabilitation programme in the Spinal Cord Injuries Unit of the Canary Islands between 2001 and 2018. To…[Read more]
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Elgaard Baird posted an update 9 months, 2 weeks ago
By responding to environmental and intracellular stimuli, ion channels play critical roles in sperm function regulation. Although the importance of ion channel in male reproduction has drawn increasing attention in many species, the knowledge about ion channels in zebrafish sperm is limited. Here, we show zebrafish sperm motility could be…[Read more]
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Pehrson Kendall posted an update 9 months, 2 weeks ago
Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]
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Gillespie Baird posted an update 9 months, 2 weeks ago
Mutations of SOX10 result in a broad range of phenotypes including Waardenburg syndrome (WS types 2 and 4) that can be found in association with peripheral demyelinating neuropathy and/or central dysmyelinating leukodystrophy. Here, we generated induced pluripotent stem cells (iPSCs) from a patient carrying a de novo heterozygous missense mutation…[Read more]
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Odgaard Hammer posted an update 9 months, 2 weeks ago
3, n = 6). There was an even larger lasting benefit when pain or pressure symptoms were analysed in isolation.
This study adds to the evidence of technique safety and feasibility. The procedure resulted in a significant long-term improvement in symptoms.
This study adds to the evidence of technique safety and feasibility. The procedure…[Read more]
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Lindberg Boyd posted an update 9 months, 2 weeks ago
Arthrodesis of the first tarsometatarsal joint (TMT1) reduces pathologic angles at the anatomic center of rotation of angulation and presents a substantial correction potential in 3 planes in the treatment of hallux abductovalgus. The optimal fixation method remains unclear since prevailing dorsomedial locking plates and/or compression screws…[Read more]
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Rask Dotson posted an update 9 months, 2 weeks ago
By first using our newly proposed PCSC framework for spatial localization at the frame-level and then applying it for temporal segmentation at the tube-level, the action localization results are progressively improved at both the frame level and the video level. Comprehensive experiments demonstrate the effectiveness of our new approaches.Face…[Read more]
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Woodruff Gravgaard posted an update 9 months, 2 weeks ago
aucoma was most prevalent. Genetic diagnoses ascertained in 24.7% of probands supported clinical diagnoses and genetic counseling. International collaborative efforts are required to identify further genes because the majority of individuals still lack a clear molecular diagnosis.
We report on the largest cohort of individuals with childhood…[Read more]
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Snow Charles posted an update 9 months, 2 weeks ago
Trichlorfon is widely used to control pest insects and various parasitic infestations in agriculture, aquaculture and human medicine. However, the long-term widespread use and overuse of trichlorfon poses risks to public and environmental health. Thus, the aim of this study was to evaluate the interference of trichlorfon on gene transcription…[Read more]
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Durham Todd posted an update 9 months, 2 weeks ago
Infection with hepatitis C virus (HCV) remains a major cause of morbidity and mortality worldwide despite the recent advent of highly effective direct-acting antivirals. The envelope glycoproteins of HCV are heavily glycosylated with a high proportion of high-mannose glycans (HMGs), which serve as a shield against neutralizing antibodies and…[Read more]
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McKee Wood posted an update 9 months, 2 weeks ago
In densely populated areas with insufficient protection measures, the virus spreads freely, thus increasing the likelihood of generating escape mutants. India and Manaus exemplify this situation. Natural evolution selects the mutants that multiply most efficiently without eliminating the host, thus facilitating their spread. Contrastingly, the…[Read more]
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Williamson Giles posted an update 9 months, 2 weeks ago
Melting of snow and glaciers from the high-altitude Himalayan region is a significant water source to the major Himalayan rivers, especially in the upper Indus Basin (UIB), which contributes up to 70% of river discharge. Considering Indus Basin as a largest irrigation system dependent on snow and glacier melt runoff, it is imperative to study the…[Read more]
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Corcoran Hardison posted an update 9 months, 2 weeks ago
Additional studies will have to be carried out to determine whether this unique inhibition mechanism can occur at the cell surface.Competitive inhibitors of galactocerebrosidase (GALC) could be candidates for pharmacological chaperone therapy of patients with Krabbe disease. The known and selective nortropane-type iminosugar galacto-noeurostegine…[Read more]
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Husum Birch posted an update 9 months, 2 weeks ago
Unexpectedly, Giemsa staining showed an increase in the rate of apoptosis in infected cells.
Regulated genes after infection are involved in many different biological pathways and various components of the cell. This suggests that the parasite uses highly sophisticated ways to maintain the viability of the cell.
Regulated genes after…[Read more]
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