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Beach Tobiasen posted an update 9 months, 2 weeks ago
SUMMARY Prenatal diagnostic genetic testing through amniocentesis or chorionic villus sampling can be offered to every patient who wants to learn genetic information about their fetus. Cytogenetic testing, such as microarray is a first tier test to assess cause for these conditions and can provide meaningful answers. When a gastrointestinal…[Read more]
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Whitehead Pape posted an update 9 months, 2 weeks ago
o maximize coverage and intake adherence in programs using SQ-LNS.
The enhanced IYCF-SQ-LNS intervention using the existing health care delivery platform was associated with a reduction in prevalence of anemia and improvement in mean hemoglobin. At endline among the subpopulation receiving ≥3 mo of SQ-LNS, their LAZ, WAZ, and hemoglobin i…[Read more]
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Salas Winkler posted an update 9 months, 2 weeks ago
An amendment to this paper has been published and can be accessed via a link at the top of the paper.A hospital-based cross-sectional study in SIGES project was conducted during 2016.5-2017.5 in West China Hospital. It was aimed to observe the prevalence of atrophic gastritis (AG) in southwest China, and assess the diagnostic strength of serum…[Read more]
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Lindberg Todd posted an update 9 months, 2 weeks ago
The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a pandemic that has been associated with over 700,000 deaths as of 5th August 2020. Research is ongoing around the world to create vaccines and therapies to minimise rates of disease spread and mortality. Crucial to these efforts are molecular characterisations of…[Read more]
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Konradsen Mccormick posted an update 9 months, 2 weeks ago
Iron is an essential component for growth and development. Despite relative abundance in the environment, bioavailability of iron is limited due to oxidation by atmospheric oxygen into insoluble ferric iron. Filamentous fungi have developed diverse pathways to uptake and use iron. In the current study, a putative iron utilization gene cluster…[Read more]
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Sonne Lu posted an update 9 months, 2 weeks ago
Background Great advances have been made for the treatment of urothelial carcinoma by the introduction of checkpoint inhibitors (CPI). Single-agent immunotherapy with CPIs has been approved for patients with metastatic or locally advanced inoperable urothelial carcinoma who have either progressed during or after platinum-based chemotherapy or who…[Read more]
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Mcgowan Meadows posted an update 9 months, 2 weeks ago
We found that taking SG significantly reduced the depressive symptoms assessed by HAMD-24 and improved cognitive functions assessed by MoCA in PSD patients. Furthermore, at baseline, PSD patients showed decreased dALFF in the right precuneus and increased dFC between the right precuneus and left angular gyrus, compared with HC. After intervention,…[Read more]
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Svenningsen Griffith posted an update 9 months, 2 weeks ago
Spinal high mobility group box 1 protein (HMGB1) plays crucial roles in arthritis-induced pain; however, the involvement of peripheral HMGB1 has not been examined previously. In this study, we addressed the role of peripheral HMGB1 and explored if sex contributes differentially to nociception in arthritis. We found Hmgb1 expression to be elevated…[Read more]
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Olsen Gillespie posted an update 9 months, 2 weeks ago
Human carbonic anhydrase IX (hCA IX) is a promising target for the development of potential anticancer agents. In the current study, pharmacophore and 3D-QSAR models have been developed using SLC-0111 derivatives. The developed models have been further utilized for the virtual screening process to develop potent hCA IX inhibitors. Thirteen…[Read more]
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Faber Connell posted an update 9 months, 2 weeks ago
Compared with the 9 h group, the mRNA and protein expression of HO-1 were increased in dose-dependent manner in the 3 μM RES, 10 μM RES and 30 μM RES group. Compared with the 9 h group, rat myocardial injury was gradually alleviated in 3 μM RES, 10 μM RES and 30 μM RES groups. However, the rat myocardial injury in the 100 μM RES group showed…[Read more]
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Korsholm Peck posted an update 9 months, 2 weeks ago
Purpose Imaging-based metrics for analysis of biological tissues are powerful tools that can extract information such as shape, size, periodicity, and many other features to assess the requested qualities of a tissue. Muscular and osseous tissues consist of periodic structures that are directly related to their function, and so analysis of these…[Read more]
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Pehrson Kendall posted an update 9 months, 2 weeks ago
Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]
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Corcoran Hardison posted an update 9 months, 2 weeks ago
Additional studies will have to be carried out to determine whether this unique inhibition mechanism can occur at the cell surface.Competitive inhibitors of galactocerebrosidase (GALC) could be candidates for pharmacological chaperone therapy of patients with Krabbe disease. The known and selective nortropane-type iminosugar galacto-noeurostegine…[Read more]
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Ellis White posted an update 9 months, 2 weeks ago
The complete mitochondrial genome sequence of the Icefish, Chionobathyscus dewitti was determined by the Next Generation Sequencing (NGS) analysis. The complete mitogenome was 17,452 bp in length, which encoded the canonical 13 protein-coding genes, 22 tRNAs, two rRNAs, and two non-coding regions. As shown in the other notothenids, translocation o…[Read more]
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Kinney Berthelsen posted an update 9 months, 2 weeks ago
t of age-associated changes to immunity.A combination of decision tree (DT) and fuzzy logic techniques was used to develop a fuzzy model for differentiating peanut plant from weeds. Color features and wavelet-based texture features were extracted from images of peanut plant and its three common weeds. Two feature selection techniques namely…[Read more]
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Skov Mclean posted an update 9 months, 2 weeks ago
Lesions were classified as stiff in 91 cases and soft in 35 (kappa coefficient=0.932). The ratio of stiff to soft lesions was significantly higher in PC than in non-PC (623 vs. 2932, P<0.001). The sensitivity, specificity, and negative predictive value of a stiff lesion with vs. without MPDD for diagnosis of PC were 94%, 23%, and 50% vs. 100%,…[Read more]
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Rouse Lu posted an update 9 months, 2 weeks ago
Bone imbalance between anabolic and catabolic processes at the level of remodeling unit due to the prevalence of resorbing activity, represents a health problem of aging. The consequence is the negative balance of bone turnover that can lead to osteoporosis. Physical activity (PA) can play a central role in the comprehensive management of…[Read more]
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Mays Silver posted an update 9 months, 2 weeks ago
Two rounds of literature review using a three-step method will be performed. Risk of Bias assessment will be performed using Covidence, and quality assessment of selected articles will be done using the Critical Appraisal Skills Programme (CASP) checklist.
The results of the systematic review will consider the reported context in which…[Read more]
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Kondrup Pihl posted an update 9 months, 2 weeks ago
The results of this study demonstrated a sedentary lifestyle in young adults during the COVID-19 pandemic, which will assist health policymakers and practitioners in the development of population specific health education and behavior interventions during this pandemic and for other future events.Wound healing constitutes an essential process for…[Read more]
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Randall Guy posted an update 9 months, 2 weeks ago
Due to the rich vitamin content in citrus fruit, citrus is an important crop around the world. However, the yield of these citrus crops is often reduced due to the damage of various pests and diseases. In order to mitigate these problems, several convolutional neural networks were applied to detect them. It is of note that the performance of these…[Read more]
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