• McHugh Damsgaard posted an update 8 months ago

    The metabolic fluxes in each of the strains producing resveratrol were successfully investigated by 13C metabolic flux analysis. The results showed that the balance between the citric acid cycle and the malonyl-CoA supply node was important for resveratrol production.We present a computational study of the electronic structure and lattice dynamics…[Read more]

  • Jones Parks posted an update 8 months ago

    Allogeneic hematopoietic stem cell transplantation (alloHSCT) reduced the relapse risk of IHR patients (3-year RFS alloHSCT 40.0±12.8% vs. chemotherapy 8.6±5.8%, P= 0.010). The prediction model can help identify patients with an unfavorable prognosis and refine risk-adapted therapy for intermediate risk AML patients.Gastric cancer is one of the m…[Read more]

  • Durham Estes posted an update 8 months ago

    By reducing the cerebral blood flow and thereby increasing the resting deoxyhaemoglobin concentration, many human studies have shown that caffeine has a beneficial effect on enhancing the magnitude of blood-oxygenation-level-dependent (BOLD) responses. However, the effect of caffeine on BOLD responses in animals under anaesthesia has not been…[Read more]

  • Lindberg Holst posted an update 8 months ago

    Cardiac glycosides inhibit Na

    /K

    -ATPase and are used to treat heart failure and arrhythmias. They can induce inflammasome activation and pyroptosis in macrophages, suggesting cytotoxicity, which remains to be elucidated in human tissues.

    To determine the cell-type specificity of this cytotoxicity, we used human monocyte-derived…[Read more]

  • Vick Lee posted an update 8 months ago

    Cowpea (Vigna unguiculata (L.) Walp) is an important multipurpose legume crop grown in arid and semi-arid areas of sub-Saharan Africa. The crop associates with a wide diversity of high ecological value rhizobia bacteria, improving biological soil fertility and crop production. Here, we evaluated the symbiotic efficiency (SE) and genetic diversity…[Read more]

  • Moses Winkel posted an update 8 months ago

    rrence after D2 gastrectomy.The basal ganglia (BG) are involved in cognitive/motivational functions in addition to movement control. Thus, BG segregated circuits, the sensorimotor (SM) and medial prefrontal (mPF) circuits, process different functional domains, such as motor and cognitive/motivational behaviours, respectively. With a high presence…[Read more]

  • Travis Smedegaard posted an update 8 months ago

    Obtaining an arteriovenous (AV) access for initiation of hemodialysis is considered the gold standard as it reduces risks of infections, hospitalizations, and need for interventions. It is well documented that creation of AV access can cause or aggravate heart failure. Once AV access is created, blood volume, cardiac contractility, and left…[Read more]

  • Boesen Wilkins posted an update 8 months ago

    The binding interactions of bioactive compounds with proteins are of great importance in the food, biochemistry and pharmaceutical fields. Herein, the binding mechanisms between 5-O-caffeoylquinic acid (5-CQA) and ovalbumin (OVA) were investigated by multi-spectroscopic studies combined with docking and molecular dynamics (MD) simulations. The…[Read more]

  • Egan Hewitt posted an update 8 months ago

    As far as the authors know, this is the first study to present a visual representation of the complex relationship between factors influencing the delivery of cancer care pathways.

    As far as the authors know, this is the first study to present a visual representation of the complex relationship between factors influencing the delivery of cancer…[Read more]

  • Skaarup Shelton posted an update 8 months ago

    1% to 6.1%], using 450-ml glasses was 1.0% higher (95% CI = -9.1 to 12.2) and using 510-ml glasses was 0.4% lower (95% CI = -9.4 to 9.4). For restaurants, compared with 300-ml glasses, the volume of wine sold using 250-ml glasses did not show a significant difference 9.6% lower (95% CI = -19.0 to 0.7). Using 370-ml glasses the volume of wine sold…[Read more]

  • Junker Carr posted an update 8 months ago

    is a medium-sized leguminous plant found widely in tropical to subtropical areas. It has been used as a medicinal ingredient and in rodenticides by local communities in both Indonesia and the Philippines. This study aimed to investigate the wound healing effects of an ointment containing

    leaves on inflammatory cells using a rat model. We also…[Read more]

  • Napier Gregersen posted an update 8 months ago

    This scoping review focuses on the assessment of commensality in research and attempts to identify used methods for performing research on commensality. It reflects a multidisciplinary research field and draws on findings from Web of Science Core Collection, up to April 2019. The empirical material consisted of 61 studies, whereof most were…[Read more]

  • Lehmann Stevenson posted an update 8 months ago

    This study evaluated parasitism and predation on sentinel egg masses of three stink bug species, the spined soldier bug, Podisus maculiventris (Say), the brown stink bug, Euschistus servus (Say), and the invasive brown marmorated stink bug (BMSB), Halyomorpha halys (Stål), in ornamental landscapes composed of either native or exotic plants. This…[Read more]

  • Fletcher Hassan posted an update 8 months ago

    INTRODUCTION 3,4-dihydroxy-6-fluoro-L-phenylalanine (FDOPA) uptake quantification in glioma assessment can be distorted using a non-optimal time frame binning of time-activity curves (TAC). Under-sampling or over-sampling dynamic PET images induces significant variations on kinetic parameters quantification. We aimed to optimize temporal time…[Read more]

  • Slater Garner posted an update 8 months ago

    Meiotic recombination enables reciprocal exchange of genetic information between parental chromosomes and is essential for fertility. MEIOB, a meiosis-specific ssDNA-binding protein, regulates early meiotic recombination. click here Here we report that the human infertility-associated missense mutation (N64I) in MEIOB causes protein degradation…[Read more]

  • Jain Salomonsen posted an update 8 months ago

    Autonomous production of adrenocorticotropic hormone (ACTH) from pituitary corticotroph adenomas is the primary cause of Cushing’s disease. Somatostatin receptor, a G protein-coupled receptor (GPCR), types 2 (SSTR2) and 5 (SSTR5) mRNA expression is greater than that of other SSTR subtypes in human corticotroph adenomas. Further, the multiligand…[Read more]

  • Slater Sheehan posted an update 8 months ago

    Palmo-plantar lesions in discoid lupus erythematosus (DLE) can be considered a very distinct rarity, generally refractory to conventional treatments. We present a 47-year-old African female patient with a 6-month clinical history of palm and soles erosions. Clinical examination revealed painful multiple, well defined, erosions with an erythematous…[Read more]

  • Martinez Leblanc posted an update 8 months ago

    6% of the overall cohort. On univariate analysis, only in-state location, distance to the hospital, and WHO grade were associated with enrollment at initial diagnosis and recurrence. Minority status, insurance type, median household income, and percent below poverty were not associated with clinical trial enrollment. CONCLUSION Minority and…[Read more]

  • List Hogan posted an update 8 months ago

    Patient-reported satisfaction scores, including the Press Ganey surveys, are increasingly used as measures for quality healthcare among surgical subspecialties. However, the influence of surgeon sociodemographics is not clear.

    This cross-sectional study analyzed Press Ganey surveys linked to outpatient surgical visits at a single academic…[Read more]

  • Sonne Bengtsen posted an update 8 months ago

    Background The growing move towards personalised health and social care systems means that every effort needs to be made to generate patient-reported outcome data. However, the deteriorating nature of dementia can make it difficult for people with dementia to complete self-reported questionnaires and it is often necessary to rely on a family…[Read more]

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