-
Archer Salazar posted an update 8 months ago
A novel magnetic borate-functionalized metal-organic framework nanocomposite was designed and fabricated for selective enrichment of catecholamines from human urine. Firstly, the polytannic acid (PTA) layer with natural low-cost and ecofriendly polyphenol tannic acid as the organic ligand and Fe3+ as the cross-linker was coated onto the surface of…[Read more]
-
Donaldson Wilkins posted an update 8 months ago
Although the text was seen as effective in the death HWLs, most participants dismissed the images. This research has implications for IT HWLs in Canada and globally. These results suggest that graphic images may be impactful in IT HWLs. Images must be supplemented with informative text that increases believability, relatability, and…[Read more]
-
Falk Balle posted an update 8 months ago
Mitral/tufted (MT) cells of the olfactory bulb (OB) show diverse temporal responses to odorant stimulation that are thought to encode odor information. Much of this diversity is thought to arise from inhibitory OB circuits, but the dynamics of excitatory input to MT cells, which is driven in a feedforward manner by sensory afferents, may also be…[Read more]
-
Richards Post posted an update 8 months ago
OBJECTIVE Episodic memory is impaired in Alzheimer’s disease (AD) dementia but thought to be relatively spared in behavioral variant frontotemporal dementia (bvFTD). This view is challenged by evidence of memory impairment in bvFTD. This study investigated differences in recognition memory performance between bvFTD and AD. METHOD We performed a…[Read more]
-
Ferrell Weeks posted an update 8 months ago
The mRNA level of MGMT was significantly associated with those of ESR1, GATA3 and FOXA1 in ER-positive breast tumor. Down-regulation of MGMT expression enhanced the proliferative and invasive capacities of breast cancer cells through PTEN/AKT pathway. Conclusions MGMT is a favorable biomarker with proliferation suppressive potential in ER-positive…[Read more]
-
Oconnor Lester posted an update 8 months ago
This article provides an overview of Charcot-Marie-Tooth disease (CMT) and other inherited neuropathies. These disorders encompass a broad spectrum with variable motor, sensory, autonomic, and other organ system involvement. Considerable overlap exists, both phenotypically and genetically, among these separate categories, all eventually exhibiting…[Read more]
-
McCormack Funch posted an update 8 months ago
AIMS To assess the performance of metabolic syndrome as a predictor of type 2 diabetes in a model that also includes both a measure of insulin resistance and a metabolic score for visceral fat, and to propose a novel metabolic syndrome definition. METHODS In a prospective metabolic syndrome cohort (n=6143), we evaluated improvements in type 2…[Read more]
-
Vognsen Sherrill posted an update 8 months ago
Multisystem proteinopathy (MSP) is a pleiotropic group of inherited disorders that cause neurodegeneration, myopathy, and bone disease, and share common pathophysiology. Originally referred to as inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD), attributed to mutations in the gene encoding…[Read more]
-
Ipsen Warming posted an update 8 months ago
This study is the first multi-center non-inferiority study that aims to critically evaluate the effectiveness of HHUS/ABUS in China breast cancer detection. This was a multicenter hospital-based study. Five hospitals participated in this study. Women (30-69 years old) with defined criteria were invited for breast examination by HHUS, ABUS or/and…[Read more]
-
Lamb Prince posted an update 8 months ago
SUMMARY The phenotype observed in Japan shows distinct clinical features compared with the classical phenotype, that is, increased levels of eosinophils, suggestive of ‘eosinophilic shift’ alongside symptomatic differences, making it difficult to categorize.BACKGROUND Previous studies have provided conflicting evidence about the increased overall…[Read more]
-
Husum Klit posted an update 8 months ago
Verbena officinalis (common vervain) is a medicinal plant species widely distributed in the world and commonly used in folk medicine of different countries, including traditional Chinese medicine. Monographs on “Verbenae herba” have been included in the European Pharmacopoeia since 2008, and in the Chinese Pharmacopoeia since 1995. This work…[Read more]
-
McHugh Eaton posted an update 8 months ago
We determined that mcm5-bob1 does not rescue the SDL and defects in proteolysis of GALCSE4 in a cdc7-7 strain, suggesting a DNA replication-independent role for Cdc7 in Cse4 proteolysis. The SDL phenotype, defects in ubiquitin-mediated proteolysis, and the mislocalization pattern of Cse4 in a cdc7-7 psh1Δ strain were similar to that of cdc7-7 and…[Read more]
-
Vasquez Stryhn posted an update 8 months ago
ister, ChiCTR1900028457. Copyright © 2020 Yang, Chen, Shao, Yan, Yue and Jiang.This study examines the effects of focused-attention meditation on functional brain states in novice meditators. There are a number of feature metrics for functional brain states, such as functional connectivity, graph theoretical metrics, and amplitude of low…[Read more]
-
George Tolstrup posted an update 8 months ago
Accordingly, the effect of miR-206 mimics was attenuated by the overexpression of KLF4 in adipocytes. Taken together, we identified the expression profiles of miRNAs in adipocytes, which revealed that miR-206 acts as a suppressor of adipogenesis.Gas chromatography-mass spectrometry (GC-MS) analysis revealed that castasterone and its biosynthetic…[Read more]
-
Bartlett Heide posted an update 8 months ago
The utilization of a wide spectrum of nonhost resistances can also be adopted once practical methods have been developed.
In gastroesophageal reflux disease (GERD), the additive effect of mosapride to a proton pump inhibitor (PPI) is still controversial. This meta-analysis integrated randomized controlled trials (RCTs) in which mosapride…[Read more]
-
Kara Parks posted an update 8 months ago
Comprehensive evaluations on datasets from the particle tracking challenge demonstrate the competitiveness of the proposed deep-learning method compared to the state of the art. Additional tests on real-time-lapse fluorescence microscopy images of various types of intracellular particles show the method performs comparably with human…[Read more]
-
Therkildsen Brantley posted an update 8 months ago
In summary, quantitative assessment of vascular permeability should be coupled with patency when studying the effect of perfusion decellularization on kidney vasculature. Flow-controlled angiography should be considered as method of choice for vascular assessment in bioengineered kidneys. Adopting this methodology for organs pre-modified ex-vivo…[Read more]
-
Karlsson Herndon posted an update 8 months ago
In the rapid desensitized group, except for neutropenia, there was no statistically significant increase in SAEs and over grade 3 of ADRs according to organ classes compared with the control group. In the efficacy analysis, TTP and OS were similar in the 2 groups.
Rapid desensitization of carboplatin can lower the risk of immediate…[Read more]
-
Wren Lindberg posted an update 8 months ago
4±2.5 mmol/L. 80.8% of patients were on lipid-lowering therapy with a mean treated LDL-cholesterol of 3.3±1.7 mmol/L. Among patients receiving lipid-lowering therapies, 25.6% achieved an LDL-cholesterol target of <2.5 mmol/L without CAD or <1.8 mmol/L with CAD.
Patients in the national FH registry are detected later in life, have a high b…[Read more]
-
Mack Rosa posted an update 8 months ago
This paper presents two studies on the development and validation of a ten-item scale of epistemic vice and the relationship between epistemic vice and misinformation and fake news. Epistemic vices have been defined as character traits that interfere with acquiring, maintaining, and transmitting knowledge. Examples of epistemic vice are…[Read more]
- Load More