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Bondesen Smedegaard posted an update 8 months ago
001). In both sides, significant differences in the timed 360° turn test times were found between PwPD and healthy people and between fallers and non-fallers with PD (p less then 0.001 and p less then 0.001, respectively). The timed 360° turn test times of 3.76-3.89 s were found to best discriminate PwPD from healthy people, while 5.46-5.74…[Read more]
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Reece Callahan posted an update 8 months ago
The problem of neurotoxicity associated with some anticancer drugs is also highlighted. Our review encourages further research to better encode the hidden potential of anticancer drugs with the aim of developing prospective repurposed drugs with no toxicity for neurodegenerative disorders.Spinal cord injury (SCI) is an independent risk factor for…[Read more]
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Knox Butler posted an update 8 months ago
gibility scores were also documented. We discuss these results within the context of cross-linguistic comparisons. What are the potential or actual clinical implications of this work? The results confirm the use of objective acoustic measures in the assessment of individuals with motor speech disorders, providing such data for Hebrew-speaking…[Read more]
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McHugh Eaton posted an update 8 months ago
We determined that mcm5-bob1 does not rescue the SDL and defects in proteolysis of GALCSE4 in a cdc7-7 strain, suggesting a DNA replication-independent role for Cdc7 in Cse4 proteolysis. The SDL phenotype, defects in ubiquitin-mediated proteolysis, and the mislocalization pattern of Cse4 in a cdc7-7 psh1Δ strain were similar to that of cdc7-7 and…[Read more]
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Holmgaard Cobb posted an update 8 months ago
chelonae in a patient without disseminated infection or pre-exposure to macrolides. The increasing prevalence of drug resistant NTM infections is an emerging concern for clinicians treating patients with complications related to medical tourism.
The re-emergence of tuberculosis (TB) worldwide, compounded by multi-drug resistance (MDR) of the…[Read more]
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Sunesen Tennant posted an update 8 months ago
ASD symptoms and developmental delays, emerging during the period when speech acquisition and prosody modulation development converge, could lead to compromised modulation abilities. Our research question focused on the presence of a prosodic signature that mirrors developmental levels and ASD symptom severity, evaluated in a cohort of 74 autistic…[Read more]
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Karlsson Herndon posted an update 8 months ago
In the rapid desensitized group, except for neutropenia, there was no statistically significant increase in SAEs and over grade 3 of ADRs according to organ classes compared with the control group. In the efficacy analysis, TTP and OS were similar in the 2 groups.
Rapid desensitization of carboplatin can lower the risk of immediate…[Read more]
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Konradsen Mooney posted an update 8 months ago
The role of the nervous system as a contributor in the tumor microenvironment has been recognized in different cancer types, including colorectal cancer (CRC). The gastrointestinal tract is a highly innervated organ system, which is not only innervated by the autonomic nervous system, but also contains an extensive nervous system of its own; the…[Read more]
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Richards Callahan posted an update 8 months ago
e US.DNA damage response (DDR) and repair pathways determine neoplastic cell transformation and therapeutic responses, as well as the aging process. Altered DDR functioning results in accumulation of unrepaired DNA damage, increased frequency of tumorigenic mutations, and premature aging. Recent evidence suggests that polypeptide hormones play a…[Read more]
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Hoffmann Mangum posted an update 8 months ago
In terms of OS, compared with placebo plus fulvestrant, abemaciclib plus fulvestrant, ribociclib plus fulvestrant, and buparlisib plus fulvestrant had a significant difference. The risks of ADEs were similar among three CDK4/6 inhibitors.
As second-line treatment, three CDK4/6 inhibitors showed superior clinical efficacy compared to other…[Read more]
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Rush Li posted an update 8 months ago
Programmes can be developed to create or improve healthy working environments to increase productivity.Athletic groin pain (AGP) is a chronic, painful condition which is prevalent in players of field sports that require rapid changes of direction. Following successful rehabilitation, systematic changes have been observed in the kinetics and…[Read more]
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Cummings Wolff posted an update 8 months ago
This growth represents the positive psychological changes that can occur after highly challenging life circumstances and, when successful, allows individuals to achieve a higher level of functioning by addressing and learning from the precipitating event. Our practices can support this growth through education, emotional regulation, and…[Read more]
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Gutierrez Guerrero posted an update 8 months ago
clinicaltrials.gov (NCT02709135).
clinicaltrials.gov (NCT02709135).Evaluations of replacement heifers in intensively managed grazing systems in tropical conditions are warranted. Thus, we aimed to evaluate performance, muscle and mammary gland development, oocyte quality, and in vitro production of embryos of crossbred heifers grazing an…[Read more]
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Perry Geisler posted an update 8 months ago
Microwave Radiometry (MWR) has the advantage that measurements of internal (i.e. deep) tissue temperature may be obtained non-invasively by measuring naturally emitted radiation in GHz range. Savolitinib The goal of the present study is to further the development of MWR for clinical application in assessment of patients with Low Back Pain (LBP).…[Read more]
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Huber Spears posted an update 8 months ago
Our data show that the solvent casting approach offers improved drug distribution within the polymeric matrix, as was observed from micro-computed topography and scanning electron microscopy visualization. Moreover, this approach shows a higher drug release rate and thus improved antibacterial efficacy. However, there were no differences among the…[Read more]
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Lindgren Karlsen posted an update 8 months ago
Formalin-fixed, paraffin-embedded (FFPE) specimens have huge potential as source material in the field of human microbiome research. However, the effects of FFPE processing on bacterial DNA remain uncharacterized. Any effects are relevant for microbiome studies, where DNA template is often minimal and sequences studied are not limited to one…[Read more]
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Due Hanley posted an update 8 months ago
The alternation of resorption of preexisting bone by the osteoclasts followed by de novo bone formation by osteoblasts is called bone modeling during childhood and bone remodeling during adulthood. A central question raised by this physiological process that is fundamental to longitudinal growth during childhood and adolescence and that is…[Read more]
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Mayo Bennetsen posted an update 8 months ago
In each pathway, individual experiences with vaping nicotine appeared to play an important role and appeared to be related to psychological and social factors. A social context supportive of vaping was important for the maintainers, as was a belief in the need to overcome nicotine addiction for the abstainers, and dislike of the ‘vaping culture’…[Read more]
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Sampson Voigt posted an update 8 months ago
e., body and chelae shapes) and trophic divergence (i.e., reliance on littoral carbon) among individuals from littoral and pelagic habitats, highlighting the existence of resource polymorphism in invasive populations. There was no genetic differentiation between individuals from the two habitats, implying that this resource polymorphism was stable…[Read more]
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Irwin Hanson posted an update 8 months ago
61, 95% confidence interval 0.47-0.80), and the methylation of Chr1776356190 or Chr1776356199 was negatively related to T2D in both men and women. Moreover, testosterone was positively associated with Chr1776356190 methylation in men and Chr1776356199 methylation in women (both P < .05). The mediation analysis showed that the Chr1776356190 met…[Read more]
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