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Sweet Hatfield posted an update 1 year ago
ity of oral anticancer agents cause QT prolongation with direct and indirect mechanisms, potentially resulting in the occurrence of torsade de pointes, especially in susceptible patients with COVID-19 receiving additional drugs with QT liability. Oncologists and cardiologists must be aware of the increased bleeding risk and arrhythmic…[Read more]
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Wentworth Risager posted an update 1 year ago
The determined crystal structure of the Syntaxin17 LIR-GABARAP complex not only provides mechanistic insights into the interaction between Syntaxin17 and GABARAP but also reveals an unconventional LIR motif with a C-terminally extended 310 helix for selectively binding to ATG8 family proteins. Finally, we also elucidated structural arrangements of…[Read more]
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MacGregor Milne posted an update 1 year ago
Results With ART criteria, success rates of ART and composite restoration were found to be 98.7% and 100% at 6 months while at 12 months the success rates were observed to be 98.7% and 95.8%, respectively. The distribution of scores at both the time periods was found to be statistically significant (p = 0.033). Same success rates were observed…[Read more]
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Covington Oneil posted an update 1 year ago
In Chile, necrotizing enterocolitis (NEC) mainly affects preterm infants, with an incidence of 0.3 to 2.4 per 1,000 live births, and 8 to 12% in preterm infants weighing less than 1,500 grams.
To describe health professionals perceptions on the use of human colostrum as a preventive measu re against necrotizing enterocolitis in preterm…[Read more]
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Xu Kejser posted an update 1 year ago
05), but the difference in SBS between the adhesive group and the primer group was not significant (P>0.05). After thermalcycling, the SBS of the three types of resin cements decreased (P<0.05); the SBS of the adhesive group was higher than that of the direct adhesive group and the primer group (P<0.05). Fracture mode analysis revealed that the…[Read more]
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Hvid Lamb posted an update 1 year ago
es and Delivery Research programme. BACKGROUND Severe mental illness diagnoses have overlapping symptomatology and shared genetic risk, motivating cross-diagnostic investigations of disease-relevant quantitative measures. We analysed relationships between neurocognitive performance, symptom domains, and diagnoses in a large sample of people with…[Read more]
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Goldberg Kemp posted an update 1 year ago
Purpose Rates of obesity and obesity-related health consequences, including type 2 diabetes (T2D) and cancer, continue to rise. While cancer patients are at an increased risk of developing T2D, the prevalence of T2D and insulin prescription among young patients with cancer remains unknown. Methods Using the Total Cancer Care Study cohort at…[Read more]
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Mattingly Asmussen posted an update 1 year ago
Pulse laser treatment is useful for aesthetic improvement in children with capillary vascular malformation and residual superficial haemangiomas. However, pulse laser treatment is painful, and repeated procedures are usually required to achieve a satisfactory clinical result. Evidence shows that analgesia in children undergoing pulse laser…[Read more]
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Madden Stage posted an update 1 year ago
Detecting microsatellite instability (MSI) in colorectal cancer is crucial for clinical decision making, as it identifies patients with differential treatment response and prognosis. Universal MSI testing is recommended, but many patients remain untested. A critical need exists for broadly accessible, cost-efficient tools to aid patient selection…[Read more]
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Espinoza Vinding posted an update 1 year ago
These hanging cell culture inserts are thus a potent product for various cell culture assays such as cell migration for wound healing, cancer metastasis, and other tissue engineering applications.We investigated the magnetic control of the Mn photoluminescence (PL) in iron oxide/l-cysteine-capped zinc sulfide (Fe3O4/l-cys ZnSMn) nanocomposites via…[Read more]
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Vick Lee posted an update 1 year ago
Cowpea (Vigna unguiculata (L.) Walp) is an important multipurpose legume crop grown in arid and semi-arid areas of sub-Saharan Africa. The crop associates with a wide diversity of high ecological value rhizobia bacteria, improving biological soil fertility and crop production. Here, we evaluated the symbiotic efficiency (SE) and genetic diversity…[Read more]
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Mead Brandt posted an update 1 year ago
There is increasing clinical evidence of an association between gender variability, gender dysphoria (GD), and autism spectrum disorder (ASD). This seems to be a two-way relationship, a person with GD is more likely to be diagnosed with ASD and vice versa. In youth, it is important to distinguish whether the presented symptoms are a manifestation…[Read more]
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Skaarup Shelton posted an update 1 year ago
1% to 6.1%], using 450-ml glasses was 1.0% higher (95% CI = -9.1 to 12.2) and using 510-ml glasses was 0.4% lower (95% CI = -9.4 to 9.4). For restaurants, compared with 300-ml glasses, the volume of wine sold using 250-ml glasses did not show a significant difference 9.6% lower (95% CI = -19.0 to 0.7). Using 370-ml glasses the volume of wine sold…[Read more]
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Karlsen Bowen posted an update 1 year ago
Although there are some methodological limitations, the findings imply that the relationship between FTP, TLL, and emotion regulation that is assumed in the SST should be reconsidered and that TLL should be thought of as a distinct variable from FTP. © Springer Nature B.V. 2019.Social exclusion is complex and dynamic, and it leads to the…[Read more]
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Aagesen Schack posted an update 1 year ago
Most prostate cancer (PCa) deaths result from progressive failure in standard androgen deprivation therapy (ADT), leading to metastatic castration-resistant PCa (mCRPC); however, the mechanism and key players leading to this are not fully understood. While studying the role of tousled-like kinase 1 (TLK1) and never in mitosis gene A (NIMA)-related…[Read more]
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Allen Rooney posted an update 1 year ago
Several fungal strains promoted leaf or root growth. In particular, a strain belonging to the genus Diaporthe caused an increase in leaf and root biomass in both screening processes, suggesting that this endophyte might have a good potential for field application in tritordeum.High nitrogen application aimed at increasing crop yield is offset by…[Read more]
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Rees McElroy posted an update 1 year ago
This study contributes to clarifying the pheromone perception in the FAW, and provides potential gene targets for developing OR-based pest control techniques.In this paper, the syntheses of a set of cerium-bismuth mixed oxides with the formula Ce1-xBixO2-x/2, where the range of x is 0.0 to 1.0 in 10 mol% steps, via co-precipitation methods is…[Read more]
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Skovbjerg Boisen posted an update 1 year ago
To explore the role of prostacyclin (PGI2) and thromboxane A2 (TXA2) in lung hyper-permeability induced by mechanical ventilation (MV) in rabbits.
Forty-eight healthy Japanese white rabbits were randomly allocated to vehicle treatment group (group V), tranylcypromine (a PGI2 synthase inhibitor) treatment group (group T), dazoxiben (a TXA2…[Read more]
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Bennetsen Espinoza posted an update 1 year ago
We also include a discussion on the mechanistic action of NMP, comparison of subnormothermic and hypothermic conditions, the different logistical approaches and future requirements.
Germline and somatic mutations of DICER1 have been identified in various types of neoplastic lesions, with germline DICER1 mutation being linked to autosomal…[Read more]
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Kofod Gray posted an update 1 year ago
In the early 1990s, several studies reported the misuse of codeine and promethazine hydrochloride cough syrup. Since then, the combination of this pharmaceutical, together with sprite or alcohol, known on the streets as “purple drank” or “lean”, has become a popular drug among rap singers who promote its tranquilizing and euphoric effects through…[Read more]
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