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Beach George posted an update 9 months, 2 weeks ago
Importance Nonalcoholic steatohepatitis (NASH) is the inflammatory subtype of nonalcoholic fatty liver disease (NAFLD) and is associated with disease progression, development of cirrhosis, and need for liver transplant. Despite its importance, NASH is underrecognized in clinical practice. Observations NASH affects an estimated 3% to 6% of the US…[Read more]
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Norman Diaz posted an update 9 months, 2 weeks ago
6 Pa along the free margin, with WSS progressively decreasing towards the belly. During diastole, the aortic side of the fused leaflet exhibited the highest diastolic maximum principal stress, up to 322 kPa within the attachment region. Systematic comparison with ground-truth non-invasive MRI can improve the computational model ability to…[Read more]
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Penn Moser posted an update 9 months, 2 weeks ago
The rolled Al-2Fe-0.3Co alloy exhibits the highest thermal conductivity, which is about 225 W/(m·K), approximately 11 % higher than the as-cast Al-2Fe sample. The ultimate tensile strength (UTS) and elongation (EL) of as-cast Al-2Fe-0.5Co (UTS 138 MPa; EL 22.0 %) are increased by 35 % and 69 %, respectively, compared with those of unmodified…[Read more]
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Steele McGinnis posted an update 9 months, 2 weeks ago
This paper studies the convective heat transfer of a hybrid nanofluid in the inclined channel, whose walls are both heated by the uniform heat flux. The governing ordinary differential equations are made nondimensional and solved analytically, in which explicit distributions of velocity, temperature and pressure are obtained. The effects of flow…[Read more]
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Rode Crowder posted an update 9 months, 2 weeks ago
Objective To investigate the computed tomography(CT)imaging features of IgG4-related kidney disease(IgG4-RKD).Methods The clinicopathological and imaging data of 36 IgG4-RKD patients(including 26 cases of renal parenchyma,10 cases of renal pelvis,24 cases of double kidney or multiple lesions,and 12 cases of single focus)were retrospectively…[Read more]
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Stevens Mcclain posted an update 9 months, 2 weeks ago
3, 95% CI 1.26-67.74) and meconium stained amniotic fluid (aOR 2.1, 95% CI 1.10-3.85). Parturients who underwent re-suturing had significantly higher rates of postpartum hemorrhage (78.5% vs. 11.4%) blood transfusions (36.2% vs. 1.3%), puerperal fever, and longer hospitalizations (P less then 0.01 for all). Conclusion In our population, early…[Read more]
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Wooten Murdock posted an update 9 months, 2 weeks ago
This review is tailored to outline the known effects of the current anti-diabetic drugs, anti-inflammatory therapies, and natural compounds on inflammation, which mitigate HF progression in diabetic populations.Metabolic syndrome is associated with hypercholesterolemia, cardiac remodeling, and increased susceptibility to ventricular arrhythmias.…[Read more]
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Palmer Reeves posted an update 9 months, 2 weeks ago
Alzheimer’s disease (AD) is the most common age-related progressive neurodegenerative disease, characterized by a decline in cognitive function and neuronal loss, and is caused by several factors. Numerous clinical and experimental studies have suggested the involvement of gut microbiota dysbiosis in patients with AD. The altered gut microbiota…[Read more]
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Yde Malloy posted an update 9 months, 2 weeks ago
This article reviews four emerging endovascular hemorrhage control and extracorporeal perfusion techniques for management of trauma patients with profound hemorrhagic shock including hemorrhage-induced traumatic cardiac arrest. These include resuscitative endovascular balloon occlusion of the aorta (REBOA), selective aortic arch perfusion (SAAP),…[Read more]
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Gould Rafn posted an update 9 months, 2 weeks ago
This proof-of-concept-study demonstrated the usability and reproducibility of Nephroscreen for the detection of DIKI and drug-transporter interactions. Nephroscreen it represents a valuable tool towards replacing animal testing and supporting the 3Rs (Reduce, Refine and Replace animal experimentation).
Polysorbates (PS) are used in…[Read more]
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Randall Hougaard posted an update 9 months, 2 weeks ago
argeting miR-211-5p and the downstream gene ACSL4 will possibly provide novel insight and represents a promising approach to future therapy of HCC patients.
Targeting miR-211-5p and the downstream gene ACSL4 will possibly provide novel insight and represents a promising approach to future therapy of HCC patients.
Revision ankle-fusion…[Read more]
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Mays Upchurch posted an update 9 months, 2 weeks ago
0001).In patients with early ISR lesions, the LDL-C levels may be related to the formation and progression of early neoatherosclerosis, and poor LDL-C control may be a risk factor for the occurrence of early-stage neoatherosclerosis following DES implantation.Previous study has identified marked differences in patient characteristics and causes of…[Read more]
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Bonner Clifford posted an update 9 months, 2 weeks ago
In some countries, including China, primary health care is rarely utilized because of medical personnel shortages at primary medical and health care institutions (PMHCIs). Several studies suggest that the most effective solution is to guide qualified doctors and medical graduates to work in PMHCIs, but the studies and measures have been formulated…[Read more]
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Hassan Staal posted an update 9 months, 2 weeks ago
Currently, clinical treatment for temozolomide (TMZ)-resistant glioblastoma multiforme (GBM) is still a difficult problem. The aim of this paper is to set up a new GBM-targeted drug delivery system to treat TMZ-resistant GBM. Zoledronate (ZOL) not only induces apoptosis of TMZ-resistant GBM cells by down-regulation of farnesyl pyrophosphate…[Read more]
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Zachariassen Wollesen posted an update 9 months, 2 weeks ago
This study was planned to continue our previous study to assess effect of combination therapy bone marrow stromal cells (BMSCs) with exercise (EX) and triiodothyronine (T3) on stroke-induced astrogliosis in mice. Stroke subjected-mice were divided into five monotherapy groups including sham, control, BMSCs, EX and T3; and three combination therapy…[Read more]
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Womble Healy posted an update 9 months, 2 weeks ago
These findings provide novel evidence that RGCs exhibit reduced light-dependent adaptation and increased excitability when IOP is elevated to low but not high levels. These results may reveal functional changes that occur early in glaucoma, which can potentially be used to identify patients with glaucoma at earlier stages when intervention is most…[Read more]
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Hayes Burnett posted an update 9 months, 2 weeks ago
omplex examination of UC patients. Further clinical studies are necessary for assessment of the efficiency of anti-Blastocystis therapy in UC patients.
Diagnosis of Blastocystis sp. should be introduced in the complex examination of UC patients. Further clinical studies are necessary for assessment of the efficiency of anti-Blastocystis therapy…[Read more]
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Lykke Degn posted an update 9 months, 2 weeks ago
45% (5 in 11 isolates), while combinations of colistin with imipenem or ceftolozane and tazobactam displayed 36.36% (4 of 11 isolates) and 63.64% (7 of 11 isolates) synergism. In addition, combinations of colistin with levofloxacin was synergistic against 90.91% (10 of 11 isolates). The results revealed that combinations of colistin with other…[Read more]
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Josephsen Estes posted an update 9 months, 2 weeks ago
Platelet-rich plasma (PRP) has potential uses for patients with spinal cord injuries (SCI). However, no study has quantified the cellular and growth factor (GF) content of PRP in this population. This study aimed to analyze 1) PRP content of SCI subjects and 2) the effect of high intensity interval exercise (HIIE) on their PRP.
10 SCI…[Read more]
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Emerson Slaughter posted an update 9 months, 2 weeks ago
Evidence to support this includes the significant differences between samples using PERMANOVA (p less then 0.001), the clear separation in ordination space of samples clustered by sampling method, the significantly higher richness in the surface samples (p less then 0.001), and the considerable variation in relative abundances of various taxa and…[Read more]
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