• The continuing advancements in technology have resulted in an explosion in the use of interconnected devices and sensors. Internet-of-Things (IoT) systems are used to provide remote solutions in different domains, like healthcare and security. A common service offered by IoT systems is the estimation of a person’s position in indoor spaces, which…[Read more]

  • 01). The absolute values of forced vital capacity (FVC) forced expiratory volume in the first second (FEV

    ), peak expiratory flow (PEF), forced expiratory flow during mid-expiration (FEF

    ), and FEV

    /FVC ratio showed no significant differences between groups. However, the percentage of the predicted values of FEV

    and FVC was…[Read more]

  • Recent advances in metabolomics provide tools to investigate human metabolome in order to establish new parameters to study different approaches towards diagnostics, diseases and their treatment. The present study focused on the untargeted identification of metabolites in serum of patients with coronary artery disease who were under treatment at…[Read more]

  • .

    Accurate prediction of cancer types can be achieved with existing electronic health record data with satisfactory precision. The integration of genetic reports improves prediction, illustrating the translational values of incorporating genetic tests early at the diagnosis stage for patients with cancer.

    Digital imaging of dermatological…[Read more]

  • Many mitochondrial diseases are caused by mutations in mitochondrial DNA (mtDNA). Patients’ cells contain a mixture of mutant and nonmutant mtDNA (a phenomenon called heteroplasmy). The proportion of mutant mtDNA varies across patients and among tissues within a patient. We simultaneously assayed single-cell heteroplasmy and cell state in…[Read more]

  • n the asthma trial were lower than in atopic dermatitis trials and were similar for dupilumab- and placebo-treated patients. Most events were mild to moderate, most recovered/resolved, and none prompted study withdrawal. These results are similar to those reported in adult trials and support a drug-disease interaction. CLINICALTRIALS.…[Read more]

  • Downregulated genes (N = 363) were enriched in annotations associated with behavior (FDR less then 2 × 10-4 ), membrane organization (FDR less then 1 × 10-4 ), inorganic cation transmembrane transporter activity (FDR less then 2 × 10-3 ), synapse part (FDR less then 4 × 10-10 ), glutamatergic synapse (FDR less then 1 × 10-6 ), and GABAergic syna…[Read more]

  • In this cohort, the average age was 56.5 years, 63.9% were female, and 36.5% of patients developed the primary outcome. The incidence of the primary outcome was higher in those initially treated with either norepinephrine (47.6%) or dopamine (50.6%) than with phenylephrine (24.5%). After adjusting for possible confounders using propensity score…[Read more]

  • Seven patients reported positive SARS-CoV-2 exposure from a member of their household.

    Hospitalized patients on PD with COVID-19 had a relatively mild course, and majority of them were discharged home.

    Hospitalized patients on PD with COVID-19 had a relatively mild course, and majority of them were discharged home.

    Accurate…[Read more]

  • These data expand the catalogue of functional elements encoded in the human genome by the addition of a large set of elements that function at the RNA level by interacting with RBPs.During mammalian embryogenesis, differential gene expression gradually builds the identity and complexity of each tissue and organ system1. Here we systematically…[Read more]

  • To date, treatment of atrophic acne scars remains a therapeutic challenge for dermatologists, yet there is no standard option on the most effective treatment. Microneedling (MN) is a minimally invasive technology that involves repetitive skin puncture using sterile microneedles to disrupt dermal collagen that connects the scar tissue. Recent…[Read more]

  • Poly(N-vinylpyrrolidone-co-butylacrylate-co-N-hydroxymethylacrylamide) has been synthesized by free radical polymerization at 70 °C. Copolymer were characterized by FT-IR, elemental analysis and viscometric methods. Invertase was immobilized onto poly(N-vinyl pyrrolidone-co-butyl acrylate-co-N-hydroxymethyl acrylamide) by entrapment method.…[Read more]

  • mpatibility with HUVECs, but had no effect on L-929 cell viability. Principle Conclusions We report the development and characterization of a new, dual-functional embolization-visualization system for improving fluorescence-imaged endoscopic surgical resection of hypervascular tumors. © The author(s).Rationale Epigenetic mechanisms are…[Read more]

  • We find that the more complicated dependence of DOP on strain, as derived by the analytic model, fits the data better than the previously assumed simple dependence. This finding thus corroborates the analytical model and should have an impact on understanding the strain-dependent operation of optoelectronic devices.

    To explore whether…[Read more]

  • We suggest that this could be because only higher scores in the GII between men and women show health benefits.

    The cost-sharing impact on hospital service utilization of different services is a critical issue that has not been well addressed worldwide. This study aimed to investigate the cost-sharing effects based on income status on hospital…[Read more]

  • Ocular hypertension occurs due to increased resistance to aqueous humor removal through the conventional outflow pathway. Unlike the proximal region of the conventional outflow pathway, the distal region has not been well studied, mostly due to lack of model systems. Here we describe isolation and characterization of human primary vascular distal…[Read more]

  • Results reveal that nursing diagnoses related to universal self-care requisites can emphasize the impairment or potentialities of the individuals performing self-care. It also shows a lack of consensus on nominating the nursing diagnoses of people with a deficit in universal self-care requisites, resulting in different diagnoses to express the…[Read more]

  • Depressive symptoms in early adulthood were indirectly related to major depressive disorder (MDD) through two independent paths, including the stability of depressive symptoms over time, and through the influence of depression on increasing the tendency to use substances to cope with stress. Our results underscore that coping effects provide…[Read more]

  • The formation of the epiphyseal bone plate, the flat bony structure that provides strength and firmness to the growth plate cartilage, was studied in the present study by using light, confocal, and scanning electron microscopy. Results obtained evidenced that this bone tissue is generated by the replacement of the lower portion of the epiphyseal…[Read more]

  • Humans have unique cognitive capacities that, compared with apes, are not only simply expressed as a higher level of general intelligence, but also as a quantitative difference in sociocognitive skills. Humans’ closest living relatives, bonobos (Pan paniscus), and chimpanzees (Pan troglodytes), show key between-species differences in social…[Read more]

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