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Lee Kenney posted an update 9 months, 3 weeks ago
Additionally, the PLQY and FWHM of IPQD/CNC are 45.69% and 22 nm, respectively. The ultrahigh stability and narrow FWHM characteristics proposed here for IPQD/CNC hybrid films can provide new possibilities for practical applications in the future development of IPQD-related devices.Pulmonary fibrosis (PF) is a lethal fibrotic lung disease. The…[Read more]
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Berthelsen Chu posted an update 9 months, 3 weeks ago
Both Oncotype-trained and Prosigna-trained results further stratified MammaPrint-trained low risk cases, and MammaPrint-trained results also stratified Oncotype-trained low and intermediate risk groups but not Prosigna-trained results. Comparisons between existing multiparametric tests are challenging, and evidence on discordance between tests in…[Read more]
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Konradsen Beard posted an update 9 months, 3 weeks ago
Synchronous colorectal cancer liver metastasis (CRLM) has been viewed as being more aggressive and having shorter survival than metachronous disease. Advances in CRLM management led us to examine differences in treatment characteristics of synchronous versus metachronous CRLM patients along with survival and recurrence.
A retrospective…[Read more]
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Guzman Espensen posted an update 9 months, 3 weeks ago
Asymmetric warming resulting in a faster increase in night compared to day temperatures affects crop yields negatively. Physiological characterization and agronomic findings have been complemented more recently by molecular biology approaches including transcriptomic, proteomic, metabolomic and lipidomic investigations in crops exposed to high…[Read more]
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Lauridsen Covington posted an update 9 months, 3 weeks ago
. Rheumatologists should be aware of these comorbidities, especially in the era of COVID-19 pandemic.Irritable bowel syndrome (IBS) is the commonest cause of recurrent abdominal pain in children in both more developed and developing parts of the world. It is characterized by abdominal pain that is improved by defecation and whose onset is…[Read more]
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Elgaard Baird posted an update 9 months, 3 weeks ago
CBPA-GFP was quickly expressed in the Gm gut lumen, and more Bt HD73 strain bacteria adhered to the PM than those of the ∆cbpA mutant strain. Therefore, CBPA may help to retain the bacteria, via the PM binding, close to the gut surface and thus takes part in the early steps of Bt gut interactions.Continuously evolving laser devices can be used i…[Read more]
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Vittrup Rogers posted an update 9 months, 3 weeks ago
Aromatase inhibitors (AIs) are indicated in the treatment of hormone-receptive breast cancer in postmenopausal women in various settings. Studies have shown that they are effective when used as adjuvant therapy to chemotherapy and surgery in metastatic estrogen-dependent breast cancer. Their use in preventative and adjuvant therapies for other…[Read more]
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Templeton Lehmann posted an update 9 months, 3 weeks ago
This review will discuss the mechanisms of Ca2+ dysregulation in AD and associated pathology and discuss potential approaches or strategies to develop novel drugs for the treatment of AD by targeting Ca2+ dysregulation.Background Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and long noncoding RNAs (lncRNAs),…[Read more]
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Lopez Marshall posted an update 9 months, 3 weeks ago
Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) are two human neglected tropical diseases that cause major disabilities. Mass administration of drugs targeting the microfilarial stage has reduced transmission and eliminated these diseases in several countries but a macrofilaricidal drug that kills or sterilizes the adult…[Read more]
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Nyborg Spence posted an update 9 months, 3 weeks ago
Glioblastoma multiforme (GBM) is the most common and deadliest form of brain tumor and remains amongst the most difficult cancers to treat. Brevican (Bcan), a central nervous system (CNS)-specific extracellular matrix protein, is upregulated in high-grade glioma cells, including GBM. A Bcan isoform lacking most glycosylation, dg-Bcan, is found…[Read more]
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Lacroix Hahn posted an update 9 months, 3 weeks ago
Epigenetic regulators have been implicated in tumorigenesis of many types of cancer; however, their roles in endothelial cell cancers such as canine hemangiosarcoma (HSA) have not been studied. In this study, we find that lysine-specific demethylase 2b (KDM2B) is highly expressed in HSA cell lines compared with normal canine endothelial cells.…[Read more]
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Spencer Bonner posted an update 9 months, 3 weeks ago
We detected associations between bacterial abundance and metabolite levels, using a compositionality-aware approach-Rothia and Staphylococcus levels were positively associated with creatinine and urea levels, respectively. Our findings indicate that the gut microbial community contains specific members whose presence might ameliorate or, on the…[Read more]
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Terp Yildiz posted an update 9 months, 3 weeks ago
To evaluate the early prognosis and management of acute coronary involvement (ACI) in type A aortic dissection (ATAAD) patients without myocardial ischemia (MI).
We conducted a retrospective cohort study on a multicenter database. A total of 931 ATAAD patients without MI underwent thoracic aortic surgery between 2018 and 2019 in the Acute…[Read more]
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Sexton Adcock posted an update 9 months, 3 weeks ago
In this review, we highlight the design and construction of conceptually interesting and clinically viable actively targeted cancer nanomedicines containing small molecular drugs, nucleic acid drugs, or protein/peptide drugs, discuss their pros and cons, and give perspectives on the future developments and clinical translation. We are convinced…[Read more]
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Hassing Grantham posted an update 9 months, 3 weeks ago
The pandemic witnessed a significant increase in insomnia, burnout, and functional limitations among healthcare professionals, as shown by this study. A marked escalation in healthcare professional job burnout and functional impairment was observed during the pandemic. Moreover, specific groups at elevated risk are singled out, suggesting a need…[Read more]
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Birch McKenna posted an update 9 months, 3 weeks ago
Liver glycogen, a highly branched glucose polymer, is important for blood sugar homeostasis. It comprises α particles which are made of linked β particles; the molecular structure changes diurnally. In diabetic liver, the α particles are fragile, easily breaking apart into β particles in chaotropic agents such as dimethyl sulfoxide. We here use…[Read more]
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Strong Pereira posted an update 9 months, 3 weeks ago
Puberty is a complex process that culminates in the acquisition of psychophysical maturity and reproductive capacity. This elaborate and fascinating process marks the end of childhood. Behind it lies a complex, genetically mediated neuroendocrine mechanism through which the gonads are activated thanks to the fine balance between central inhibitory…[Read more]
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Edvardsen Terkildsen posted an update 9 months, 3 weeks ago
This favors the adsorption of the *OH, and stabilized *O radicals are reached, toward competitively lower overpotential, demonstrating a generalized key for optimally boosting overall OER performance.Endobronchial-invasive lung cancers are generally diagnosed at advanced stages and may require emergency treatment for airway obstruction. Stent…[Read more]
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Byrd Templeton posted an update 9 months, 3 weeks ago
plasia, deepening trochleoplasty and concomitant realignment procedures significantly reduced pain and improved knee joint function while normalizing patellotrochlear congruence.Childhood lung infection is often associated with prominent neutrophilic airway inflammation and excess production of proteases such as neutrophil elastase (NE). The…[Read more]
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Lorentsen Armstrong posted an update 9 months, 3 weeks ago
Cytochromes P450 (P450s) are a large superfamily of heme-containing monooxygenases. P450s are found in all Kingdoms of life and exhibit incredible diversity, both at sequence level and also on a biochemical basis. In the majority of cases, P450s can be assigned into one of ten classes based on their associated redox partners, domain architecture…[Read more]
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