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McGarry Adams posted an update 1 year ago
A new locking screw technology, named variable fixation, has been developed aiming at promoting bone callus formation providing initial rigid fixation followed by progressive fracture gap dynamisation. In this study, we compared bone callus formation in osteotomies stabilized with standard locking fixation against that of osteotomies stabilized…[Read more]
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Stryhn Upton posted an update 1 year ago
The cerebellum plays a crucial role in sensorimotor and associative learning. However, the contribution of molecular layer interneurons (MLIs) to these processes is not well understood. We used two-photon microscopy to study the role of ensembles of cerebellar MLIs in a go-no go task where mice obtain a sugar water reward if they lick a spout in…[Read more]
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Diaz Templeton posted an update 1 year ago
Our case report demonstrated the relevance of DDGI in clinical practice management of a patient treated for advanced breast cancer, suggesting the role of Drug-PIN software as an easy-to-use tool to prevent adverse events during cancer treatment and to help physicians in therapeutic algorithms. However, further studies are needed to confirm these…[Read more]
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Pritchard Humphries posted an update 1 year ago
The average plasma volume treated was 22 L. Efficacy of the IA column in log titer reduction of anti-ABO titer was 4 logs after the first use, 3 logs after 1
reuse, and 1.5 logs after 2
reuse. 12 (75%) patients successfully reached the target IgG titer of ≤14 solely with column reuse. One patient received a single session of plasma e…[Read more]
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Sehested Hjorth posted an update 1 year ago
Alzheimer’s disease (AD) is the most common form of dementia that progressively disrupts neurocognitive function, which has neither cure nor effective treatment. Hypercholesterolemia might be involved in brain alterations that could evolve into AD. The present study aims to evaluate the potential of omega-3, Co-enzyme Q10 (Co-Q10), as well as…[Read more]
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Cox Berthelsen posted an update 1 year ago
Depressive symptoms in early adulthood were indirectly related to major depressive disorder (MDD) through two independent paths, including the stability of depressive symptoms over time, and through the influence of depression on increasing the tendency to use substances to cope with stress. Our results underscore that coping effects provide…[Read more]
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Arsenault Figueroa posted an update 1 year ago
The resolution of the Tree of Life has accelerated with advances in DNA sequencing technology. To achieve dense taxon sampling, it is often necessary to obtain DNA from historical museum specimens to supplement modern genetic samples. However, DNA from historical material is generally degraded, which presents various challenges. In this study, we…[Read more]
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Bertelsen Frazier posted an update 1 year ago
Comparisons between groups using unsupervised clustering identified differences in proportions of clusters within T-cells, B-cells and myeloid cells. Manual gating confirmed increased memory T-regulatory and central memory CD4+ T-cells, with altered expression of T-cell, B-cell, and dendritic cell markers. Conclusions This study demonstrates a…[Read more]
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Waugh McDonough posted an update 1 year ago
rative infection.Introduction Urothelial cancers (UC) include tumors of the bladder, upper tract, and proximal urethra. Bladder cancer (BC) arises from urothelial cells lining the bladder and accounts for 90-95% of UC. BC is responsible for approximately 500,000 new cases and has a dismal prognosis with 200,000 deaths annually globally. However,…[Read more]
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Burton Cameron posted an update 1 year ago
To using finite element analysis to investigate the effects of the traditional titanium alloy Gamma nail and a biodegradable magnesium alloy bionic Gamma nail for treating intertrochanteric fractures.
Computed tomography images of an adult male volunteer of appropriate age and in good physical condition were used to establish a…[Read more]
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Wind Bredahl posted an update 1 year ago
Micro decisions, made by individuals, during a health crisis in which healthcare resources are particularly in short supply, should not be based only on the age of the patients. Ameliorate care is only appreciated when the patient has a limited time to live, whatever their age. Macro decisions concern public policy. We must decide now who will pay…[Read more]
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Reyes Somerville posted an update 1 year ago
The successful determination and analysis of phenotypes plays a key role in the diagnostic process, the evaluation of risk factors and the recruitment of participants for clinical and epidemiological studies. The development of computable phenotype algorithms to solve these tasks is a challenging problem, caused by various reasons. Firstly, the…[Read more]
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Bryan Brewer posted an update 1 year ago
aureus load in the tissues. The overexpression levels of IL-1β, TNF-α, and IL-6 induced by S. aureus were inhibited after OS treatment. Furthermore, the increased phosphorylation of NF-κB and MAPKs proteins were also suppressed. The results suggest that dietary supplementation with adequate OS during pregnancy contributes to protect the mammary gl…[Read more]
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Tillman Doherty posted an update 1 year ago
The overall and cause-specific survival was 96% and 86% at 3 and 5 years. No late complications related to brachytherapy were described. Conclusion A HDR-BT boost is useful to decrease the incidence of local recurrence of NPC to 5%. With a fractionated schedule of 3-4 fractions in two days, Rotterdam applicator and 3-D planning, no late…[Read more]
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Browne Hede posted an update 1 year ago
The aim of the present study was to compare the outcomes of pregnancies complicated by preterm premature rupture of membranes (PPROM) in China.
The present study was a single-center retrospective study of women admitted to Beijing Obstetrics and Gynecology Hospital in 2012, 2014, and 2017. Deliveries at <24 and >37 weeks, fatal…[Read more]
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Breen Templeton posted an update 1 year ago
Maca (Lepidium meyenii) has emerged as a popular functional plant food because of its medicinal properties and nutritional value. Macamides, as the exclusively active ingredients found in maca, are a unique series of non-polar, long-chain fatty acid N-benzylamides with multiple bioactivities such as antifatigue characteristics and improving…[Read more]
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Wells Whitney posted an update 1 year ago
This study aimed to compare the efficacy and safety of ultrasound-guided percutaneous microwave ablation (MWA) for hepatocellular carcinoma (HCC) adjacent to large vessels with those far from large vessels.
The clinical data of patients who underwent ultrasound-guided percutaneous MWA for HCC were retrospectively analyzed between January…[Read more]
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Franks Hald posted an update 1 year ago
on the molecular changes in exstrophy-epispadias complex bladders and may have implications on the appropriate timing of primary bladder closure, as those closed in the newborn period appear to have a greater potential for growth and differentiation.
The urothelium in the exstrophy-epispadias complex bladder is strikingly different than that of…[Read more]
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Mccullough Horton posted an update 1 year ago
Time-processing disorders in adults is a priority area for intervention. Time management program, which has been demonstrated to be effective in children with ADHD, has not been examined in adults. We anticipate the need for the development of specialized programs for adults. This is because it has been reported that time processing disorders have…[Read more]
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Lindgren Penn posted an update 1 year ago
Lung squamous cell carcinoma (LSCC) is the second most prevalent type of lung cancer. Despite extensive genomic characterization, no targeted therapies are approved for the treatment of LSCC. Distal amplification of the 3q chromosome is the most frequent genomic alteration in LSCC, and there is an urgent need to identify efficacious druggable…[Read more]
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