• Wilson McGinnis posted an update 8 months ago

    CONCLUSION The 46TT genetype, p.Glu502Lys and p.Gly542Ser variants of the F12 gene probably underlie the low FXII level in the proband. As shown by in vitro experiment, the p.Glu502Lys and p.Gly542Ser variants can both inhibit the synthesis and secrection of the FXII protein.OBJECTIVE To analyze the clinical phenotype of six pedigrees affected…[Read more]

  • Buckley Bennetsen posted an update 8 months ago

    To externally validate a Genomic Classifier (GC) based risk-stratification nomogram identifying candidates who would benefit from adjuvant radiation (aRT) therapy after radical prostatectomy (RP).

    We identified 350 patients who underwent RP, between 2013 and 2018, and had adverse pathological features (positive margin, and/or pT3a or…[Read more]

  • Gupta Lykke posted an update 8 months ago

    Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. To revert type 1 diabetes, the suppression of the autoimmune attack should be combined with a β-cell replacement strategy. It has been previously demonstrated that liraglutide, a glucagon-like peptide-1 receptor agonist, restores β-cell mass in ty…[Read more]

  • McFarland Ryberg posted an update 8 months ago

    The emergence of various controlling strategies renders the composting products safer. Four potential removal mechanisms of ARGs in different controlling strategies have been concluded, encompassing the attenuation of selective/co-selective pressure on ARGs, killing the potential host bacteria of ARGs, reshaping the structure of bacterial…[Read more]

  • Barrera Collins posted an update 8 months ago

    Xanthates are widely used in mining industry as collectors for its high affinity towards metal sulfides and precious metal ores. The possibility of using alginate for xanthation has not been explored yet despite the feasibility by the presence of hydroxyl groups alongside the polymeric chains. Therefore, this work aims to evaluate the alginate as…[Read more]

  • Boykin Rojas posted an update 8 months ago

    Jet production and jet substructure in reactions with nuclei at future electron-ion colliders will play a preeminent role in the exploration of nuclear structure and the evolution of parton showers in strongly interacting matter. In the framework of soft-collinear effective theory, generalized to include in-medium interactions, we present the…[Read more]

  • Barbee Gissel posted an update 8 months ago

    Consequently, the PCCF takes a different liquid transport strategy with a convex-shaped advancing meniscus, differing from that on traditional conical fibers. Moreover, the as-developed PCCF is also applicable for underwater ultrafast SDLT of oil. We envision that the result will open a new perspective for fabricating a fibrous system for…[Read more]

  • Griffith Eaton posted an update 8 months ago

    05). this website The median RUNX2 and ALP expression levels were significantly higher at 2 and 4 weeks after preloading than in the unloaded condition (p less then 0.05), whereas the median RANKL/OPG ratios were significantly higher at 1 and 4 weeks after preloading (p less then 0.05). Conclusions Orthodontic preloading for 4 weeks enhances PDL…[Read more]

  • Ellegaard Kessler posted an update 8 months ago

    6ms, -5.5 beats per minute, 1.0 and 1.2ms, respectively. Despite a modest difference in heart rate, intervals were close enough to allow a detection of clinically meaningful abnormalities.

    The 6-lead hand-held device is potentially useful for a clinical follow-up of remote patients, and for a safety follow-up of patients participating in…[Read more]

  • Mccall Yildiz posted an update 8 months ago

    Background Tuberculosis (TB) unevenly affects individuals across the globe, especially in rural areas of low-income countries. Aim of the study was to assess the impact of social protection to increase TB awareness on treatment outcomes among TB patients in a rural area of Senegal. Materials & methods The study, conducted in Fimela district…[Read more]

  • Maynard Karstensen posted an update 8 months ago

    The effect of the geometric structure of artificial biomaterials on skull regeneration remains unclear. VB124 In a previous study, we succeeded in developing honeycomb β-tricalcium phosphate (β-TCP), which has through-and-through holes and is able to provide the optimum bone microenvironment for bone tissue regeneration. We demonstrated that β…[Read more]

  • Silverman Callahan posted an update 8 months ago

    Breast cancer is a remarkably complex and diverse disease. Subtyping based on morphology, genomics, biomarkers and/or clinical parameters seeks to stratify optimal approaches for management, but it is clear that every breast cancer is fundamentally unique. Intra-tumour heterogeneity adds further complexity and impacts a patient’s response to…[Read more]

  • McGarry Lodberg posted an update 8 months ago

    The value of using customized birth-weight centiles to improve the diagnostic accuracy for fetal growth restriction (FGR), in comparison with using population-based charts, remains a matter of debate. One potential explanation for the conflicting data is that most studies used measures of perinatal mortality and morbidity as proxies for…[Read more]

  • Seerup George posted an update 8 months ago

    In Thailand, almost one-quarter of strokes are related to atrial fibrillation (AF), and many could be prevented if AF were diagnosed and treated prior to the stroke. Therefore, we tested a novel strategy to screen large numbers of community residents using village health volunteers and primary care nurses.

    Local primary care nurses and…[Read more]

  • Talley Grimes posted an update 8 months ago

    © 2020 Wiley Periodicals, Inc.BACKGROUND Irritable bowel syndrome (IBS) is a common and often debilitating chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. Pharmacological treatments are often ineffective, leading to the development of a variety of behavioral interventions. Mindfulness-based stress…[Read more]

  • Carstens Garrett posted an update 8 months ago

    Different mechanisms as post-transcriptional events, epigenetics factors or protein function may be involved.

    mRNA expression is not useful as a predictor factor for the prognosis and severity of the disease. Different mechanisms as post-transcriptional events, epigenetics factors or protein function may be involved.Cerebral computed tomography…[Read more]

  • Anthony Watkins posted an update 8 months ago

    The extent of surgical intervention, also with regard to simultaneous neck dissection, depends on tumor stage. In the case of oropharyngeal carcinomas, there will be an increasing distinction between human papillomavirus (HPV)-negative and HPV-positive tumors in the future; however, the therapeutic strategy is currently identical. Upcoming…[Read more]

  • Ali Winkel posted an update 8 months ago

    Heat Stress and Supply Restriction Clearly Affect Performance, Carcass and also Beef Yield, Digestive tract Ethics, along with Inflamed (Chemo)Cytokines throughout Broiler Hens.

    influence on the velocity of tissue formation and tissue composition. The spheroids show properties that make them interesting candidates for cellular cartilage…[Read more]

  • Thygesen Frazier posted an update 8 months ago

    This work not only contributes to long-term stable operation of high-voltage LIBs but also brings new opportunities for the development of next-generation 5 V LIBs.Soft robotics focuses on mimicking natural systems to produce dexterous motion. https://www.selleckchem.com/products/1-deoxynojirimycin.html Dielectric elastomer actuators (DEAs) are an…[Read more]

  • Rouse Yildiz posted an update 8 months ago

    007). No significant association was found between the DII and anxiety and stress.

    The present study indicated that a higher DII score is associated with higher odds of depressive symptoms in men with SCI. These initial findings highlight the crucial role of the inflammatory potential of diet in the mental health of subjects with SCI. Selle…[Read more]

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