• 3 months versus 26.1 months, p = 0.005). Survival in patients with Child-Pugh A at 1, 3, and 5 years was 97%, 80%, and 73%, respectively, compared to 74%, 41%, and 31% in patients with Child-Pugh B/C. CONCLUSIONS In a small single-center cohort, patients with HCC who were denied liver transplant due to non-tumor reasons and underwent LRT and had…[Read more]

  • BACKGROUND To identify geographical clusters of suicide in São Paulo, Brazil (2006-2015) and to verify the associations of suicide with sociocultural characteristics of its 96 districts. METHODS Spatial scan test was used to detect the geographical clusters. Correlation and multiple regression techniques were used to estimate the association of…[Read more]

  • No statistically significant results were found in the meta-analysis for visfatin, nitric oxide, GSH or malondialdehyde levels or total antioxidant capacity. The data suggest that supplementation of n-3 fatty acids could reduce the inflammatory state in women with PCOS, through a decrease in hs-CRP and an increase in adiponectin…[Read more]

  • This study explored affective mechanisms of compensatory health behaviors after acting inconsistently with an important goal. Specifically, we propose and test a model in which regret over being in a situation that inhibits goal pursuit lays at the root of an individual’s engagement in compensatory behaviors such as avoiding fatty foods and…[Read more]

  • ing new interventions.

    A wealth of evidence supports short-term efficacy of lifestyle interventions in type 2 diabetes (T2D). Atezolizumab However, little is known about long-term effects of lifestyle interventions in real-life settings.

    This observational, single-arm study evaluated long-term impact of ‘Voeding Leeft…[Read more]

  • 6%) were women. Single session of Savary-Gilliard bougie dilation was successful in 90.7% of patients in relieving dysphagia and 9.3% developed recurrence, requiring repeated dilations. Four patients had concomitant squamous cell carcinoma of esophagus along with PVS and two developed upper gastrointestinal malignancy during follow-up. Conclusion…[Read more]

  • Novel therapies such as adalimumab have also been shown to be used and this shows a strong correlation with an increased number of poor prognostic factors. Reporting of these case reports and review of literature contribute to knowing more about reactive arthritis and help keep us up to date with newer therapies available when patients do not…[Read more]

  • Dalbergia sissoo DC. (Indian rosewood or Sheesham) is a traditional medicinal plant, reported since time immemorial for its analgesic, anti-nociceptive, anti-inflammatory, and immuno-modulatory properties. D. sissoo DC (DS). is being used traditionally to cure joint inflammation and joint pain.

    To study the potential of DS leaves and its…[Read more]

  • Density functional theory calculations suggest that the NHC ligands minimize unfavorable electrostatic interactions between the copper phosphide surface and H+ during the first step of the hydrogen evolution reaction, which contributes to the superior performance of NHC-ligated Cu3-xP catalysts as compared to oleylamine-ligated Cu3-xP…[Read more]

  • Black students noted, however, that harm is mitigated when online racial discrimination is challenged by their White peers. Further, findings indicated that White students may be more likely to publicly confront racist posts if they (a) are aware of the harm it causes their Black peers; (b) perceive social norms that support confronting…[Read more]

  • The posterior column osteotomy (PCO) is a tool for correction in spinal deformity. It allows for the induction of lordosis and coronal plane correction. It can be performed at multiple levels to loosen and mobilize the spine. Although the PCO does not provide as much correction as a 3-column osteotomy, it can be done in less operative time and…[Read more]

  • Bird Bell posted an update 9 months, 3 weeks ago

    The COVID-19 pandemic continues to rise. In order to control the COVID-19 pandemic, healthcare professionals have been subjected to increased exposure to work stress. In this systematic review, we aimed at investigating the prevalence and determinants of immediate and long-term post-traumatic stress disorder (PTSD) effects on healthcare…[Read more]

  • Children should be routinely asked whether they experience tinnitus and if so, they should be included in the thorough assessment and management of the condition.

    Children should be routinely asked whether they experience tinnitus and if so, they should be included in the thorough assessment and management of the condition.Background…[Read more]

  • Frailty indices may represent useful decision support tools to optimize modifiable drivers of quality and cost in neurosurgical care. However, classic indices are cumbersome to calculate and frequently require unavailable data. Recently, a more lean 5-factor modified frailty index (mFI-5) was introduced, but it has not yet been rigorously applied…[Read more]

  • Furthermore, CYP11A1, CYP17A1, and 3β-hydroxysteroid dehydrogenase type-1 gene expression levels were significantly increased in TMSCs. In bone marrow-derived and adipose tissue-derived MSCs, this differentiation method also induced the gene expression of CYP19A1, but not CYP17A1, suggesting TMSCs are a superior source for estrogen…[Read more]

  • 11 × 10-6 Ω -1 cm-1. Natural bone Hydroxyapatite gives superior results.

    Maltreated children are at high risk for low educational achievement, however few studies have accounted for confounding risk factors that commonly co-occur (including child, family and neighbourhood risk factors) and results have been mixed, particularly for a…[Read more]

  • Chronically dysregulated miRNAs (miR-451a, miR-30d-5p, miR-145-5p, miR-204-5p) are linked to psychiatric and neurodegenerative disorders. These data suggest that circulating miRNAs in biofluids can be used as “molecular fingerprints” to identify acute, chronic, focal or diffuse TBI and potentially, presence of neurodegenerative sequelae.Seipin…[Read more]

  • Seed dispersal is essential for plant recruitment and the maintenance of biodiversity. Colobine monkeys are primarily folivorous, but they also consume fruits and are often assumed to be seed predators. Although they are known to be epizoochorous seed dispersers, their role as endozoochorous seed dispersers needs reassessment. We examined…[Read more]

  • orbidity and mortality. These findings should help clinicians balance the risks and benefits of transfusion before well-designed trials are conducted in this patient population.

    Despite novel therapies, multiple myeloma (MM) remains an incurable malignancy, daratumumab (DARA) being a major game changer, may be a good option for…[Read more]

  • 0001). The VAT to SAT ratio was greater in IMR compared with HIR or FBP (both P < 0.0001).

    There are significant differences among FBP, HIR, and IMR in the volumetry of SAT and VAT, their ratios, and attenuation measured on ultra-low-dose images.

    There are significant differences among FBP, HIR, and IMR in the volumetry of SAT and VAT…[Read more]

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