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Zimmerman Eskesen posted an update 1 year ago
Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of cellular sorting processes and can drive severe physiological outcomes. Sorting nexin 27 (SNX27) is a metazoan-specific sorting nexin protein from the PX-FERM domain family and is required for endosomal recycling of many important transmembrane receptors.…[Read more]
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Sweeney Abildtrup posted an update 1 year ago
Psychological morbidity in inflammatory bowel disease is common with significant impact on quality of life and health outcomes, but factors which predict the development of psychological morbidity are unclear.
To undertake a systematic literature review of the predictors of psychological morbidity in patients with inflammatory bowel…[Read more]
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Skov Dillard posted an update 1 year ago
Univariable analysis revealed intraepithelial CD8+ cell density as the strongest predictor of endometrial cancer recurrence; multivariable analysis confirmed this was independent of pathologic factors and molecular subgroup. Exploratory analysis suggested this association was not uniform across molecular subgroups, but greatest in tumors with…[Read more]
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Pallesen Kang posted an update 1 year ago
Breast cancer is the second leading cause of death in women above 60 years in the US. Screening mammography is recommended for women above 50 years; however, 22% of breast cancer cases are diagnosed in women below this age. We set out to develop a test based on the detection of cell-free RNA from saliva. To this end, we sequenced RNA from a pool…[Read more]
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Wynn McKenna posted an update 1 year ago
Our results provide new insights into the patterns of brain evolution among animals that live under extreme conditions.The evolutionary history of organisms with poor dispersal abilities usually parallels geological events. Collisions of the Indian and Arabian plates with Eurasia greatly changed Asian topography and affected regional and global…[Read more]
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McMillan Dickens posted an update 1 year ago
The Thai medical application for patient triage, namely Triagist, is an mHealth application designed to support the pre-hospital process. However, since the functions of the application that are necessary for the pre-hospital process have been found not to be fully developed, the addition of a back-end system has been considered to increase its…[Read more]
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Irwin Bonde posted an update 1 year ago
The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a comprehensive standard for evaluating the quality of Chinese medicinal materials. The newest data from the Fourth National Survey of Chinese…[Read more]
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Compton Carlsson posted an update 1 year ago
Protein phosphatases, by counteracting protein kinases, regulate the reversible phosphorylation of many substrates involved in synaptic plasticity, a cellular model for learning and memory. A prominent phosphatase regulating synaptic plasticity and neurologic disorders is the serine/threonine protein phosphatase 1 (PP1). PP1 has three isoforms…[Read more]
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Schwartz Franks posted an update 1 year ago
A delivery service using unmanned aerial vehicles (UAVs) has potential as a future business opportunity, due to its speed, safety and low-environmental impact. To operate a UAV delivery network, a management system is required to optimize UAV delivery routes. Therefore, we create a routing algorithm to find optimal round-trip routes for UAVs,…[Read more]
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Rahbek McGarry posted an update 1 year ago
to deepen the understanding and considerations of cause-effect pathways between human activities and changes of ecosystem state through the adoption of targeted cumulative effects assessments.
Airway remodeling, as many other factors, may lead to lung function decline and irreversible airflow obstruction (IRAO) in asthma. This study was…[Read more]
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Bryan Stage posted an update 1 year ago
Hemangioma is a benign tumor made up of blood vessels and typically occurs as a slightly elevated purplish or reddish area of skin. Hemangioma is mostly found superficially; subcutaneous hemangioma in the nasal dorsum is rare.
In West Nusa Tenggara Regional Hospital, the authors found two cases of subcutaneous hemangioma in patients of…[Read more]
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Davis Dalton posted an update 1 year ago
ersensitivity and hyposensitivity.BACKGROUND Chondroblastoma (CB) is a rare locally aggressive bone tumor that commonly occurs in the epiphysis or apophysis of long bones. Although surgical treatment of CB carries potential risk for physeal or articular cartilage damage, risk factors for joint degeneration have not been well described. In…[Read more]
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Vittrup Shapiro posted an update 1 year ago
Melon necrotic spot virus (MNSV) was detected in field-grown Cucumis melo (rockmelon) and Citrullus lanatus (watermelon) plants in the Sunraysia district of New South Wales and Victoria, Australia, in 2012, 2013, and 2016, and in two watermelon seed lots tested at the Australian border in 2016. High-throughput sequencing was used to generate near…[Read more]
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Mcclure Daly posted an update 1 year ago
Although doubling the field dose (720 + 480 g ha-1) improved (5-22%) the control of these weeds in the field, split applications of both premix and tank mix provided the best control levels (≤70%), but premix treatments maintained control levels above 85% for longer (120-d). No antagonism between glyphosate and 2,4-D was found. The addition of 2…[Read more]
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Li McCain posted an update 1 year ago
INTRODUCTION AND OBJECTIVES Lack of consensus regarding how best to define treatment response hinders translation from trials to the clinic. These post hoc analyses examine three commonly used response criteria in six trials of lisdexamfetamine dimesylate (LDX) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD).…[Read more]
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Patterson Dixon posted an update 1 year ago
The addition of the ester and BHT significantly extended the induction times of the tested oils, and these compounds exhibited similar activity. Vanillyl hexanoate increased the induction time from 4.49 to 5.28 h and from 2.73 to 3.12 h in the case of rapeseed and sunflower oils, respectively.Parasitic diseases caused by ticks constitute a barrier…[Read more]
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Lorenzen Dueholm posted an update 1 year ago
The postmarketing assessment of biosimilars is important because posttranslational modification by glycosylation is altered by the manufacturing process. A retrospective study of 15 patients with gastric cancer receiving a combination anticancer therapy with trastuzumab was performed. The most common concurrent regimen was the S-1 and oxaliplatin…[Read more]
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Albert Bugge posted an update 1 year ago
Together, these six regions accounted for 90% of the total potential CO2 eq future emissions. Selleckchem Retatrutide Mangrove loss has been slowing, and global emissions could be more than halved if reduced loss rates remain in the future. Notably, the location of global emission hotspots was consistent with every dataset used to calculate…[Read more]
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Thorpe Carstensen posted an update 1 year ago
To investigate the prognostic significance of the stratification of extranodal extension (ENE) into ENE minor (ENEmi, up to 2mm) and ENE major (ENEma, over 2mm) in non-HPV-related squamous cell cancers of the head and neck, we retrospectively reviewed microscopic slides from neck dissection specimens of ENE-positive patients and subcategorised…[Read more]
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Hatch Wollesen posted an update 1 year ago
In this framework, regarding the outset, the relationships among the criteria/sub-criteria are obtained by FDEMATEL method. Then, initial weights of the criteria/sub-criteria are measured by FBWM method. Next, the final weights of criteria/sub-criteria considering the interrelationships are calculated by FANP. Finally, the performance of the…[Read more]
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