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Carlton Hopkins posted an update 8 months ago
Intravitreal administration of ADVM-022 was well tolerated and resulted in sustained aflibercept levels in ocular tissues. In addition, ADVM-022 administration 13 months before laser-induced CNV prevented the occurrence of clinically relevant CNV lesions, to the same degree as a bolus of aflibercept delivered at the time of laser. These results…[Read more]
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Suhr Crosby posted an update 8 months ago
Hence, stabilizing respiratory function may prove beneficial in improving cognitive abilities post-stroke.
The findings from our data demonstrate an association between post-stroke apnea and the development of cognitive decline, highlighting the role of aging in breathing difficulties following a cerebrovascular accident. Therefore, a focus on…[Read more]
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Vinter Egan posted an update 8 months ago
This review aimed to assess the expected course and outcome of dental bleaching procedures performed at home with bleaching products of low concentration.
This review, conducted in the style and structure of the 2020 PRISMA statement, is documented in the International Prospective Register of Systematic Reviews (PROSPERO-CRD42022360530). The…[Read more]
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Calhoun Brogaard posted an update 8 months ago
UCSF served as the conception point for children in the Child group, who were born beginning in 2001. The Pregnancy group’s enrollment period commenced in November of 2017. Parental survey responses, detailing medical histories since delivery concerning the occurrence of cardiometabolic adverse events in both parents and children, are part of the…[Read more]
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Hwang Barr posted an update 8 months ago
The FDM printing technique was employed to incorporate the material into zero-percent infill 3D-printed tablets of different configurations, manufactured at two thicknesses. Printed tablet characteristics, encompassing dimensional measurements, weight fluctuations, friability, and in vitro flotation, were determined. Both drug release and the…[Read more]
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Oneal McCracken posted an update 8 months ago
82; 95% CI 1.06 to 3.14). There is an urgent need for interventions that address the economic disenfranchisement and psychosocial problems experienced by GBM in Nigeria, which has implications for sexual health.South African children with Hodgkin lymphoma (HL) and human immunodeficiency virus (HIV) have low 5-year overall survival (OS) rates. In…[Read more]
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Borregaard Skaarup posted an update 8 months ago
Purpose In the present study, the poly (ε-caprolactone)/cellulose nanofiber containing ZrO2 nanoparticles (PCL/CNF/ZrO2 ) nanocomposite was synthesized for wound dressing bandage with antimicrobial activity. Methods PCL/CNF/ZrO2 nanocomposite was synthesized in three different zirconium dioxide amount (0.5, 1, 2%). Also the prepared…[Read more]
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Ring Hood posted an update 8 months ago
asing awareness of SRH and AFS by the government in coordination with local schools, clubs, etc. Creating an enabling environment in the service delivery sites, and ensuring privacy and confidentiality, as well as ensuring same-sex service providers and feasible service hours to adolescents, could increase the service utilization.BACKGROUND…[Read more]
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Zachariassen Griffin posted an update 8 months ago
This work aimed to assess the biomechanics, using the finite element method (FEM), of traditional titanium Morse taper (MT) dental implants compared to one-piece implants composed of zirconia, polyetheretherketone (PEEK), carbon fiber-reinforced PEEK (CFR-PEEK), or glass fiber-reinforced PEEK (GFR-PEEK). MT and one-piece dental implants were…[Read more]
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McGrath Robbins posted an update 8 months ago
Thus, to partly alleviate the noise in expression estimates, they propose a new normalization method called length-rescaled CPM. Remarkably, the authors found considerable distortions at the nucleotide level, which leads to an underestimation of diversity in transcriptome assemblies. The study by Freedman et al. (Mol Ecol Resourc 2020) clearly…[Read more]
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Bean Gray posted an update 8 months ago
We sought to identify predictors of child cytomegalovirus (CMV) infection overall and by maternal HIV status and to assess associations of child CMV status with growth and neurodevelopmental outcomes at 24 months of age in Botswana.
Data and samples were used from the Botswana-based observational Tshipidi study (2010-2014), enrolling…[Read more]
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Bigum Sivertsen posted an update 8 months ago
he molecular docking experiment confirmed the correlation between five core compounds (quercetin, stigmasterol, kaempferol, baicalein, and acacetin) just as well as PTGS2, NR3C2, CA2, and MMP1.
In this study, we described the potential active ingredients, possible targets, and key biological pathways responsible for the efficacy of XCHT in…[Read more]
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Hull Busk posted an update 8 months ago
Warangalone damages mitochondria via ROS, thereby triggering PINK1/Parkin-mediated mitophagy and inducing mitochondrial apoptosis. However, autophagy/mitophagy protects against warangalone-induced mitochondrial apoptosis. A combination of warangalone and autophagy/mitophagy inhibitors may be a potential treatment for breast cancer.Pulmonary…[Read more]
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Medlin Cain posted an update 8 months ago
Our study confirms that PD patients present deficits in cognitive components of ToM and preserved performances in the affective ones in early stages of disease. We also find a significant effect of dopaminergic therapy on ToM already after 3 months with a good persistency after 1 year of treatment.The current study, based on a survey of 1799…[Read more]
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Dam Rose posted an update 8 months ago
Low levels of phosphate in blood secondary to a lack of phosphorous reabsorption in the renal tubule cause hypophosphataemic rickets. To increase blood calcium levels, bone calcium is released into the bloodstream by increasing the activity of osteoclasts in the bones. These alterations in bone metabolism lead to delayed growth and small height,…[Read more]
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Borregaard Tennant posted an update 8 months ago
Poly acid (PLGA) targeting nanoparticles AFP/PLGA/Dt386, loaded with Dt386 plasmid of diphtheria toxin gene, modified by Alpha fetoprotein (AFP) monoclonal antibody, is prepared. Its physical and chemical properties and its effect on HepG2 cells are studied. Firstly, Dt386 expression plasmid pET11a/Dt386 is constructed and PLGA nanoparticles are…[Read more]
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Boel Hawkins posted an update 8 months ago
chain AHLs enhances current knowledge regarding the variety of AHLs produced by this enzyme. These structural data are expected to serve as a molecular rationale for AHL synthesis by AhyI.Farnesoid X receptor (FXR) agonists can reverse dysregulated bile acid metabolism, and thus, they are potential therapeutics to prevent and treat nonalcoholic…[Read more]
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Dam Salazar posted an update 8 months ago
An ability of plants memorizing past heat exposure to modulate the expression of stress response transcripts during recovery is essential for efficient acquired thermotolerance. In this study, we demonstrated that expression of heat response transcripts spiked at 30 min or 1 h, but dramatically declined at 3 h during recoveries following exposure…[Read more]
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Filtenborg Hopkins posted an update 8 months ago
Confirming previous exposure studies, the obtained data and the dietary intake assessment showed that durum wheat-based products may have a significant impact on exposure to Pb and Cd (20-50%) in the overall population, particularly in more sensitive and/or exposed subgroups (infants, toddlers, and females).Obesity is associated with autoimmunity,…[Read more]
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MacPherson Blackburn posted an update 8 months ago
The cluster analysis resulted in five clusters with differences in tinnitus pitch, lateralization, hearing thresholds and MML, as well as on age and gender. Clusters differed in contours of hearing thresholds and MML, describing patterns of low or high thresholds in combination with low or high MML. The clustering solution presented a low…[Read more]
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