-
Nedergaard Halvorsen posted an update 1 year ago
We report a case of COVID-19 in an adult single-ventricle patient post-Fontan-to our knowledge, the first report in this population documenting the use of the latest management recommendations for this novel disease. Additionally, this patient had significant pre-existing ventricular dysfunction, valvular disease, and comorbidities including HIV.…[Read more]
-
Filtenborg Horowitz posted an update 1 year ago
Two new N-acetyl-ᴅ-glucosamine derivatives, penichryfurans A (1) and B (2), were obtained from the fermentation of an endophytic fungus Penicillium chrysogenum which inhabited the marine medical red alga Grateloupia turuturu. Their structures were established by detailed spectroscopic analysis of 1D and 2D NMR in combination with HRESIMS data. T…[Read more]
-
Wulff Jackson posted an update 1 year ago
We investigated serological responses following a SARS-CoV-2 outbreak in spring 2020 on a US Marine recruit training base. 147 participants that were isolated during an outbreak of respiratory illness were enrolled in this study, with visits approximately 6 and 10 weeks post-outbreak (PO). This cohort is comprised of young healthy adults, ages…[Read more]
-
Creech Raymond posted an update 1 year ago
It is believed that, DAS has great development potential and application prospect.Mesoporous materials, especially those made of silica or silicon, are capturing great interest in the field of nanomedicine .Pneumonia is an acute pulmonary infection associated with high mortality and an immense financial burden on healthcare systems. Staphylococcus…[Read more]
-
Wilcox Maddox posted an update 1 year ago
This work explored the reliability of using points on the heart sounds envelope as indicators of the opening and closure of the aortic valve (AVO, AVC) to measure the pre-ejection period (PEP) and the left ventricular ejection time (LVET).
36 phonocardiograms (PCGs) from healthy subjects and cardiovascular disease subjects were denoised…[Read more]
-
Webster Bennetsen posted an update 1 year ago
This research provided pharmacological and chemical foundation for the application of EMS in treating rheumatoid arthritis (RA). Copyright © 2020 Wei Zhang et al.Five pulchinenosides (pulchinenoside B3, pulchinenoside BD, pulchinenoside B7, pulchinenoside B10, and pulchinenoside B11) isolated from Pulsatilla chinensis (Bge) Regel saponins extract…[Read more]
-
Sommer Stern posted an update 1 year ago
The COVID-19 pandemic underscores the need for nephrologists to be competent in serious illness communication skills that include virtual and remote modalities, to be aware of prognostic tools, and to be willing to engage with interdisciplinary teams of palliative care subspecialists, intensivists, and ethicists to facilitate goal-concordant care…[Read more]
-
Haas Spears posted an update 1 year ago
ce daily in the RA programme (0.24 (0.13-0.41)).
To characterise the safety and tolerability of nintedanib and the dose adjustments used to manage adverse events in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
In the SENSCIS trial, patients with SSc-ILD were randomised to receive nintedanib 150 mg t…[Read more]
-
Bowen Appel posted an update 1 year ago
The feeding behavior of the giant ambush-predator “Bobbit worm” (Eunice aphroditois) is spectacular. They hide in their burrows until they explode upwards grabbing unsuspecting prey with a snap of their powerful jaws. The still living prey are then pulled into the sediment for consumption. Although predatory polychaetes have existed since the…[Read more]
-
Serup Langballe posted an update 1 year ago
Southeast Asia has been the hotbed for the development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy. While mutations in the kelch propeller domain (K13 mutations) are associated with artemisinin resistance, a range of evidence suggests that other factors are critical for the establishment…[Read more]
-
Obrien Marker posted an update 1 year ago
Interviewing 67 primarily middle-class parents and children in a southern U.S. city, we learned that families know a great deal about the dangers of excess sugar consumption. However, in the private spaces of family life, families let down their guard and enjoy sugary treats, often treating them as symbolic markers of love and comfort. click here…[Read more]
-
McAllister Hines posted an update 1 year ago
Future investigation in this emerging research field may reveal how to reverse axonal injury, contributing to the development of new strategies for treating brain injuries and related neurodegenerative diseases.Ischemic stroke is one of the leading causes of global mortality and disability. It is a multi-factorial disease involving multiple…[Read more]
-
McCaffrey Panduro posted an update 1 year ago
Furthermore, we review the preclinical and clinical data of nutraceutical application against AD symptoms. Finally, we introduce new players underlying neuroinflammation in AD the activity of the endocannabinoid system and the intestinal microbiota as neuroprotectors. This review highlights the importance of a broad multimodal approach to treat…[Read more]
-
Shelton Jain posted an update 1 year ago
Glucose increased postprandial by 11.4% in the exposed group, compared with 15.7% in the other exposure group (p < 0.05), which remained significant after adjusting for confounders (- 4.7%; 95% confidence interval – 9.3%, – 0.01%). Responses to the prandial challenges for the other biomarkers did not differ by intervention group (all p &…[Read more]
-
Wilson McGinnis posted an update 1 year ago
CONCLUSION The 46TT genetype, p.Glu502Lys and p.Gly542Ser variants of the F12 gene probably underlie the low FXII level in the proband. As shown by in vitro experiment, the p.Glu502Lys and p.Gly542Ser variants can both inhibit the synthesis and secrection of the FXII protein.OBJECTIVE To analyze the clinical phenotype of six pedigrees affected…[Read more]
-
Buckley Bennetsen posted an update 1 year ago
To externally validate a Genomic Classifier (GC) based risk-stratification nomogram identifying candidates who would benefit from adjuvant radiation (aRT) therapy after radical prostatectomy (RP).
We identified 350 patients who underwent RP, between 2013 and 2018, and had adverse pathological features (positive margin, and/or pT3a or…[Read more]
-
Gupta Lykke posted an update 1 year ago
Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. To revert type 1 diabetes, the suppression of the autoimmune attack should be combined with a β-cell replacement strategy. It has been previously demonstrated that liraglutide, a glucagon-like peptide-1 receptor agonist, restores β-cell mass in ty…[Read more]
-
McFarland Ryberg posted an update 1 year ago
The emergence of various controlling strategies renders the composting products safer. Four potential removal mechanisms of ARGs in different controlling strategies have been concluded, encompassing the attenuation of selective/co-selective pressure on ARGs, killing the potential host bacteria of ARGs, reshaping the structure of bacterial…[Read more]
-
Barrera Collins posted an update 1 year ago
Xanthates are widely used in mining industry as collectors for its high affinity towards metal sulfides and precious metal ores. The possibility of using alginate for xanthation has not been explored yet despite the feasibility by the presence of hydroxyl groups alongside the polymeric chains. Therefore, this work aims to evaluate the alginate as…[Read more]
-
Boykin Rojas posted an update 1 year ago
Jet production and jet substructure in reactions with nuclei at future electron-ion colliders will play a preeminent role in the exploration of nuclear structure and the evolution of parton showers in strongly interacting matter. In the framework of soft-collinear effective theory, generalized to include in-medium interactions, we present the…[Read more]
- Load More