• Houston Sauer posted an update 1 year ago

    Furthermore, CYP11A1, CYP17A1, and 3β-hydroxysteroid dehydrogenase type-1 gene expression levels were significantly increased in TMSCs. In bone marrow-derived and adipose tissue-derived MSCs, this differentiation method also induced the gene expression of CYP19A1, but not CYP17A1, suggesting TMSCs are a superior source for estrogen…[Read more]

  • Pritchard Wind posted an update 1 year ago

    11 × 10-6 Ω -1 cm-1. Natural bone Hydroxyapatite gives superior results.

    Maltreated children are at high risk for low educational achievement, however few studies have accounted for confounding risk factors that commonly co-occur (including child, family and neighbourhood risk factors) and results have been mixed, particularly for a…[Read more]

  • Pihl Mayer posted an update 1 year ago

    Chronically dysregulated miRNAs (miR-451a, miR-30d-5p, miR-145-5p, miR-204-5p) are linked to psychiatric and neurodegenerative disorders. These data suggest that circulating miRNAs in biofluids can be used as “molecular fingerprints” to identify acute, chronic, focal or diffuse TBI and potentially, presence of neurodegenerative sequelae.Seipin…[Read more]

  • Gottlieb Moody posted an update 1 year ago

    Seed dispersal is essential for plant recruitment and the maintenance of biodiversity. Colobine monkeys are primarily folivorous, but they also consume fruits and are often assumed to be seed predators. Although they are known to be epizoochorous seed dispersers, their role as endozoochorous seed dispersers needs reassessment. We examined…[Read more]

  • Greenberg Greenwood posted an update 1 year ago

    orbidity and mortality. These findings should help clinicians balance the risks and benefits of transfusion before well-designed trials are conducted in this patient population.

    Despite novel therapies, multiple myeloma (MM) remains an incurable malignancy, daratumumab (DARA) being a major game changer, may be a good option for…[Read more]

  • Lindsay Douglas posted an update 1 year ago

    0001). The VAT to SAT ratio was greater in IMR compared with HIR or FBP (both P < 0.0001).

    There are significant differences among FBP, HIR, and IMR in the volumetry of SAT and VAT, their ratios, and attenuation measured on ultra-low-dose images.

    There are significant differences among FBP, HIR, and IMR in the volumetry of SAT and VAT…[Read more]

  • Mckinney Kamp posted an update 1 year ago

    Postactivation depression was restored when dopaminergic medication and/or deep brain stimulation was applied. Comparisons between resting and active motor states revealed that the recovery curves were similar OFF meds/OFF stim owing to faster recovery in PD seen at rest. In contrast, the effect of the motor state was different ON meds/OFF stim…[Read more]

  • Fleming Connor posted an update 1 year ago

    Triple-negative breast cancer (TNBC) has several subtypes. The identification of markers associated with recurrence and poor prognosis in patients with TNBC is urgently needed. BRCAness is a set of traits in which BRCA1 dysfunction, arising from gene mutation, methylation, or deletion, results in DNA repair deficiency. In the current study, we…[Read more]

  • Arsenault Glerup posted an update 1 year ago

    Placental extravillous trophoblast remodeling of the uterine spiral arteries is important for promoting blood flow to the placenta and fetal development. Heparin-binding epidermal growth factor-like growth factor (HB-EGF), an EGF family member, stimulates differentiation and invasive capacity of extravillous trophoblasts in vitro. Trophoblast…[Read more]

  • Monahan Howell posted an update 1 year ago

    spp. are soil bacteria that have commercial value from which numerous secondary metabolites such as antifungal compounds have been derived. There is growing concern that antifungal resistance is on the rise, and soil

    from various geographical places might produce novel antifungal molecules. The aim of this study was to characterize and…[Read more]

  • Devine Capps posted an update 1 year ago

    RESULTS Ninety-one influencing factors were identified fourteen in “dosage forms”, five in “product characteristics”, twelve in “dosage schemes”, nine in “additional instructions”, thirty-one in “patient characteristics” and twenty in “process characteristics”. CONCLUSIONS Although the findings are limited by the non-systematic search process and…[Read more]

  • Handberg Wulff posted an update 1 year ago

    Long considered a failure, second-order symmetry-adapted perturbation theory (SAPT) based on Kohn-Sham orbitals, or SAPT0(KS), can be resurrected for semiquantitative purposes using long-range corrected density functionals whose asymptotic behavior is adjusted separately for each monomer. As in other contexts, correct asymptotic behavior can be…[Read more]

  • Mahler Olsen posted an update 1 year ago

    SHANK3 is a postsynaptic scaffolding protein that plays a critical role in synaptic development and brain function. Mutations in SHANK3 are implicated in Phelan-McDermid syndrome (PMS), a neurodevelopmental disorder characterized by autistic-like behavior, delayed speech, hypotonia, and intellectual disability (ID). Moreover, mutations in SHANK3…[Read more]

  • Garrison Fletcher posted an update 1 year ago

    l and dentin was observed with nHA infiltrant compared to (as against) nanosilica infiltrant.

    The purpose of this study was to comparatively evaluate the effect of Chloroquick irrigating solution on push-out bond strength of Endoseal mineral trioxide aggregate (MTA) and endosequence root repair material (ERRM) when used as furcal perforation…[Read more]

  • Paaske Gallegos posted an update 1 year ago

    In this nested case-control study, we investigated if antiviral treatment given prior to onset of Alzheimer’s disease (AD) could influence incident AD.

    From a large population-based cohort study in northern Sweden, 262 individuals that later developed AD were compared to a non-AD matched control group with respect to prescriptions of…[Read more]

  • Stafford Guerrero posted an update 1 year ago

    Neurobiological heterogeneity in schizophrenia is poorly understood and confounds current analyses. We investigated neuroanatomical subtypes in a multi-institutional multi-ethnic cohort, using novel semi-supervised machine learning methods designed to discover patterns associated with disease rather than normal anatomical variation. Structural MRI…[Read more]

  • Ladefoged Hanson posted an update 1 year ago

    787 to 39.8 ng/mL (median 5.87 ng/mL), 0 to 2.13 ng/mL (0.347 ng/mL), and 1.98 to 82.8 ng/mL (16.6 ng/mL), respectively. Such low concentrations of paracetamol were deemed irrelevant to therapeutic effect. Based on statistical analysis, the preliminary Japanese residue limits of unhydrolyzed and hydrolyzed paracetamol were determined to be 70.5…[Read more]

  • Espensen Zacho posted an update 1 year ago

    The optimal timing of anticoagulation after stroke in patients with atrial fibrillation (AF) is unknown. We aimed to objectively assess the rate of radiological hemorrhagic transformation (HT) associated with early anticoagulation.

    A prospective, open label study (NCT04435418) of patients with AF treated with apixaban within 14days of…[Read more]

  • Parrish Aaen posted an update 1 year ago

    interchangeably for the same patient on different test sessions.PRéCIS In a case-control study, skin pigmentation was not statistically significantly different when comparing glaucoma patients to those without glaucoma.

    Darker skin color has been implicated as a risk factor for glaucoma based on previous studies’ subjective assessments of…[Read more]

  • Wu Heller posted an update 1 year ago

    The implementation of large-scale containment measures by governments to contain the spread of the COVID-19 virus has resulted in large impacts to the global economy. Here, we derive a new high-frequency indicator of economic activity using empirical vessel tracking data, and use it to estimate the global maritime trade losses during the first…[Read more]

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