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Richards Kay posted an update 1 year ago
The purpose of this review is to highlight the potential of phototherapy to deal with bacterial infections and to propose that the combination therapy strategy is an effective way to solve the challenges of single-mode phototherapy.Rationale Many viral infections are known to activate the p38 mitogen-activated protein kinase (MAPK) signaling…[Read more]
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Borregaard Kjer posted an update 1 year ago
Pre-clinical and clinical studies evidence that the inhibition of complement components results in reduced complement deposits on target and non-target tissues, and aid in recovery from the pathological conditions of ARDS. Complement inhibitors (monoclonal antibody, protein, peptide, small molecules, etc.) exhibit great promise in blocking the…[Read more]
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Foley Pacheco posted an update 1 year ago
Assaying downstream, or “higher” circuitry may provide a more sensitive measure for circuit dysfunction in mouse models of neurodevelopmental disorders.
Not applicable.
Not applicable.
Ocular siderosis is induced by a retained intraocular foreign body (IOFB) containing iron and can present as siderotic glaucoma. We report a rare…[Read more]
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Willadsen Barlow posted an update 1 year ago
Internet has become a tool of our daily lives; it can nevertheless be at health risks for excessive users. This is a global and national public health challenge, and health policy responses have been shaping up for a decade. Doctors are key players in health systems for the early detection of these disorders and for the health promotion in this…[Read more]
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Husted Skriver posted an update 1 year ago
Of those, 256 were completely removed. Clinical success was achieved in 155 individual patients (98%). Complications occurred in 6 patients 3 persistent infections, 1 stroke and 2 blood vessel ruptures. learn more The procedure-related mortality rate was 2% (n = 3). Conclusions Lead removal was associated with a high success rate and low all-cause…[Read more]
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Boel May posted an update 1 year ago
In turn, the formation of auditory regularities and proper probabilistic prediction were reflected in later components the mismatch negativity (MMNm) and the P3am, respectively. Overall, our findings reveal a hierarchy of expectations in the auditory system and highlight the need to properly account for sensory adaptation in research addressing…[Read more]
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Guthrie Galbraith posted an update 1 year ago
OBJECTIVE The orphan nuclear receptor Nur77 is an important factor regulating metabolism. Nur77 knockout mice become obese with age, but the cause of obesity in these mice has not been fully ascertained. We attempted to explain the cause of obesity in Nur77 knockout mice from the perspective of the gut microbiota and to investigate the inhibitory…[Read more]
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Poole Corcoran posted an update 1 year ago
Overdose response has become an increasingly relevant component of paramedic practice, particularly in light of increased opioid overdose globally. Previous studies have noted gaps in our understanding regarding the unique challenges which paramedics face during this form of pre-hospital emergency care. The aim of this study is to explore and…[Read more]
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Timmons Estes posted an update 1 year ago
is study highlight the value of a cognitive neuroscientific approach to research and development in the motor vehicle manufacturing industry.Background Unilateral spatial neglectis an attention disorder frequently occurring after a right-hemispheric stroke. Neglect results in a reduction in qualityof life and performance in activities of daily…[Read more]
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Hess Dillard posted an update 1 year ago
Irregular splicing was associated with tumor formation and progression in renal cell carcinoma (RCC) and many other cancers. By using splicing data in the TCGA SpliceSeq database, RCC subtype classification was performed and splicing features and their correlations with clinical course, genetic variants, splicing factors, pathways activation and…[Read more]
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Bigum Vasquez posted an update 1 year ago
82 ), prior solid tumor (OR 3.8 ) and active infection (OR 1.82 ). Further, allogeneic hematopoietic stem-cell transplantation (AlloHSCT) was performed in 8.2% in CR1. The 3-year overall survival (OS) was 34.8%. In a multivariate analysis, several factors were independently associated with a worse OS, including secondary AML (hazard ratio 2.14 )…[Read more]
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Dencker Pappas posted an update 1 year ago
Autistic individuals are at risk for developing depression though the risk and protective factors for co-occurring depression in autistic individuals are not yet fully characterized. In this retrospective medical chart review study, we explored factors associated with self-reported depressive symptoms (Patient Health Questionnaire-9) in autistic…[Read more]
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Carlton Beard posted an update 1 year ago
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide with limited treatment options. Biomarker-based active phenolic flavonoids isolated from medicinal plants might shed some light on potential therapeutics for treating HCC. 3,3′-diindolylmethane (DIM) is a unique biologically active dimer of indole-3-carbinol…[Read more]
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Melvin Hardy posted an update 1 year ago
A focal contrast enhancing lesion was still evident at the base of T2 spinous process and lung metastasis was additionally suspected. Based on histopathological, radiographic, and clinical features, an “osteoblastoma-like osteosarcoma” was suspected.
To the best of our knowledge, this is the first description of this tumour in veterinary…[Read more]
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Smart Childers posted an update 1 year ago
Highly active anti-retroviral therapy (HAART) prolongs the life span of people living with HIV (PLWHIV) and intensely reduces HIV-related morbidity and mortality. Globally, HIV-associated non-communicable diseases are becoming major public concerns, and chronic comorbidities have appeared as a substantial reason for morbidity and mortality in HIV…[Read more]
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Holst Cain posted an update 1 year ago
Protein ubiquitination, a major and conserved post-translational modification, is known to play a critical regulatory role in many biological processes in eukaryotes. Although several ubiquitinated proteins have been found in buffalo (Bubalus bubalis) testis in our previous studies, large-scale profiling of buffalo testis ubiquitome has not been…[Read more]
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Rojas Stentoft posted an update 1 year ago
Clinical providers may underestimate the role of management of diseases that can occur with obesity, termed co-morbid conditions, distinct from disease that arise as a result of obesity, co-morbidities. Many of these conditions are associated with iatrogenic weight gain, and can interfere with weight loss outcomes in children and adolescents with…[Read more]
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Chen Gammelgaard posted an update 1 year ago
Greater PTSS symptoms were related to internalizing, externalizing, rumination, and avoidant coping strategies. Coping measurement was constrained due to measurement variance, lack of developmentally and contextually vali-dated instruments, theoretical misalignment, and absence of comprehensive tools to assess coping. Robust and consistent…[Read more]
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Bigum Blackburn posted an update 1 year ago
a large economic benefit to Ugandan society. Overall, the results of the study support increasing pediatric surgical capacity in rural areas of low- and middle-income countries through support and training of general surgeons and anesthesia providers.It is currently well established that more than half of heart failure patients have preserved…[Read more]
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Bass Schulz posted an update 1 year ago
n thermal recycling of brominated flame retardants (BFRs).On the basis of the metabolic synergy between autotrophic denitrification (AuDen) and anaerobic ammonium oxidation (Anammox), the feasibility of a novel ferrous sulfide (FeS)-driven AuDen and Anammox coupled system (FS-DADAS) was investigated. The nitrogen removal performance of FS-DADAS…[Read more]
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