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Thygesen Rye posted an update 1 year ago
Survival rates were analyzed by the Kaplan-Meier method. Results Postoperatively 23 patients received radiotherapy and 13 patients received chemoradiotherapy. All patients were followed up for more than 3 years. Total 3-year and 5-year survival rates were 60.5% and 49.0%, respectively. Patients obtaining the conservation of laryngeal functions…[Read more]
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Egan Purcell posted an update 1 year ago
Administration of ECa 233 was found to be significantly associated with an increase of choline, an endogenous metabolite with documented benefits for learning and memory. Therefore, ECa 233 may be useful in mitigating cognitive impairment, through its role in modulating human metabolites.The rapid spread of the Coronavirus (COVID-19) confronts…[Read more]
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Cramer Edwards posted an update 1 year ago
CONCLUSIONS Our results suggest that EA suppresses pain and pain-related anxiety-like behavior of chronic inflammation in rats by increasing the expression of the NPS/NPSR system in the ACC. AIMS Bilateral absence of cortical somato-sensory evoked potentials (SSEPs) robustly predicts poor outcome after cardiac arrest (CA), but it is uncertain if…[Read more]
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Peck Gay posted an update 1 year ago
All patients who received the complement blocker eculizumab in addition to the interferon gamma blocker emapalumab had complete resolution of their TMA and survived. Our observations suggest co-activation of both interferon and complement pathways as a potential culprit in the evolution of thrombotic microangiopathy in patients with inflammatory…[Read more]
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Skaarup Dogan posted an update 1 year ago
We analyze the biomechanical consequences of acute rotator cuff tears along with characteristic mechanism of injury and spectrum of tendon involvement. The evolving concepts in the diagnosis and management of these distinct injuries are discussed with review of current literature.Pain is a result of nociceptive tissue injury and results in acute…[Read more]
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Houston Randolph posted an update 1 year ago
More importantly, using a natural occurring retinal degeneration model caused by a nonsense mutation of Phosphodiesterase 6b gene (Pde6bmut), we confirmed that MSCT and EXOT prevented photoreceptor loss and protected long-term retinal function. In deciphering therapeutic mechanisms regarding potential exosome-mediated communications, we identified…[Read more]
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Williamson Giles posted an update 1 year ago
Several studies have demonstrated that coronary heart disease (CHD) is a high risk factor for cognitive impairment, whereas other studies showed that there was no association between cognitive impairment and CHD. The relationship between CHD and cognitive impairment is still unclear based on these conflicting results. Thus, it is of importance to…[Read more]
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Franks Schaefer posted an update 1 year ago
The analysis was carried out from a model that presents a broad and complex view of science, as it addresses several areas of knowledge and specific aspects of each of them and proposes the generation of one’s view of science from an integration of some of its distinct areas and/or aspects. The results show the current pandemic is a rich…[Read more]
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Karstensen Bonde posted an update 1 year ago
The globally increasing resistance due to extended-spectrum beta-lactamase producing
is a major concern. The objective of this work was to develop a murine model to study the gut bacteria parameters during complex antibiotics like cefotaxime and ceftriaxone treatment and to compare the fecal carriage of ESBL-producing
.
SWISS…[Read more]
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Storm Camacho posted an update 1 year ago
Agonist evoked platelet activation results in intracellular Zn2+ (i) fluctuations that are sensitive to the platelet redox state. Increases in i correlate with activation responses, including shape change, granule release, αIIbβ3 activation and phosphatidyl-serine exposure, consistent with a role as a second messenger. This review provides i…[Read more]
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Sonne Lu posted an update 1 year ago
Physiological imbalance is an abnormal physiological condition that cannot be directly observed but is assumed to precede subclinical and clinical diseases in the beginning of lactation. Alert systems to detect the physiological imbalance in a cow using Fourier transform mid-infrared spectroscopy in milk have been developed. The objective of this…[Read more]
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McCormack Stroud posted an update 1 year ago
10 (1.03-1.17) at 30 years, 1.11 (1.04-1.17) at 50 years and 1.19 (1.10-1.29) at baseline. The results for women were similar with multivariable RR of 1.16 (1.06-1.27) at 30 years, 1.14 (1.05-1.24) at 50 years and 1.11 (0.99-1.24) at baseline.Conclusion These findings suggest that high load of OPA previous in life may play a role in increasing the…[Read more]
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Dalgaard Tolstrup posted an update 1 year ago
d the malignant behaviors of ESCC cells but also induced EMT and CAFs transformation. Our studies suggested an oncogenic role of LTBP1 in ESCC progression and it may serve as a potential therapeutic target for ESCC patients.BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with poor prognosis and a significant…[Read more]
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Barrera Erichsen posted an update 1 year ago
Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive multiple congenital malformation and intellectual disability syndrome resulting from variants in DHCR7. Auditory characteristics of persons with SLOS have been described in limited case reports but have not been systematically evaluated. The objective of this study is to describe the…[Read more]
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Buckner Horn posted an update 1 year ago
Background Teenage pregnancy rates are falling in many high-resource settings, but for those who do conceive, the socioeconomic and educational disadvantage that ensues is often long lasting and intergenerational. The adverse maternal and neonatal outcomes can be ameliorated through antenatal and postnatal care that attends to the special needs of…[Read more]
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Riddle Bigum posted an update 1 year ago
These predicted target genes were further analyzed by function annotation and enrichment pathways, the results showed that these targets of the identified miRNAs are involved in a broad range of physiological functions.Introduction Conservative management of primary obstructive megaureter (POM) appears as the best option in patients with adequate…[Read more]
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Lindgren Barton posted an update 1 year ago
Thanks to the great flexibility brought by unpaired training, EnlightenGAN is demonstrated to be easily adaptable to enhancing real-world images from various domains. Our codes and pre-trained models are available at https//github.com/VITA-Group/EnlightenGAN.Benefiting from the strong capabilities of deep CNNs for feature representation and…[Read more]
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Mcintyre Hewitt posted an update 1 year ago
Automated detection of atrial fibrillation (AF) in continuous rhythm registrations is essential in order to prevent complications and optimize treatment of AF. Many algorithms have been developed to detect AF in surface electrocardiograms (ECGs) during the past few years. The aim of this systematic review is to gain more insight into these…[Read more]
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Saunders Roth posted an update 1 year ago
actice. Some survey responses possibly reflect ambiguity in doctors’ intentions when providing medication. SAR405 order This article is protected by copyright. All rights reserved.
COVID-19 is known to cause an acute respiratory illness, although clinical manifestations outside of the respiratory tract may occur. Early reports have identified…[Read more]
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Covington Brodersen posted an update 1 year ago
Background Cancer is one of the deadliest diseases at present. Although effective screening and treatment can save lives to a certain extent, our knowledge of the disease is far from sufficient. KIF18B is a member of the kinesin-8 superfamily and plays a conserved regulatory role in the cell cycle. KIF18B reportedly functions as an oncogene in…[Read more]
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