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Thrane McKay posted an update 1 year ago
s conclusion was low. For second-generation quinolones and co-trimoxazole, single-dose regimen was less effective than 3-day regimen in clinical response, with moderate quality of evidence. Interpretation Treatment duration of the third-generation and fourth-generation quinolones and pivmecillinam could be shorter than the currently recommended…[Read more]
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Archer Morris posted an update 1 year ago
REB accumulation in the cheek pouch of hamsters treated with the R-NPs gel was prevented by an inhibitor of clathrin-dependent endocytosis (CME) (40 μM dynasore). In conclusion, we designed an R-NPs gel and found that REB nanocrystals are taken up by tissues through CME, where they provide a persistent effect resulting in an enhancement of oral…[Read more]
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Marcus Turan posted an update 1 year ago
Active bleeding within the gastrointestinal (GI) system is arrested by a topical hemostatic powder, which creates an adhering barrier. The Food and Drug Administration (FDA) in the United States has formally recognized Hemospray as the pioneering hemostatic powder to receive their approval. Gastrointestinal bleeding management is increasingly…[Read more]
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Burris Stein posted an update 1 year ago
There has recently been an increasing interest in local field potential (LFP) for brain-machine interface (BMI) applications due to its desirable properties (signal stability and low bandwidth). LFP is typically recorded with respect to a single unipolar reference which is susceptible to common noise. Several referencing schemes have been proposed…[Read more]
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Hyldgaard Kinney posted an update 1 year ago
0491). Additionally, right-sided tumors had a higher predisposition to be a luminal-A subtype of IBrC (p = 0.0016). Furthermore, 10% of left-sided tumors exhibited an overexpression of HER2, while only 2% patients suffering right-sided tumors displayed a positive score (p = 0.0357). Our findings revealed a significantly higher concentration of…[Read more]
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Andreassen From posted an update 1 year ago
This shows that the neural progenitors retain their cellular self-organization ability in the FN-silk/LN-521-supported 3D culture. Calcium imaging demonstrated spontaneous activity, which is important for the formation of neuronal networks. Together, the results show that hPSCs integrated into FN-silk/LN-521 foam develop into neural progenitors…[Read more]
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Whitley Jokumsen posted an update 1 year ago
9 percentage point increase in the likelihood of avoided care owing to cost (95% CI=1.7, 16.2), a 10.4 percentage point decrease in the likelihood of mammogram receipt during the past 12 months (95% CI= -22.3, 1.5), and a 12.5 percentage point decrease in the likelihood of ever receiving a clinical breast examination (95% CI= -18.7, -6.3). Driving…[Read more]
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Hvid Lamb posted an update 1 year ago
Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. Consequently, this build-up could lead to several complications such as nearsightedness, dislocated eye lenses, a variety of…[Read more]
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Hjelm Donovan posted an update 1 year ago
Modern western diets have been associated with a reduced proportion of dietary omega-3 fatty acids leading to decreased levels of DHA (docosahexaenoic acid) in the brain. Low DHA content has been associated with altered development of visual acuity in infants and also with an altered time course of synapse elimination and plasticity in subcortical…[Read more]
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Morton Washington posted an update 1 year ago
In addition, the influence of different latitudinal climate zones on the distribution of elements in the atmospheric deposition was observed. The enrichment factor shows considerable values for Th and Zr. The spatial distribution of the pollution load index identifies four zones (#12, 38, 53, and 64). The potential ecological risk index and the…[Read more]
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Tuttle Malling posted an update 1 year ago
Once the diagnosis is confirmed we retrospectively analyzed the etiology, clinical features, management and outcomes of renal transplant recipients with pancreatitis. RESULTS Twenty-six patients (men 81%; mean age 38.5 years) were included. Etiology included gallstones (19.3%), structural lesions (11.5%), viral infections (7.8%), and drugs.…[Read more]
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Svenningsen Griffith posted an update 1 year ago
Severe losses in aquacultured and wild hard clam (Mercenaria mercenaria) stocks have been previously reported in the northeastern United States due to a protistan parasite called QPX (Quahog Parasite Unknown). Previous work demonstrated that clam resistance to QPX is under genetic control. This study identifies single nucleotide polymorphism (SNP)…[Read more]
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Korsgaard Rye posted an update 1 year ago
These observations underscore the importance of the inter-population molecular heterogeneity of prostate cancer. In addition, we examined the expression of UGT2B4 in 497 prostate cancer patients derived from The Cancer Genome Atlas database. We found that high expression of UGT2B4 was associated with low-grade prostate cancer and upregulation of…[Read more]
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Ernstsen Duke posted an update 1 year ago
Among the 130 selected studies, nine papers were included for quantitative synthesis. The quality-appraisal was good for two, fair for three and poor for four studies. The pooled relative risk (RR) of SVR12 was not statistically different between decentralized strategy and treatment by specialists . SVR12 rate for decentralized HCV treatment was…[Read more]
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Haney Bugge posted an update 1 year ago
Pharmacists play an important role in the healthcare system and have a greater impact on the outcome of public health programs. Patients who seek nutrition and vitamin advice presume the role of community pharmacists including the recommendation of effective vitamin and nutritional products.
To determine the knowledge, attitudes, and…[Read more]
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Kilgore Hsu posted an update 1 year ago
e., no evidence of winner’s curse). Meta-regressions indicated consistent effects for neuroticism, openness, and conscientiousness across methods to assess dementia, dementia type, follow-up length, sample age, minority, country, and personality measures. The association of extraversion and agreeableness varied by country. Our findings indicate…[Read more]
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Ali Fleming posted an update 1 year ago
14 (95% CI 0.88-1.48). The leading causes of death were cardiovascular diseases (CVDs) (33%), malignancies (27%) and neurological diseases (10%). Subhazard ratio for CVD deaths was 1.28 (95% CI 0.85-1.93), adjusted for comorbidities and education 0.88 (95% CI 0.56-1.39).
These results suggest that the increased mortality in SLE patients is…[Read more]
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Dam Salazar posted an update 1 year ago
Infarct size was measured using tetrazolium staining. Results Ischaemia and reperfusion respectively reduced and increased mitochondrial QO2 (state 3) and the ox-phos rate in both control and HFSD mitochondria, showing no major changes between the groups, while melatonin pretreatment had little effect. p62 as indicator of mitophagic flux showed…[Read more]
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Richards Stilling posted an update 1 year ago
Of the total number of recommendations, 60% had no accompanying citation and 28% of recommendations provided citations that did not directly support the statement made. Additionally, 52% of included documents did not state the methods of document development. That is, it was not clear if there was a literature review and/or expert consensus that…[Read more]
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Shapiro Deal posted an update 1 year ago
004), hemoglobin level (β = – 0.40, p = 0.001) and LV mass index (β = 0.24, p = 0.03) were determinants for resting coronary flow velocity. On the other hand, age (β = -0.30, p = 0.008), hemoglobin level (β = -0.47, p less then 0.001) and LV mass index (β = 0.24, p = 0.04) were determinants for hyperemic coronary flow velocity. Age was only dete…[Read more]
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