• This study was the first to evaluate the possible protective effects of cinnamic acid (CA) against Gentamicin (GM) induced liver and kidney dysfunctions in rats. Adult male Wistar rats were randomly assigned to 4 equal groups (n = 8) Control group (saline, 0.5 ml/day), CA group (CA, 50 mg/kg/day), GM group (GM, 100 mg/kg/day), and GM + CA group…[Read more]

  • 001 for both comparisons) and serum sclerostin 30.9 ± 31.9 vs 26.9 ± 21.1 pmol/L (p = 0.516). Positive correlation was found between BIA and DXA SMI × Baumgartner (r = 0.842; p  less then  0.001) and fat mass (r = 0.970; p  less then  0.001). Gait speed was relatively preserved in sleeve gastrectomy (SG) compared with Roux-en-Y gastric bypass…[Read more]

  • This work aims at fabricating 5-fluorouracil (5-FU)-loaded poly (lactic-co-glycolic) acid nanoparticles (PLGA NPs) using a microfluidic (MF) technique, with potential for use in colorectal cancer therapy. In order to achieve 5-FU-loaded NPs with an average diameter of approximately 119 nm, the parameters of MF process with fork-shaped patterns…[Read more]

  • Linc-ROR is reported to be a potential biomarker of breast cancer, but the detailed mechanism of linc-ROR-mediated breast cancer regulation has not been fully studied. We aimed to explore how linc-ROR affects proliferation, metastasis and drug sensitivity in breast cancer. Cell lines in which linc-ROR was overexpressed or knocked down were…[Read more]

  • Large-cell neuroendocrine carcinomas (NECs) of the colon are extremely rare aggressive tumors. A 79-year-old man presented at our hospital for muco-hematic diarrhea, weight loss and incarcerated hernia in his left groin. Colonoscopy revealed sigmoid stenosis. Computed tomography confirmed an incarcerated hernia containing sigmoid mass and massive…[Read more]

  • Moreover, hand and respiratory hygienic along with the risk of infection also significantly contributing to minimizing the pandemic outbreak.

    The diagnosis of lung cancer (LC) may be difficult to make in the elderly. We report on the diagnostic elements available in life in an LC necropsy case series of asbestos-exposed workers and describe…[Read more]

  • Suicidal behavior is a globally widespread psychiatric disorder with a high rate of mortality. Suicide causes psychological and economic hardships for the families and societies, necessitating the development of effective prevention and treatment programs. However, a clear understanding of the neural basis of suicidal behavior would be essential…[Read more]

  • Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) amplification of Sars-CoV-2 virus RNA extracted from oro/nasopharyngeal swabs. Despite the good specificity of the assays certified for SARS-CoV-2 molecular detection, and a…[Read more]

  • Responses from participants with working-class occupations tended to be characterised by elevated endorsements of coping motives.

    Drinking motives are stronger predictors of problem alcohol consumption than socio-demographic variables although these factors exert influences on people’s motives to drink.

    Drinking motives are stronger…[Read more]

  • © The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email journals.permissions@oup.com.Neural cell adhesion molecule 2 (NCAM2) is involved in the development and plasticity of the olfactory system. Genetic data have implicated the NCAM2 gene in neurodevelopmental disorders including Down…[Read more]

  • The proof-of-concept experiments illustrate the viability of the constant pressure mode of operation for the second dimension of 2D-LC. In the described separations the throughput improvement is on the order of 10%; this gain will be strongly application-dependent, and may be as large as several tens percent in some cases. Future work will involve…[Read more]

  • Worldwide, one in three women have experienced sexual violence, causing various physical and mental health problems such as depression, posttraumatic stress disorder and medically unexplained symptoms. Much has changed in the last decade. The use of the Internet, smartphones and apps has increased enormously, sexual violence is discussed more and…[Read more]

  • Moreover, high-throughput 16S rRNA gene sequencing indicated that nano-size MPs significantly inhibited phenanthrene-degrading bacteria in earthworms, resulting in the highest residual concentration of phenanthrene. This study highlights the size effects of MPs and their impacts on the accumulation of organic pollutants by terrestrial…[Read more]

  • aureus and P. aeruginosa were examined. In vitro cytocompatibility was successfully tested on pure, reduced, and PEG immobilized samples.Estrogen receptor signaling plays.The present work has undertaken a meticulous glance on optimizing the performance of an SGMD configuration utilized a porous poly (vinylidene fluoride-co-hexafluoropropylene)…[Read more]

  • 80±0.17) but increased for 15 mm (0.85±0.22, p = 0.024) and were located mostly laterally, close to the condylar center. This study confirmed higher reduction of TMJ space on the balancing than on the working condyle during mastication. Intra-articular distances increased significantly for the greatest bolus thickness. Loaded areas were located l…[Read more]

  • been promoted by the revised Health Promotion Act. It is, thus, necessary to monitor the situation of exposure to secondhand smoke at the workplace across diverse settings.Objectives One of the diversity indicators of food intake in the elderly Japanese population is the Dietary Variety Score (DVS). Studies on elderly people have reported the r…[Read more]

  • Protein disulphide isomerase (PDI) and NADPH oxidase 1 (Nox-1) regulate platelet function and reactive oxygen species (ROS) generation, suggesting potentially interdependent roles. Increased platelet reactivity and ROS production have been correlated with cardiometabolic disease risk factors.

    To establish whether PDI and Nox-1 cooperate to…[Read more]

  • 7%). PID patients are at high risk of developing fungal infections.This study aimed to investigate the feasibility of preparing a hydrogel based on (OMePhSe)2-loaded poly(Ɛ-caprolactone) nanocapsules using carrageenan gum as a gel-forming agent. Furthermore, the anti-inflammatory action of hydrogel was assessed in an animal model of skin lesion…[Read more]

  • Patients exposed to chronic sustained hypoxia frequently develop cardiovascular disease risk factors to ultimately succumb to adverse cardiovascular events. In this context, the present study intends to assess the role of cilnidipine (Cil), a unique calcium channel blocker that blocks both L-type and N-type calcium channels, on cardiovascular…[Read more]

  • Neurosarcoidosis is a rare systemic disorder that can affect the eye and other organs, including the central nervous system. Neurosarcoidosis infiltrating the optic nerve presenting as central retinal vein occlusion combined with artery ischaemia has not been reported in the literature previously. We describe a Chinese patient presenting with…[Read more]

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