• specific age groups (i.e., younger than 10 years and older than 75-80 years) and swimming strokes in pool-swimming or even to overperform men in long-distance open-water swimming (distance of ~30 km), especially under extreme weather conditions (water colder than ~20 °C). Two main variables may explain why women can swim faster than men in…[Read more]

  • We highlight six behaviour change techniques especially suited to disrupting habit associations, but show that these techniques have been underused in weight loss maintenance interventions to date. We call for intervention developers and practitioners to adopt techniques conducive to forming new habit associations to directly override old habits,…[Read more]

  • In patients with primary biliary cholangitis (PBC), the efficacy of budesonide, a synthetic corticosteroid displaying high first-pass metabolism, is unresolved. In a placebo-controlled, double-blind trial, we evaluated the added-value of budesonide in those with PBC and ongoing risk of progressive disease despite ursodeoxycholic acid (UDCA)…[Read more]

  • Finally, I present a perspective on the evolutionary link between phenotypic switching and the origin of multicellularity.SARS-CoV-2 led to considerable morbidity/mortality worldwide and tremendously impacted on daily life. Strict lockdown measures were implemented early to contain the viral outbreak in Austria. Massive changes in organizational…[Read more]

  • The proximity of the orofacial structures to the upper airway has led to enormous interest in their influence on the airway maintenance mechanism. The recognition of Sleep disorders and the evolution of dental sleep medicine has fueled further interest in the role of orthodontic treatment on the airway particularly in Class II malocclusions. learn…[Read more]

  • (Am J Public Health. Published online ahead of print March 19, 2020 e1-e6. doi10.2105/AJPH.2019.305561).Cardiofaciocutaneous (CFC) syndrome is a rare condition characterized by congenital heart disease, craniofacial dysmorphology, and dermatological abnormalities. CFC syndrome is one of the RASopathies, a family of syndromes that also includes…[Read more]

  • Single-molecule localization microscopy (SMLM) enabling the investigation of individual proteins on molecular scales has revolutionized how biological processes are analysed in cells. However, a major limitation of imaging techniques reaching single-protein resolution is the incomplete and often unknown labeling and detection efficiency of the…[Read more]

  • Polymer foams are an essential class of lightweight materials used to protect assets against mechanical insults, such as shock and vibration. Two features are important to enhance their energy absorption characteristics the foam structure and the matrix phase mechanical behavior. This study investigates novel approaches to control both of these…[Read more]

  • Water availability is a main limiting factor for plant growth, development and distribution throughout the world. Stomatal movement mediated by abscisic acid (ABA) is particularly important for drought adaptation, but the molecular mechanisms in trees are largely unclear. Here, we isolated an ABA-responsive element binding factor PeABF3 in Populus…[Read more]

  • 55 vs 3.76, P < .001; 3.55 vs 3.80, P= .001; 3.55 vs 3.99, P < .001). The pediatric asthma impact survey scores improved from baseline to visits 2 and 3 (43.33 vs 34.08, P < .001; 43.33 vs 31.74, P < .001). ED visits and prednisone use significantly decreased from baseline to visits 2 and 3 (ED 0.46 vs 0.13, P= .03; 0.46 vs 0.02, P= .02;…[Read more]

  • Circular RNAs (circRNAs) play vital roles in various types of cancer and chemosentivity. In the progression of carcinogenesis, exosomes are messengers for intercellular communication. The aim of this study was to explore the role of exosomal circRNA phosphatidylinositol-4-phosphate 5-kinase type 1 alpha (circ_PIP5K1A) in non-small cell lung cancer…[Read more]

  • Notably, our modeling did not support achieving herd immunity as a practical objective, requiring an unlikely balancing of multiple poorly defined forces. learn more Specifically, we found that 1) social distancing must initially reduce the transmission rate to within a narrow range, 2) to compensate for susceptible depletion, the extent of social…[Read more]

  • The most noteworthy mechanisms were those that minimized participation (especially, attributing behavior to obeying orders displacement of responsibility) and moral justification, especially, the context of confrontation. Moral disengagement processes are found in armed group members (such as insurgency, terrorist organizations, or militias).…[Read more]

  • Introduction Although figure skating attracts several hundred thousand participants worldwide, there is little knowledge about physical health and sports injuries among young skaters. The present study aimed to describe the health status of a geographically defined Swedish population of licensed competitive figure skaters and to examine injury…[Read more]

  • Mentors and mentees must weigh the relevance of COVID-19 research projects to the postpandemic world and the amount of available funding against the developing interests of early career investigators. Academic medical centers nationwide must enable seasoned and early career researchers to contribute meaningfully to COVID-19 and non-COVID-19…[Read more]

  • Recently an increasing number of new adenovirus types associated with type-dependent pathogenicity have been identified. However, identification of these clinical isolates represents the very first step to characterize novel pathogens. For deeper analyses, these adenoviruses need to be further characterized in basic virology experiments or they…[Read more]

  • in the paediatric settings, supporting the value of future research in this field.

    Glutamine supplementation has been applied clinical practice to treat inflammatory bowel disease (IBD). However, scientific evidence about this is still controversial.

    In this review, we systematically evaluated the effects of glutamine supplementation…[Read more]

  • Studies demonstrate a role for the bed nucleus of the stria terminalis (BNST) in modulating affective behavior and stress-reward integration. To explore the dynamic nature of in vivo BNST activity associated with anxiety-like behavior in a stress-inducing context, we utilized fiber photometry and detected BNST calcium transients in mice during the…[Read more]

  • The C/T-13910 LCT is closely associated with lactase persistence and LCT has emerged as a new candidate gene for obesity, in particular in northern Europeans. The aim of this research is to investigate to what degree sex determines the association between the LCT variant and anthropometric traits in a cohort of healthy individuals. We recruited…[Read more]

  • Lake Oneal posted an update 8 months, 1 week ago

    day 7 after TBI were reduced by necrostatin-1-containing regimens; however, normalization of plasma protein levels at day 7 required the addition of JP4-039 and baicalein. These findings indicate that mitigator targeting to three distinct cell death pathways increases survival after TBI.Vitamin B12 and propionic acid that were simultaneous…[Read more]

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