• Zachariassen Kamp posted an update 1 year ago

    powerment will be increased which will certainly increase happiness.Restoration of agricultural drylands globally, here farmlands and grazing lands, is a priority for ecosystem function and biodiversity preservation. Natural areas in drylands are recognized as biodiversity hotspots and face continued human impacts. Global water shortages are…[Read more]

  • Hussain Stafford posted an update 1 year ago

    In some patients securing the peripheral intravenous cannula (PIVC) with a standard adhesive dressing can be difficult because of sweat or other body fluids. The aim of our study was to evaluate the use of tissue adhesives alone as a means to secure PIVCs inserted in the emergency department.

    We performed a prospective interventional pilot…[Read more]

  • Greve Due posted an update 1 year ago

    Liver cancer is a critical clinical condition with augmented malignancy, rapid progression, and poor prognosis. Liver cancer often initiates as fibrosis, develops as cirrhosis, and results in cancer. For centuries, medicinal plants have been incorporated in various liver-associated complications, and recently, research has recognized that many…[Read more]

  • Richmond Velazquez posted an update 1 year ago

    4-phenylbutyric acid (4-PBA) is a low molecular weight fatty acid that is used in clinical practice to treat inherited urea cycle disorders. In previous reports, it acted as a chemical chaperone inhibiting endoplasmic reticulum (ER) stress and unfolded protein response signaling. A few studies have suggested its function against hepatic fibrosis…[Read more]

  • Donaldson Wilkins posted an update 1 year ago

    To synthesize evidence on the association between human immunodeficiency virus (HIV) infection and cognitive impairment in older adults.

    Meta-analysis.

    Adults aged 50 years or older.

    In this systematic literature review and meta-analysis, we searched PubMed, Scopus, Embase, and APA/PsycNet for studies published before July…[Read more]

  • Berthelsen Horton posted an update 1 year ago

    Impaired circulating estrogen levels have been related to impaired glycemic homeostasis and diabetes mellitus (DM), both in females and males. However, for the last twenty years, the relationship between estrogen, glycemic homeostasis and the mechanisms involved has remained unclear. The characterization of estrogen receptors 1 and 2 (ESR1 and…[Read more]

  • Hede Reddy posted an update 1 year ago

    Knocking down LCN2 enhanced the radiosensitivity of NPC cells by impairing their ability to repair DNA damage or proliferate, while ectopic expression of LCN2 conferred additional radioresistance to NPC cells. Immunohistochemical analysis of 100 NPC specimens revealed that LCN2 expression was significantly upregulated in radioresistant NPC tissues…[Read more]

  • Reddy Espersen posted an update 1 year ago

    These results exhibit different hydration environments for the causative and protective mutants highlighting the differential roles of charge and hydrophobicity.Curcumin, a molecule of labile natural product, has multiplex pharmacological effects, including antioxidant, antimicrobial, and anticancer effects as well as anti-Alzheimer’s disease (AD)…[Read more]

  • Hatfield Lamm posted an update 1 year ago

    Biologic drugs have significantly improved the treatment of ulcerative colitis (UC) and Crohn’s disease (CD). However, the availability of these drugs is limited by their high cost. Infliximab was the first biologic to be approved for inflammatory bowel diseases (IBD). After its patent expired other manufactures developed biosimilar versions,…[Read more]

  • Butcher Fog posted an update 1 year ago

    Ponatinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia and acute lymphoblastic leukemia. Common adverse effects of ponatinib include neutropenia, arterial thrombosis, and hypertension. We describe a 49-year-old woman who developed panniculitis after brief treatment…[Read more]

  • Haley Henderson posted an update 1 year ago

    Based on our findings and a review of literature we propose a classification of SB subtypes in SB occulta and the 3 SBA subtypes, meningocele, myelomeningocele, and myeloschisis.The bug Orius similis Zheng is a native generalist predator of insect pests in southern China. The fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith), is a notorious…[Read more]

  • Welch Stephens posted an update 1 year ago

    We review the current technology underlying surface haptics that converts passive touch surfaces to active ones (machine haptics), our perception of tactile stimuli displayed through touch surfaces (human haptics), their potential applications (human-machine interaction), and finally the challenges ahead of us in making them available through…[Read more]

  • Huffman Vinding posted an update 1 year ago

    Hydatid disease is a major health problem worldwide. The liver is the most frequent location of hydatid disease. Acute pancreatitis secondary to liver hydatid cyst ruptured in the biliary tract is scarce and fewly described in literature. The management of this pancreatic complication of liver hydatid disease is challenging and includes a…[Read more]

  • Wooten Murdock posted an update 1 year ago

    Open research data provides considerable scientific, societal, and economic benefits. However, disclosure risks can sometimes limit the sharing of open data, especially in datasets that include sensitive details or information from individuals with rare disorders. This article introduces the concept of synthetic datasets, which is an emerging…[Read more]

  • Mead Brandt posted an update 1 year ago

    In conclusion, there may be an increased risk of injury withthe non-dominant leg due to changes in kinematic parameters caused by fatigue and unpredictable CoD manoeuvres.Slowed processing speed is part of normal aging but also a symptom of many diseases, including dementia. A Quick Test of Cognitive Speed (AQT) consists of three conditions color…[Read more]

  • Mccall Kejser posted an update 1 year ago

    Class D β-lactamases have risen to notoriety due to their wide spread in bacterial pathogens, propensity to inactivate clinically important β-lactam antibiotics, and ability to withstand inhibition by the majority of classical β-lactamase inhibitors. Understanding the catalytic mechanism of these enzymes is thus vitally important for the de…[Read more]

  • Lamb Prince posted an update 1 year ago

    We provide an overview of each protocol and discuss their applicability. We also review recent benchmarking studies comparing each protocol’s performance and summarize the major conclusions that can be gathered from their usage. The result documents variable performance of the protocols and highlights their different applications in miRNA…[Read more]

  • Gilliam Brantley posted an update 1 year ago

    Lead halide perovskite (APbX3) nanocrystals exhibit photoluminescence (PL) with both wide wavelength tunability and high quantum efficiency. While the Pb-X6 octahedra mainly determines the near-band-edge optical properties and the A-site cation affects the structural stability, the role of the A-site cation in determining the optical properties is…[Read more]

  • Oconnor Lester posted an update 1 year ago

    Radiation therapy has benefited from many developments over the past 20 years. These developments are mainly linked to the technology, imaging and informatics evolutions which allow better targets definitions, ensure better organs-at-risk sparing and excellent reproducibility of treatments, with a perfect control of patient positioning. In breast…[Read more]

  • Mosegaard McCarty posted an update 1 year ago

    Revascularization of the coronary arteries, via open sternotomy and on cardiopulmonary bypass, remains the most common cardiac surgical procedure in the United States. Patients, and cardiologists, seek an alternative to dividing the sternum while reaping the advantages of left internal mammary artery (LIMA) revascularization of the diseased left…[Read more]

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