• Meanwhile, the protein expression of LC3 was increased in cells treated with 10 and 100 ng/ml FSH. 1 and 10 ng/ml FSH significantly increased E2 production, whereas 10 and 100 ng/ml FSH significantly increased P4 production. FSH significantly inhibited the phosphorylation of AKT in cells treated with higher concentrations (1, 10 and 100 ng/ml),…[Read more]

  • Anion…π interactions are newly recognized weak supramolecular forces which are relevant to many types of electron-deficient aromatic substrates. Being less competitive with respect to conventional hydrogen bonding, anion…π interactions are only rarely considered as a crystal-structure-defining factor. Their significance dramatically i…[Read more]

  • 83%. The results show that the proposed method is more accurate than other decision-making algorithms, such as decision trees, Naïve Bayes, and ANN. From the perspective of healthcare professionals, the proposed medical decision support system is simple, comprehensive, and more effective than previous models for assessing the risk of GC and can…[Read more]

  • In various domains, there are abundant streams or sequences of multi-item data of various kinds, e.g. streams of news and social media texts, sequences of genes and sports events, etc. Comparison is an important and general task in data analysis. For comparing data streams involving multiple items (e.g., words in texts, actors or action types in…[Read more]

  • Metal nanoparticles, especially silver nanoparticles (AgNPs), have drawn increasing attention for antimicrobial applications. Most studies have emphasized on the correlations between the antibacterial potency of AgNPs and the kinetics of metallic to ionic Ag conversion, while other antimicrobial mechanisms have been underestimated. In this work,…[Read more]

  • The problem of neurotoxicity associated with some anticancer drugs is also highlighted. Our review encourages further research to better encode the hidden potential of anticancer drugs with the aim of developing prospective repurposed drugs with no toxicity for neurodegenerative disorders.Spinal cord injury (SCI) is an independent risk factor for…[Read more]

  • For example, exposure to aflatoxin, heavy alcohol drinking, possibly dairy (not including yogurt) intake increase, while intake of coffee, fish, and tea, light-to-moderate alcohol drinking, and several healthy dietary patterns (e.g., Alternative Healthy Eating Index) may decrease liver cancer risk. Future studies with large sample size and…[Read more]

  • half (51.2%) of Medicare beneficiaries achieved the composite quality textbook outcome metric. Social vulnerability was associated with lower attainment of textbook outcome and an increased risk of adverse postoperative surgical outcomes after hepatopancreatic surgery.

    Limited information exists regarding the clinical characteristics,…[Read more]

  • Respiratory symptoms, especially the development of severe acute respiratory distress syndrome, dominate the discussion and initial concerns of the population and health professionals. However, the cardiovascular system is greatly affected by these conditions and is often responsible for complications and mortality of these patients. In order to…[Read more]

  • Acute toxicity studies showed that LD50 was greater than 5000 mg/kg. The study showed that the crude extract of E. hirta at 200 mg/kg when administered alone had 54% inhibition of ulceration while when administered together with honey increased to 94% inhibition of ulceration, but honey alone had 89.47% inhibition of ulceration. This implied tha…[Read more]

  • Squamous cell carcinoma oral tongue (SCCOT) in patients below 45 years is relatively uncommon in literature; however, there have been increasing trends in incidence. Previous studies showed conflicting data, with no conclusive evidence of differences in outcome compared with older patients. The aim of our study was to determine if younger patients…[Read more]

  • The activin-like kinases are a family of kinases that play important roles in a variety of disease states. Of this class of kinases, ALK2, has been shown by a gain-of-function to be the primary driver of the childhood skeletal disease fibrodysplasia ossificans progressiva (FOP) and more recently the pediatric cancer diffuse intrinsic pontine…[Read more]

  • Objective To determine the presence of Rickettsia typhi in Rhipicephalus sanguineus s.l. and Amblyomma mixtum in southern Mexico. Materials and methods Ticks were collected in humans and domestic animals. The presence of Rickettsia was determined by PCR and sequencing. Results 10/39 work vials amplified fragments of the gltA, htrA and ompB genes.…[Read more]

  • 96) or e-Vol DX (0.92) in image analysis. The OP300 device presented a similar performance of the PreXion 3D in teeth with different endodontic fillings. When using e-Vol DX, the accuracy of Kodak 9000 3D improved from 0.62 to 0.74.

    The PreXion 3D device is the most accurate when detecting VRF, with a performance similar to the OP300 in…[Read more]

  • The risk score was an independent prognosis predictor in the breast cancer cohorts. This study evidenced EGRs’ significance for tumor immunity, demonstrating that the EGR family may be a potential immunotherapeutic target for breast cancer. The 14-gene immune signature is a promising prognostic biomarker in breast cancer.Two new computational…[Read more]

  • In this review, we focus on recent progress that highlights the crucial role of alterations in mitochondrial function and oxidative stress in the pathogenesis of AD, emphasizing a framework of existing and potential therapeutic approaches.Background More and more elderly patients are being diagnosed with arteriovenous malformation (AVM) in this…[Read more]

  • Controlling morphology, adopting metal cations and introducing crystal water are three effective strategies to improve the electrochemical performance of various battery electrodes. However, the effects of simultaneously applying these three strategies to aqueous rechargeable zinc batteries (ARZBs) are rarely demonstrated. Herein, hierarchical H11…[Read more]

  • The major problem with transfemoral prostheses is their capacity to compensate for the loss of the knee joint. The identification of gait-cycle phases plays an important role in the control of these prostheses. Such control is completely up to the patient in passive prostheses or partly facilitated by the prosthesis in semiactive prostheses. In…[Read more]

  • We investigated how differential payoffs affect the temporal discrimination of humans. In a temporal bisection task, participants learned to make one response after a short sample and another after a long sample. When presented with a range of intermediate samples, the proportion of responses fitted well a Gaussian-like distribution function…[Read more]

  • of A. membranaceus var. mongholicus.Recent studies investigated the association of cardiorespiratory fitness with white matter microstructure in children, yet little work has explored to what extent other components of physical fitness (i.e., muscular or motor fitness) are associated with white matter microstructure. Indeed, this association has…[Read more]

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