• onsidered in former use of Vitamin K antagonist and antiplatelet or high white blood cells count.

    We suggest that rural patients aged ≥80 may be safely treated with IVT in routine practice. However, lower efficacy and a higher mortality must be considered in former use of Vitamin K antagonist and antiplatelet or high white blood cells c…[Read more]

  • 0433) and biological agents (p less then 0.0494). There was no difference in retrospective perception of pain, anxiety and social activity limitations between CD and UC patients at diagnosis and the worst flare. The level of limitations in social activity correlated with hospitalisations due to relapse, days spent in the hospital, number of…[Read more]

  • Haas Dogan posted an update 8 months, 1 week ago

    PURPOSE The clinical importance of tissue CEA levels for predicting tumor response to preoperative chemoradiotherapy (CRT) for rectal cancer has not been studied. METHODS Serum CEA levels and tissue CEA expressions for 117 patients who underwent preoperative CRT for rectal cancer, were prospectively collected and analyzed at a tertiary university…[Read more]

  • Two new species of the genus Scaphidium Olivier from Xizang (Tibet Autonomous Region), China are described 1) S. rhopaliparamerosum sp. nov. , distinguished by four dark red big fasciae on apical 1/3 and basal 1/3 parts of elytra; and 2) S. russipenne sp. nov. , distinguished by the unified brownish red colour on elytra. For both new species, we…[Read more]

  • Liver dysfunction is highlighted by several studies as a relevant complication in the context of coronavirus disease 2019 (COVID-19). We present a pediatric patient with mild phenotype but transient severe liver injury. Hepatic damage should be considered even in mild cases of the disease to ensure prompt recognition and management.

    Overall,…[Read more]

  • 6 ± 8.6 days vs. 10.8 ± 7.9 days; P=0.008). IEAT was an independent risk factor for longer LOS along with aCCI score ≥2, lung disease and cardiac disease.

    Empirical use of fluoroquinolones for UTIs should be avoided, especially in male patients with aCCI score >6. Improved empirical antimicrobial therapy may have a beneficial impact in red…[Read more]

  • This study revealed that dam construction was an important and indirect driver for the SOC turnover, and the subsequent effects on the upland soil ecosystem must be considered when large-scale disturbance activities (such as dam construction) are conducted in the future.Retinal diseases, such as age-related macular degeneration and diabetic…[Read more]

  • High-elevation montane forests are disproportionately important to carbon sequestration in semiarid climates where low elevations are dry and characterized by low carbon density ecosystems. However, these ecosystems are increasingly threatened by climate change with seasonal implications for photosynthesis and forest growth. As a result, we…[Read more]

  • The current pandemic caused by SARS-CoV-2 virus is going to be a prolonged melee. Identifying crucial areas, proactive planning, coordinated strategies and their timely implication is essential for smooth functioning of any system during a crunch. Addressing the impact of COVID-19 on transfusion services, there are 4 potential challenges viz.…[Read more]

  • aureus infections and to increase the antibacterial activity of antibiotics commonly used against S. aureus.Complex three-dimensional (3D) cell cultures are being increasingly implemented in biomedical research as they provide important insights into complex cancer biology, and cell-cell and cell-matrix interactions in the tumor microenvironment.…[Read more]

  • 22% of the patients had coronary artery disease (CAD). Additionally, 44.4% representing 12 patients with ST-segment elevation acute myocardial infarction (STEMI), four patients 14.8% presented with a non-ST-segment elevation myocardial infarction (NSTEMI), and nine patients 33.33% offered with unstable angina. Besides, 13 patients were diagnosed…[Read more]

  • Rush Leth posted an update 8 months, 1 week ago

    To investigate alveolar bone loss (ABL), which is an indicator of periodontitis, and to identify risk factors for ABL in an older population between 2008 and 2018.

    This longitudinal study used data from a questionnaire survey and a clinical examination administered on two occasions ten years apart to 273 individuals who were 65years and…[Read more]

  • In conclusion, this study provided the first evidence for the involvement of the hypothalamus in the promotion effect of SNS on OTM. This work could provide a novel theoretical and experimental basis for further understanding of the molecular mechanism of OTM.

    This study aimed to predict the presence and mechanism of busulfan drug-drug…[Read more]

  • PCSK9 is secreted into the circulation, mainly by the liver, and interacts with low-density lipoprotein receptor (LDLR) homologous and non-homologous receptors, including CD36, thus favouring their intracellular degradation. As PCSK9 deficiency increases the expression of lipids and lipoprotein receptors, thus contributing to cellular lipid…[Read more]

  • When bacterial cells come in contact, antagonism mediated by the delivery of toxins frequently ensues. The potential for such encounters to have long-term beneficial consequences in recipient cells has not been investigated. Here, we examined the effects of intoxication by DddA, a cytosine deaminase delivered via the type VI secretion system…[Read more]

  • an informatics curriculum; the provision of resident practice habits data by nearly all residency programs despite lack of clarity surrounding this Accreditation Council for Graduate Medical Education requirement; continued use of case-taking in the post-oral boards era; frequent disclosure of the Match rank list to departmental and hospital…[Read more]

  • For those patients with valvular heart disease, cardiomyopathy, or hypertension, it is reasonable to initiate a progestin-only method until clarification of the safety of an estrogen-containing method is determined in conjunction with the patient’s cardiologist. Contraceptive counseling should be patient-centered, free of coercion, and should…[Read more]

  • We also found that rs2735971-rs2839698-rs3024270 A-C-C may have a significantly lower risk of CAD. The recessive genetic model of rs3024270 could predict the severity of CAD.Background Acute pancreatitis (AP) is a life-threatening disease caused by a variety of factors, and once it progresses to severe acute pancreatitis, the prognosis is poor.…[Read more]

  • Haas Dogan posted an update 8 months, 1 week ago

    PURPOSE The clinical importance of tissue CEA levels for predicting tumor response to preoperative chemoradiotherapy (CRT) for rectal cancer has not been studied. METHODS Serum CEA levels and tissue CEA expressions for 117 patients who underwent preoperative CRT for rectal cancer, were prospectively collected and analyzed at a tertiary university…[Read more]

  • In this study, a photocatalytic reactor with a novel engineering design has been used for the extended degradation of sulfamethazine (SMZ). The reactor employed four consecutive stainless-steel plates immobilized by tungsten-dope TiO2 (W-TiO2) using polysiloxane. The characterization of W-TiO2 by X-ray diffraction (XRD), Raman spectroscopy, and…[Read more]

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