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Rahbek Kearney posted an update 8 months, 1 week ago
Social ties are the most important resource human beings have. Although other people can be difficult and challenging, they can also provide protection, solace, and social support, among other benefits. However, some relationships can be toxic and because these adverse conditions can be physiologically taxing, they can negatively affect both…[Read more]
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Porter Fry posted an update 8 months, 1 week ago
Furthermore, DS-5272 significantly decreased vascular endothelial growth factor concentrations in both sera and ascites. Combined therapy with MDM2 inhibitors and everolimus showed synergistic, and dose-reduction potential, for clear cell carcinoma treatment. Our findings suggest that MDM2 inhibitors represent promising molecular targeted therapy…[Read more]
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Karlsson Andrews posted an update 8 months, 1 week ago
Circadian clock is important to maintain the physiological functions, as maintenance of immune system. A strategy for imposes rhythmicity in the physiological systems may be adopted of exercise training routine. The lifelong regular practice of physical exercise decelerates the processes of aging, providing better quality and prolongation of life.…[Read more]
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Weinreich Vasquez posted an update 8 months, 1 week ago
lity as a central component is warranted.
PROSPERO registration CRD42021236541.
PROSPERO registration CRD42021236541.
Both mutant ert-c.1 and ert-d.7 carry T2-T3 translocations in the Ert-c gene. Principal coordinate analyses revealed the translocation types and translocation breakpoints. Mutant ert-d.7 is an Ert-c Ert-d double…[Read more]
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Mays Silver posted an update 8 months, 1 week ago
This review focuses on the available data regarding the utility of advanced left ventricular (LV) imaging in aortic stenosis (AS) and its potential impact for optimising the timing of aortic valve replacement. Ejection fraction is currently the only LV parameter recommended to guide intervention in AS. The cut-off value of 50%, recommended for…[Read more]
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Petterson Miranda posted an update 8 months, 1 week ago
0001) 6 specific risk scores (10 models) for SSIs after CABG. Although ASSIST performed differently in the 2 validation samples, in both, as well as in the derivation data set, the combined model outweighed (albeit not always significantly) the preoperative-only model, both for additive and logistic ASSIST.
In the derivation data set,…[Read more]
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McHugh Mouridsen posted an update 8 months, 1 week ago
The aim of this study is to compare the clinical outcomes of posteroanterior (PA) lag screws versus posterior buttress plate fixation in treatment of posterior malleolar fragments (PMFs) in spiral tibial shaft fracture, and provide guidance for surgeons selecting a treatment strategy. A total of 48 eligible patients with PMFs associated with…[Read more]
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Whitehead Pape posted an update 8 months, 1 week ago
The mean distance of eye movement was significantly shorter in the DRI group than in the WLI group for all endoscopists. Conclusions DRI can offer useful images that can help in clearly detecting bleeding points and in facilitating hemostasis during ESD. It is feasible and may help in successfully performing ESD that is safer and faster than…[Read more]
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Holst Cain posted an update 8 months, 1 week ago
Interestingly, our results suggested distinct mechanisms of tolerance to salinity between the two species considered, with S. brachiata likely having a more efficient mechanism of response to NaCl.Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Resatorvid…[Read more]
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Hartvig Daniels posted an update 8 months, 1 week ago
Spring-assisted surgery for the correction of scaphocephaly has gained popularity over the past 2 decades. Our unit utilizes standardized torsional springs with a central helix for spring-assisted surgery. This design allows a high degree of accuracy and reproducibility of the force vectors and force distance curves. In this manuscript, we expand…[Read more]
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Franks Bryan posted an update 8 months, 1 week ago
9400 +/- 0.0041. To better assess the effectiveness of MISSIM, we compared it with various classifiers and former prediction models. Its performance is superior to the previous method. These results provide ample convincing evidence of this approach have potential value and prospect in promoting biomedical research productivity.Unsupervised domain…[Read more]
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Post Tanner posted an update 8 months, 1 week ago
1, 95% confidence interval (CI) 1.4-3.1). BCC incidence was not associated with these therapies. Skin lesions in OTRs that are treated with cryotherapy, diathermy, or topical treatment warrant judicious selection and careful follow-up.
Aromatase inhibitor (AI)-associated bone loss increases the risk of bone fracture and reduces patients’…[Read more]
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Morales Tanner posted an update 8 months, 1 week ago
001% by using purified plasmid DNAs and blood cell DNAs containing known proportions of FLT3D835Y. We analyzed blood cell DNA samples from 64 patients with AML and found six FLT3D835Y-positive cases, two of which could not be detected by conventional DNA sequencing methods. Importantly, the method was able to detect FLT3D835Y in a sample collected…[Read more]
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Greene Regan posted an update 8 months, 1 week ago
There was a significant correlation between inflow jet patterns evaluated by CFD and 4D flow MRI (p=0.008). Moreover, there was a strong correlation between the inflow rate ratios evaluated by CFD and 4D flow MRI (r=0.801; p <0.001). Furthermore, there was a moderate correlation between the velocity ratios measured by CFD and 4D flow MRI (r=0.559;…[Read more]
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Gravesen Frank posted an update 8 months, 1 week ago
T follicular helper (Tfh) cells are crucial for the establishment of germinal centers (GCs) and potent antibody responses. Nevertheless, the T cell-intrinsic factors that are required for the maintenance of already-established Tfh cells and GCs remain largely unknown. Here, we use temporally guided gene ablation in CD4+ T cells to dissect the…[Read more]
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Wu McKenna posted an update 8 months, 1 week ago
Serum lipids have been shown to regulate inflammatory and immune processes, but little is known about their association with thyroid autoimmunity. This study aimed to investigate the association of serum lipids with thyroid autoantibody positivity in the general population with normal thyroid-stimulating hormone (TSH) levels.
Data…[Read more]
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Have Fuentes posted an update 8 months, 1 week ago
Increased concentrations of lactate levels in blood are often seen in patients with life-threatening cellular hypoperfusion or infections. State-of-the-art techniques used in clinical practice for measuring serum lactate concentrations rely on intermittent blood sampling and do not permit continuous monitoring of this all important parameter in…[Read more]
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Paaske Dotson posted an update 8 months, 1 week ago
Sufficient sleep during childhood is important for cognitive functions such as learning and successful school performance. This study aimed to investigate the effects of sleep duration on the intelligence quotient (IQ) of 6-year-old children and aimed to analyze whether these effects differed by sex.
The IQ of 538 6-year-old Korean…[Read more]
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Kearney Deal posted an update 8 months, 1 week ago
Our aim was to evaluate the safety and efficacy of low-dose mineralocorticoid receptor antagonists (MRAs) in dialysis patients.
We systematically searched PubMed, EMBASE, and Cochrane libraries for clinical trials on the use of MRAs in dialysis patients. Review Manager 5.3 software was used to analyze relevant data and evaluate the quality…[Read more]
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Mohammad Frandsen posted an update 8 months, 1 week ago
With the growing incidence of new cases and the increasing prevalence of patients living longer with spine metastasis, a methodological approach to the management of patients with recurrent or progressive disease is increasing in relevance and importance in clinical practice. As a result, disease management has evolved in these patients using…[Read more]
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