• age, employment, resilience and coping styles. Future responses to such public health threats may wish to provide sex- and/or age-appropriate supports for psychological health and emotional well-being to those at greatest risk of experiencing stress.

    The self-reported stress of Chinese residents related to the COVID-19 pandemic was…[Read more]

  • We present a series of six critically ill children with Multisystem Inflammatory Syndrome in Children (MIS-C). Key findings of this syndrome include fever, diarrhea, shock, and variable presence of rash, conjunctivitis, extremity edema, and mucous membrane changes.Background It is critical to obtain informed consent from eligible patients to…[Read more]

  • Targeting epidermal growth factor receptor (EGFR) through tyrosine kinase inhibitors (TKI) is a successful therapeutic strategy in non-small cell lung cancer. However, the response to TKI therapy depends on specific activating and acquired mutations in the tyrosine kinase domain of the EGFR gene. Therefore, confirming the EGFR status of patients…[Read more]

  • Hart Kirby posted an update 8 months, 1 week ago

    1%) met national testing guidelines. The number of tests ordered by genetic health professionals reduced significantly (z = 45.0, p = 0.008). Oncology healthcare professionals’ perceived barriers to mainstreamed testing decreased from baseline to follow-up (t = 2.39, p = 0.023), particularly perceived skills, knowledge and attitudes. However, only…[Read more]

  • Lupus nephritis is an important cause of both acute kidney injury and chronic kidney disease that can result in end-stage renal disease. Its pathogenic mechanisms are characterized by aberrant activation of both innate and adaptive immune responses, dysregulation of inflammatory signaling pathways, and increased cytokine production. Treatment of…[Read more]

  • 5% from a median of 334 mm2 (IQR = 294.9-349.8) to 228.8 mm2. The most important clinical considerations are the reproducibility and reliability of the anatomical points, as well as the associated morphological changes. We propose using the vomer edge to establish a validated measuring method for the width, area, and height of the true cleft.The…[Read more]

  • The coating with Triclosan-loaded nanogels shows a killing efficacy of up to 99.99% of adhering bacteria on the surface compared to nonquaternized nanogel coatings while still possessing an antifouling activity. This powerful multifunctional coating for combating biomaterial-associated infection is envisioned to greatly impact the design…[Read more]

  • There are some clues that bring to mind rare entities. Firstly, these patients generally present with various systemic manifestations. Secondly, if there is any discrepancy between voice quality and endoscopic laryngeal examination, the diagnosis should be reconsidered. Thirdly, in the case of the prolonged dysphonia recalcitrant to treatment, the…[Read more]

  • Background Early detection of community health risk factors such as stress is of great interest to health policymakers, but representative data collection is often expensive and time-consuming. It is important to investigate the use of alternative means of data collection such as crowdsourcing platforms. Methods An online sample of Amazon…[Read more]

  • No effective method has yet been developed to prevent the threat posed by the emerging disease-cercarial dermatitis (swimmer’s itch), caused by infective cercariae of bird schistosomes (Digenea Schistosomatidae). In our previous studies, the New Zealand mud snail-Potamopyrgus antipodarum (Gray, 1853; Gastropoda, Tateidae)-was used as a barrier…[Read more]

  • Parkinson’s Disease (PD) is a common neurodegenerative disease which impacts millions of people around the world. In clinical treatments, freezing of gait (FoG) is used as the typical symptom to assess PD patients’ condition. Currently, the assessment of FoG is usually performed through live observation or video analysis by doctors. Considering…[Read more]

  • Fox Hester posted an update 8 months, 1 week ago

    The degree of proteinuria after kidney transplantation predicts graft and patient survival in this population. Pharmacological and non-pharmacological treatments that attenuate proteinuria have been associated with better prognosis of kidney disease.A basal level of proteinuria is about 30-100 mg/day, the upper limit of basal proteinuria does not…[Read more]

  • Larger peak currents are observed for MOF-399 analog films compared to MOF-14 analog films, which is consistent with the larger pores of MOF-399. The layer-by-layer deposition of these systems provides a promising route to incorporate MOFs as thin films with nanoscale thickness control and low surface roughness for electrochemical devices.The…[Read more]

  • We evaluated longitudinal trends and associations between bone mass, bone turnover and inflammatory markers among South African children living with HIV (CLHIV) and controls.

    We previously reported decreased bone mass among CLHIV independent of marked inflammation and increased bone turnover. The goal of this study was to evaluate…[Read more]

  • The synthesized data indicated that the emergence and spread of AMR of malaria, tuberculosis and HIV have resulted in adverse public health, clinical and economic outcomes. AMR of malaria, tuberculosis and HIV results in significant adverse impacts on public health, clinical and economic outcomes. Evidence from this review suggests the needs to…[Read more]

  • Of these patients, 32.8% reported a positive family history of kidney disease. This study confirms that a significant proportion of patients on renal replacement therapy do not have an etiological diagnosis and may be subject to a genomic evaluation. With the increasing availability of genomic sequencing technology and the falling of related…[Read more]

  • 05). Complement 8 beta chain (C8B) expression levels had protective effects on overall survival (OS) and recurrence-free survival (RFS) in HBV-related HCC patients. High levels of C8B contributed to favorable OS and RFS in this population (both p < 0.01), even after adjustment of clinicopathological characteristics including tumor node metastasis…[Read more]

  • The regression analysis indicated a higher risk of distress with increasing age and greater negative religious coping.

    In this sample, higher means were found in the dimension of positive distress experiences; negative coping, although utilized less, had greater potential to exacerbate distress after adjustment for age, in contrast to that…[Read more]

  • Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in the perinatal period. learn more This condition results from a period of ischemia and hypoxia to the brain of neonates, leading to several disorders that profoundly affect the daily life of patients and their families. Currently, therapeutic…[Read more]

  • The prevalence and incidence of diabetes mellitus (DM) are increasing worldwide. We aim to assess mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US and evaluate their recent trends. We examined in-hospital mortality, length of stay (LoS), and overall hospital charges in diabetic patients over 18…[Read more]

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