• Bulgaria is one of European countries where trichinellosis continues to be regularly diagnosed and registered. The clinical and epidemiological features of 72 cases of trichinellosis associated with five outbreaks caused by Trichinella spiralis and Trichinella britovi between 2009 and 2011, are described. At hospital admission, patients were often…[Read more]

  • Surface PM2.5 concentrations are required for exposure assessment studies. Remotely sensed Aerosol Optical Depth (AOD) has been used to derive PM2.5 where ground data is unavailable. However, two key challenges in estimating surface PM2.5 from AOD using statistical models are (i) Satellite data gaps, and (ii) spatio-temporal variability in…[Read more]

  • Introduction Recent evidence has implicated the precuneus of the medial parietal lobe as one of the first brain areas to show pathological changes in Alzheimer’s disease (AD). Damage to the precuneus through focal brain injury is associated with impaired visually guided reaching, particularly for objects in peripheral vision. This raises the…[Read more]

  • Practitioners of traditional medicine use the decoction of Ononis natrix L. to treat hyperglycemia. The literature offers no evidence to support the use.

    To investigate the effect of the decoction of Ononis natrix L. on the blood glucose concentration in Wistar rats (Rattus norvegicus) with streptozotocin-induced diabetes mellitus.…[Read more]

  • 2 and 35.6 mg/kg, respectively. Zn application also increased the 1,000-kernel weight of inferior grain due to high biomass accumulation. Furthermore, the grain Zn concentration of inferior grain with Zn application increased by 24.3-74.9% compared with no Zn application. Thus, soil application of Zn fertilizer successfully increased grain yield…[Read more]

  • pping of complex traits in sheep.

    Our findings provide novel insights into the biological and genetic mechanisms underlying wool and growth traits, and thus will contribute to the genetic improvement and gene mapping of complex traits in sheep.Purpose The objective of this study was to examine the incidence of false-negative screening results…[Read more]

  • LR was an independent risk factor for predicting RFS in T1-2N0M0 lung adenocarcinoma patients after curative surgical resection. BLR can be used as a biomarker for evaluating the risk of lung cancer recurrence.

    BLR was an independent risk factor for predicting RFS in T1-2N0M0 lung adenocarcinoma patients after curative surgical resection. BLR…[Read more]

  • A questionnaire was disseminated to each participating physician to evaluate barriers to access to genetic sequencing and changes in disease management and treatment after testing. One hundred fifty-eight patients and 29 family members were tested in this pilot study. Twenty-one percent of patients with a suspected monogenic disorder received a…[Read more]

  • Thyroid cancer with distant metastasis (TCDM) at diagnosis has significantly worse survival rates when compared to localized/regional thyroid cancer. https://www.selleckchem.com/products/5-chloro-2-deoxyuridine.html This study sought to report on the characteristics of patients presenting with TCDM and the potential survival advantage of surgical…[Read more]

  • Repetitive and sensory behaviors positively impacted the probability of unique maternal endorsement, but this effect was countered by shifts in emotional state and bodily movements. Hand activity was not meaningfully associated with unique maternal endorsement.

    Mothers’ and clinical researchers’ divergence in interpreting communication may be…[Read more]

  • Krogh Wu posted an update 8 months, 2 weeks ago

    ificant in predicting all the DASS-21 scales.

    About a third of respondents reported moderate to extremely severe depression, anxiety, and stress. The present study suggests that psychological resilience may independently contribute to low emotional distress and psychological ill-being. These findings can help explain the variability of…[Read more]

  • To assess intervention impact by group, we used an intention-to-treat analysis, comparing men in each masculinity class, by intervention and control arm, using generalized estimating equations reporting unadjusted and adjusted odds ratios (aORs). In total 674 were recruited at baseline, and the LCA identified three classes of men high violence…[Read more]

  • This selection bias would lead to a systematic underestimation of the cost reduction produced by preventive interventions.

    Prevention course participants seem to have characteristics that differ from the average population (higher health orientation level, preference for prevention over medical treatment services, etc.) and cannot be…[Read more]

  • Predisposing factors for the development of a pre-capillary component in pulmonary hypertension associated with left heart disease remain elusive. We report the case of a patient with persistent combined post-capillary and pre-capillary pulmonary hypertension after cardiac transplantation, in whom a rare BMPR2 variant was found.Pulmonary arterial…[Read more]

  • PorphyStruct, a new digital tool for the analysis of non-planar distortion modes of different porphyrinoids, and its application to corrole structures is reported. The program makes use of the normal-coordinate structure decomposition technique (NSD) and employs sets of normal modes equivalent to those established for porphyrins in order to…[Read more]

  • 42, 95% confidence interval 1.14-1.77; p = 0.003). During a subgroup analysis, COPD was exposed as an independent risk factor of the composite endpoint in nonelderly patients; however, there was not such a finding observed among elderly patients. Separately, there was a significant association with COPD and the composite endpoint in patients wit…[Read more]

  • A miR-125a-5p inhibitor restored BCYRN1 siRNA function in glioma. Conclusion The present study indicates that BCYRN1 promotes glioma cell proliferation, invasion and migration in vitro. Mechanistically, upregulated expression of BCYRN1 in glioma acts as a sponge to sequester the endogenous tumor suppressor miR-125a-5p and to further increase the…[Read more]

  • INTRODUCTION Cardiovascular disease (CVD) is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk.  The aim of this study was to estimate the heritability of circulating lipid species and their genetic correlation with CVD traits.  Methods Targeted lipidomic profiling was…[Read more]

  • Then, mouse embryonic stem cells (mESCs) were transplanted into the scala tympani and survival and distribution of transplanted cells were compared between the acute and chronic auditory neural hearing loss models induced by ouabain or kanamycin (KM), respectively. The mESC survival was similar to the acute model, and perilymphatic distribution of…[Read more]

  • Employing a random assignment strategy, participants were divided into two groups; the first received platelet-rich plasma (PRP), and the second received corticosteroids. The same masked orthopedic surgeon, after locating the pathological site through ultrasound, performed the procedure. To ensure objectivity, VAS scores, DASH scores, PRTEE…[Read more]

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