• Peritoneal cysts are not uncommon in children – mesenteric/omental cysts being the commoner entity. Peritoneal cysts in the falciform ligament are a very rare entity reported in the literature. We present a 5-year-old boy who presented with pain upper central abdomen and few episodes of non-bilious vomiting for 1 year. He was stable on…[Read more]

  • Neutralizing antibodies (nAbs) to SARS-CoV-2 hold powerful potentials for clinical interventions against COVID-19 disease. However, their common genetic and biologic features remain elusive. Here we interrogate a total of 165 antibodies from eight COVID-19 patients, and find that potent nAbs from different patients have disproportionally high…[Read more]

  • The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades, researchers have discovered that organelles are dynamic and form physical contacts. In addition, organelle interactions modulate…[Read more]

  • There is an urgent need to strengthen the implementation of the 3Rs principle (Replacement, Reduction and Refinement) in the use of experimental animals in toxinological research and in the assessment of the neutralizing efficacy of snake antivenoms. click here This is a challenging task owing to the inherent complexity of snake venoms. The state…[Read more]

  • MinIP images can be produced as a derivative from vessel wall imaging and implemented as an adjunct to vessel wall imaging without extra acquisition time.

    MinIP images can be produced as a derivative from vessel wall imaging and implemented as an adjunct to vessel wall imaging without extra acquisition time.Neisseria gonorrhoeae is an urgent…[Read more]

  • AIMS An association between antibody deficiency and clozapine use in individuals with schizophrenia has recently been reported. We hypothesised that if clozapine-associated hypogammaglobulinaemia was clinically relevant this would manifest in referral patterns. METHODS Retrospective case note review of patients referred and assessed by Immunology…[Read more]

  • RNA-binding proteins (RBPs) interacting with target RNAs play essential roles in RNA metabolism at the post-transcription level. Perturbations of RBPs can accelerate cancer development and cause dysregulation of the immune cell function and activity leading to evade immune destruction of cancer cells. However, few studies have systematically…[Read more]

  • To evaluate the safety and efficacy of reduced fluence CXL (lower dose of UV-A irradiation) in mild to moderate keratoconus.

    Farabi Eye Hospital, Tehran, Iran.

    Non-randomized prospective comparative interventional case series. Every eligible patient included in the study (mild to moderate progressive keratoconus) was randomly…[Read more]

  • Duke Holt posted an update 8 months, 2 weeks ago

    These activities may negatively impact river ecosystems and consequently human health.Water use efficiency (WUE) is an environmental factor to account for the metabolism of terrestrial ecosystems using various climate systems and vegetation types. It is estimated by the ratio of gross primary productivity (GPP) to evapotranspiration (ET), the…[Read more]

  • Constitutionnel and Rheological Attributes of Nonedible Plant Oil-Based Plastic resin.

    9 ± 1.0 versus 3.6 ± 1.3 for general treatment satisfaction; 4.3 ± 1.0 versus 3.6 ± 1.0 for self-efficacy, 3.1 ± 0.9 versus 3.9 ± 1.1 for strained social network, 2.1 ± 0.8 versus 3.0 ± 1.0 for daily hassles and 1.8 ± 0.9 versus 2.6 ± 1.2 for distress…[Read more]

  • Genes encoding pathogen pattern-recognition proteins (LGBP, PL5-2 and c-type lectin), prophenoloxidase system (PPAE2, PPAF2 and serpin), antimicrobial peptides (crustin and antiviral protein), blood clotting system (hemolymph clottable protein) and heat shock protein (HSP70) were expressed as they developed further, suggesting that these immune…[Read more]

  • Mechanical thrombectomy is a highly effective but time dependent treatment for acute ischaemic stroke due to large vessel occlusion. In the UK, the national clinical guidelines for stroke and National Institute for Health and Care Excellence guidance endorses thrombectomy as an acute stroke treatment, and NHS England commissioned thrombectomy…[Read more]

  • The importance of centralizing treatment services for severely ill children has been well established, but such entralization remains difficult in Japan. We aimed to compare the trauma and illness severity and mortality of children admitted to two common types of ICUs for children. According to the type of management and disposition of the medical…[Read more]

  • 84 daysversus 3 ± 3.51 days for LM PIVs (p < 0.050, log-rank test).

    Successful implementation of a standardized curriculum for USGPIV placement for PICU nurses improves first stick, overall success, and longevity of PIV catheter placement.

    An ultrasound-guided IV curriculum can be successfully implemented resulting in increase…[Read more]

  • The development may impact clinical practice by providing a resource-saving and objective technology for diagnosing perineal descent in the many patients suffering from anorectal disorders. The technology may also be used in colon experiments with Fecobionics and for other gastrointestinal devices containing IMUs such as ingestible capsules like…[Read more]

  • Data sources Pubmed and EMBASE databases were searched from 2000 to 2017 and complemented by manual searching of the references of reviews and the full-text articles assessed for inclusion.Study selection The inclusion criteria were (i) Randomised clinical trials (RCT), prospective or retrospective studies, and case series or case reports…[Read more]

  • ate a greater rate of rise in thermal sensitivity when exercising in a hot environment, compared to males. Males appeared to adopt a higher risk strategy by increasing power output following l-menthol administration in contrast to a more conservative pacing strategy in females. Therefore, there appear to be sex-specific differences in l-menthol’s…[Read more]

  • Mejia Ali posted an update 8 months, 2 weeks ago

    In conclusion, fusion gene KDM3B-ETF1 inhibits LMO2, activates the Wnt/β-catenin signaling pathway that leads to increased breast cancer cell invasion and metastasis, providing a novel insight into developing therapeutic strategies. Enitociclib order These results provide novel insights into the molecular mechanism of invasive ductal carcinomas,…[Read more]

  • In application, manufacturers and distributers should focus on communicating system information effectively to retain users who may be “forced” to use unfamiliar technologies during the COVID-19 pandemic.

    Theories of human-automation trust inform trajectories of trust development toward unfamiliar technologies for naïve users. In application,…[Read more]

  • uence factors on the acceptance rate/willingness to write of E/C from invitations. 2019 Annals of Translational Medicine. All rights reserved.Background Intracranial atherosclerotic stenosis (ICAS) is the most common cause of stroke, but the relationship of ICAS with fasting blood glucose (FBG) and glycated hemoglobin A1c (HbA1c) is unclear. This…[Read more]

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