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Chavez Bowers posted an update 8 months, 2 weeks ago
Results Under normal glucose concentration, this co-culture with RAW264. 7 promoted C2C12 myotube formation, E-MHC protein expression (P<0. 01), MyoD and myogenin gene expressions (P< 0. 05), insulin-stimulated 2-NBDG uptake (P<0. 05), and basic GLUT4 level (P<0. 05). High glucose stimulation inhibited myotube formation, myogenic regulat…[Read more]
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Shannon Dorsey posted an update 8 months, 2 weeks ago
e., the liver in the case of DTX-TPGS-Gal as compared with non-targeted one. It is concluded from the findings that TPGS-Gal micelles can be utilized for targeted drug delivery of cytotoxic drugs towards HCC with minimized side effects. Graphical abstract.The landscape of cancer treatment has improved over the past decades, aiming to reduce…[Read more]
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Hoppe Payne posted an update 8 months, 2 weeks ago
Although experimental studies directly comparing AD and IS questions yield some mixed results, more studies find IS questions are associated with desirable data quality outcomes (e.g., validity and reliability) and AD questions are associated with undesirable outcomes (e.g., acquiescence, response effects, etc.). Based on available research,…[Read more]
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Lundgren Bendix posted an update 8 months, 2 weeks ago
fective in all scenarios and cost saving in most. It is likely this stratified care model will help reduce unnecessary healthcare usage while improving the patient’s quality of life. Although decision-analytic modelling is used in many conditions, its use has been underexplored in LBP, and this study also addresses associated methodological…[Read more]
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Aycock Lynge posted an update 8 months, 2 weeks ago
Patients with episodic vestibular syndrome (EVS) whose symptoms resemble those of vestibular migraine (VM) but who do not meet the criteria for it are common.
To describe those patients suffering from EVS in whom defined etiologies have been ruled out in order to determine if their symptoms can be linked to VM.
Prospective…[Read more]
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Palmer Reeves posted an update 8 months, 2 weeks ago
The inability to maintain a strictly regulated endo(lyso)somal acidic pH through the proton-pumping action of the vacuolar-ATPases (v-ATPases) has been associated with various human diseases including heritable connective tissue disorders. Autosomal recessive (AR) cutis laxa (CL) type 2C syndrome is associated with genetic defects in the ATP6V1E1…[Read more]
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Lindberg Morrison posted an update 8 months, 2 weeks ago
Those unable to walk 2 km had lower active aging scores irrespective of resilience level. Psychological resilience may alleviate the negative effects of early phase walking difficulties on active aging but may be insufficient to compensate for more severe walking limitations that restrict not only function but also autonomy.Long-term…[Read more]
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Clemensen Bass posted an update 8 months, 2 weeks ago
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Crenigacestat Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).We developed prognostic models for breast cancer-specific survival (BCSS) that…[Read more]
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Slaughter Schwartz posted an update 8 months, 2 weeks ago
ethoxazole-trimethoprim.
The apparent prevalence of AMR in bacteria isolated from sheep is highly dependent on interpretation criteria. The sheep industry may want to establish bespoke cut-off values for AMR monitoring to avoid the use of cut-offs developed for other host species. The latter could lead to high apparent prevalence of…[Read more]
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Crouch Borup posted an update 8 months, 2 weeks ago
e experienced by older adults versus environmental exposures in the Persian Gulf and Afghanistan), providers treating veterans of different ages should be sensitive to era-related effects. Findings suggest the importance of querying for symptoms of mental distress and actively engaging affected individuals, veteran or nonveteran, in appropriate…[Read more]
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Sampson Andresen posted an update 8 months, 2 weeks ago
Several tables are presented that give an overview on the wealth of methods and materials. A concluding section summarizes the current status, addresses current challenges, and gives an outlook on potential future trends. Graphical abstract In recent years, ZIFs and their composites have been widely used as probes in chemical sensing, and these…[Read more]
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Rosenberg Covington posted an update 8 months, 2 weeks ago
Real-time ultrasound (RTUS)-guided central venipuncture using the short-axis approach is complicated and likely to result in losing sight of the needle tip. Therefore, we focused on the eye gaze in our evaluation of the differences in eye gaze between medical students and experienced participants using an eye tracking system.
Ten medical…[Read more]
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Brown McKee posted an update 8 months, 2 weeks ago
In-depth studies of EV-mediated chemoresistance and EV inhibitors in cancer cells would spur significant improvement in cancer treatments which are currently available.Oncoimmunology represents a biomedical research discipline coined to study the roles of immune system in cancer progression with the aim of discovering novel strategies to arm it…[Read more]
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Glud Thomasen posted an update 8 months, 2 weeks ago
The upregulation of these two enzymes ultimately indicate the occurrence of Preparation for Oxidative Stress in the tropical diapause of C. lacinia.Brain regions within a posterior medial network (PMN) are characterized by sensitivity to episodic tasks, and they also demonstrate strong functional connectivity as part of the default network.…[Read more]
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Cooley England posted an update 8 months, 2 weeks ago
We observed that SDS must be combined with proteinase K, dithiothreitol, or both for irreversible and complete RNase inactivation in serum. This work provides an alternative chemistry for inactivating endogenous RNases for use in simple, low-cost point-of-care NATs for blood-borne pathogens.Objective to estimate the ergonomic postural risk for…[Read more]
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Thrane McKay posted an update 8 months, 2 weeks ago
Epidemiology of dengue fever has substantially changed over the years with respect to prevalent strains, affected geographical locations and severity of disease. Mosquito vectors show variable response in terms of susceptibility to four different serotypes of dengue virus. Although studies have postulated that, the vectors Ae. aegypti and Ae.…[Read more]
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Rodgers Falk posted an update 8 months, 2 weeks ago
A large number of ncRNAs with altered levels were observed in plasma, serum, follicular fluid, granulosa cells or other issues from PCOS patients. Aberrant ncRNAs expression in PCOS may lead to aberrant steroidogenesis, adipocyte dysfunction, altered ovarian cell proliferation and/or apoptosis and have the potential to be used as diagnostic…[Read more]
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Kiilerich Burnett posted an update 8 months, 2 weeks ago
Tumor lysis syndrome (TLS) and neutropenia are significant toxicities in the treatment of chronic lymphocytic leukemia (CLL). Both TLS and neutropenia can lead to potentially life-threatening complications for patients with chronic lymphocytic leukemia undergoing antineoplastic therapy. This article focuses on diligent risk assessment,…[Read more]
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Horowitz Kure posted an update 8 months, 2 weeks ago
This perspective represents a major shift in our thinking away from direct effects of isoprene, for example, by changing membrane properties or quenching ROS, to indirect effects, through changes in gene expression and protein abundances. Recognition of isoprene’s role in the growth-defense tradeoff provides new perspectives on evolution of the…[Read more]
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Shannon Dorsey posted an update 8 months, 2 weeks ago
e., the liver in the case of DTX-TPGS-Gal as compared with non-targeted one. It is concluded from the findings that TPGS-Gal micelles can be utilized for targeted drug delivery of cytotoxic drugs towards HCC with minimized side effects. Graphical abstract.The landscape of cancer treatment has improved over the past decades, aiming to reduce…[Read more]
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