• Children with self-limited focal epilepsies of childhood (SLFE) are known to show impaired memory functions, particularly in the verbal domain. Interictal epileptiform discharges (IED) in these epilepsies are more pronounced in nonrapid eye movement (NREM) sleep. Nonrapid eye movement sleep is crucial for consolidation of newly-encoded memories.…[Read more]

  • The present analysis helps to understand the trends in the financial burden of TB on households over last 15years, thus providing evidence to policymakers for more effective channelling of resources in order to achieve a TB-free India by 2025.

    The present analysis helps to understand the trends in the financial burden of TB on households over…[Read more]

  • 05). This is the first study in South Africa to describe the prevalence of E. moshkovskii. E. dispar was significantly associated with abdominal pains (p = 0.003). Further studies are needed to clarify the role of E. moshkovskii and E. dispar in abdominal pain and diarrhoea. © 2020 The Authors.Foodborne diseases are important everywhere in the…[Read more]

  • Smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and is known to have deleterious effects on bone metabolism. However, the effects on bone collagen matrix during the development of COPD are unclear. The aim of this study was to evaluate the temporal effect of cigarette smoke exposure on bone type…[Read more]

  • This showed a clear difference for PlGF (p = 0.003) at day 1. These findings can inform future studies further investigating the cascade of molecular events following fractures and for the prediction of fracture non-union.Non-alcoholic fatty liver disease (NAFLD) is a chronic disease in which excessive amount of lipids is accumulated as droplets…[Read more]

  • RobotReviewer is a machine learning system for semi-automated assistance in risk of bias assessment. The tools’s performance in randomized controlled trials (RCTs) in the field of nursing remains unknown. We aimed therefore to evaluate the agreement in risk of bias assessment between RobotReviewer and human reviewers.

    Evaluation study…[Read more]

  • Natural plant-derived protein with excellent bioactivities has attracted much attention so a functional protein with molecular weight of 15.2 kDa was extracted from Millettia speciosa Champ. leaf for the first time. Under the pH of 12.0, solid-liquid ratio of 140 (w/v), extraction time of 2.0 h, and extraction temperature of 50 °C, the highes…[Read more]

  • Moreover, aPD/IND@MON-aANN nanomedicine also exhibits distinct superiority over the combination therapy of free drugs to potently attenuate the progression of urethane-induced orthotopic lung cancers. Collectively, aPD/IND@MON-aANN nanoplatforms with boosted delivery efficiency via antibody-activated trans-endothelial pathway and enhanced…[Read more]

  • Double-eyelid surgery remains a popular esthetic surgery in East Asian people. The partial-incision method provides the benefits of full-incision and nonincision techniques. It can create a predictable and durable double-eyelid crease.

    To create a long-lasting double-eyelid crease with a minimal scar, the author has described the modified…[Read more]

  • The American Joint Committee on Cancer 8th edition staging system presents separate classifications for pTNM and post-neoadjuvant ypTNM (ypTNM-8th) to enhance prognostic prediction after neoadjuvant therapy and surgery. We aimed to validate the ypTNM-8th staging system and to compare the prognostication performance of ypTNM-8th with that of…[Read more]

  • Food production substantially depletes the environment in different ways, but little is known about how overall dietary patterns relate to these environmental impacts. The objective of this study was to evaluate the environmental performance of different dietary patterns among U.S. adults using life cycle assessment (LCA). A “typical” dietary…[Read more]

  • Background Allergic rhinitis (AR) is a chronic and frequent condition characterized by an excessive response of the immune system to innocent substances encountered in the nasal mucosa. These reactions are mediated by many factors, including chemokines. Chemokine ligand 3 (CCL3, a macrophage inflammatory protein 1α) is a chemokine implicated in…[Read more]

  • This research study highlights the catalytic usage of hetero atoms doped and undoped biogenic carbon nano dots (BCNDs) in the reduction of Alizarine yellow R (AYR) dye. Hydrothermal route was followed to synthesize the eco-friendly and fluorescent undoped as well as, N, B & S doped BCNDs from Syzygium cumini (S. cumini) fruit extract. Synthesized…[Read more]

  • Cyclodextrin (CD)-based polymers are known to efficiently form molecular inclusion complexes with various organic and inorganic guest compounds. In addition, they also have a great potential as metal complexes because deprotonated hydroxyls can strongly bind metal ions under alkaline conditions. The range of environmental conditions for…[Read more]

  • Those who were high in nonjudging endorsed less emotional eating than those who were average or low in nonjudging. This was significant only at low levels of depression. These findings delineate the moderating role of specific aspects of trait mindfulness in the association between depression and emotional eating and may inform more targeted…[Read more]

  • Starting with the theoretical framework for calculating the acoustic radiation force on a compressible spheroid , the present work develops a model for the corresponding acoustic radiation torque. A general result is obtained that may be applied to an object of arbitrary size, shape, and impedance in an arbitrary incident sound field. Like for the…[Read more]

  • This study found that 10

    M MK-4 significantly promoted the osteogenic differentiation of PDLSCs. Gene and protein expression levels of ALP, Runx2, OCN, and Osterix were all upregulated compared with control. Remarkably, after blocking the Wnt/β-catenin signaling pathway with XAV-939, the effect of MK-4 was apparently reversed.

    These…[Read more]

  • In forebrain, stress increased the gene expressions of Egf-Erbb1 and Nrg1/Nrg2-Erbb4 pathways more clearly in 129Sv, whereas the corresponding proteins were significantly elevated in Bl6. We suggest that not only inhibited activity of the DA system, but also reduced activity of EGF family and NMDA receptor signaling underlies higher susceptibility…[Read more]

  • Hydrogen/deuterium exchange (HDX) is used in protein biophysics to probe folding dynamics, intermolecular interactions, epitope and other mapping . A typical procedure often involves HDX in buffered D2O solution followed by pepsin digestion, and liquid chromatography/electrospray ionization Mass Spectrometry (LC-ESI-MS) analysis. In this work, HDX…[Read more]

  • 021), CRP (p = 0.014), and PT (p less then 0.001) and reduced levels of vitamin D. The multivariate regression analysis showed that PT (p = 0.011) and CRP (p = 0.031) were both predictors of vitamin D levels. Subjects with PT and SSc plus PT had significant lower vitamin D values with respect to SSc and to healthy subjects. In addition, PT seems…[Read more]

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