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Cassidy Abrams posted an update 1 year, 1 month ago
Smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and is known to have deleterious effects on bone metabolism. However, the effects on bone collagen matrix during the development of COPD are unclear. The aim of this study was to evaluate the temporal effect of cigarette smoke exposure on bone type…[Read more]
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Hess Albrechtsen posted an update 1 year, 1 month ago
This showed a clear difference for PlGF (p = 0.003) at day 1. These findings can inform future studies further investigating the cascade of molecular events following fractures and for the prediction of fracture non-union.Non-alcoholic fatty liver disease (NAFLD) is a chronic disease in which excessive amount of lipids is accumulated as droplets…[Read more]
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Harris Nicolajsen posted an update 1 year, 1 month ago
RobotReviewer is a machine learning system for semi-automated assistance in risk of bias assessment. The tools’s performance in randomized controlled trials (RCTs) in the field of nursing remains unknown. We aimed therefore to evaluate the agreement in risk of bias assessment between RobotReviewer and human reviewers.
Evaluation study…[Read more]
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Singleton Ruiz posted an update 1 year, 1 month ago
Natural plant-derived protein with excellent bioactivities has attracted much attention so a functional protein with molecular weight of 15.2 kDa was extracted from Millettia speciosa Champ. leaf for the first time. Under the pH of 12.0, solid-liquid ratio of 140 (w/v), extraction time of 2.0 h, and extraction temperature of 50 °C, the highes…[Read more]
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Lykkegaard Colon posted an update 1 year, 1 month ago
Moreover, aPD/IND@MON-aANN nanomedicine also exhibits distinct superiority over the combination therapy of free drugs to potently attenuate the progression of urethane-induced orthotopic lung cancers. Collectively, aPD/IND@MON-aANN nanoplatforms with boosted delivery efficiency via antibody-activated trans-endothelial pathway and enhanced…[Read more]
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Kondrup Sexton posted an update 1 year, 1 month ago
Double-eyelid surgery remains a popular esthetic surgery in East Asian people. The partial-incision method provides the benefits of full-incision and nonincision techniques. It can create a predictable and durable double-eyelid crease.
To create a long-lasting double-eyelid crease with a minimal scar, the author has described the modified…[Read more]
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Weiss Kold posted an update 1 year, 1 month ago
The American Joint Committee on Cancer 8th edition staging system presents separate classifications for pTNM and post-neoadjuvant ypTNM (ypTNM-8th) to enhance prognostic prediction after neoadjuvant therapy and surgery. We aimed to validate the ypTNM-8th staging system and to compare the prognostication performance of ypTNM-8th with that of…[Read more]
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Curtis Dillon posted an update 1 year, 1 month ago
Food production substantially depletes the environment in different ways, but little is known about how overall dietary patterns relate to these environmental impacts. The objective of this study was to evaluate the environmental performance of different dietary patterns among U.S. adults using life cycle assessment (LCA). A “typical” dietary…[Read more]
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Timmons Abel posted an update 1 year, 1 month ago
Background Allergic rhinitis (AR) is a chronic and frequent condition characterized by an excessive response of the immune system to innocent substances encountered in the nasal mucosa. These reactions are mediated by many factors, including chemokines. Chemokine ligand 3 (CCL3, a macrophage inflammatory protein 1α) is a chemokine implicated in…[Read more]
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Orr Cameron posted an update 1 year, 1 month ago
This research study highlights the catalytic usage of hetero atoms doped and undoped biogenic carbon nano dots (BCNDs) in the reduction of Alizarine yellow R (AYR) dye. Hydrothermal route was followed to synthesize the eco-friendly and fluorescent undoped as well as, N, B & S doped BCNDs from Syzygium cumini (S. cumini) fruit extract. Synthesized…[Read more]
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Abbott Hall posted an update 1 year, 1 month ago
Cyclodextrin (CD)-based polymers are known to efficiently form molecular inclusion complexes with various organic and inorganic guest compounds. In addition, they also have a great potential as metal complexes because deprotonated hydroxyls can strongly bind metal ions under alkaline conditions. The range of environmental conditions for…[Read more]
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Moses Levin posted an update 1 year, 1 month ago
Those who were high in nonjudging endorsed less emotional eating than those who were average or low in nonjudging. This was significant only at low levels of depression. These findings delineate the moderating role of specific aspects of trait mindfulness in the association between depression and emotional eating and may inform more targeted…[Read more]
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Wiese Albert posted an update 1 year, 1 month ago
Starting with the theoretical framework for calculating the acoustic radiation force on a compressible spheroid , the present work develops a model for the corresponding acoustic radiation torque. A general result is obtained that may be applied to an object of arbitrary size, shape, and impedance in an arbitrary incident sound field. Like for the…[Read more]
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Moses Steenberg posted an update 1 year, 1 month ago
This study found that 10
M MK-4 significantly promoted the osteogenic differentiation of PDLSCs. Gene and protein expression levels of ALP, Runx2, OCN, and Osterix were all upregulated compared with control. Remarkably, after blocking the Wnt/β-catenin signaling pathway with XAV-939, the effect of MK-4 was apparently reversed.
These…[Read more]
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Conner Tate posted an update 1 year, 1 month ago
In forebrain, stress increased the gene expressions of Egf-Erbb1 and Nrg1/Nrg2-Erbb4 pathways more clearly in 129Sv, whereas the corresponding proteins were significantly elevated in Bl6. We suggest that not only inhibited activity of the DA system, but also reduced activity of EGF family and NMDA receptor signaling underlies higher susceptibility…[Read more]
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Wynn Stiles posted an update 1 year, 1 month ago
Hydrogen/deuterium exchange (HDX) is used in protein biophysics to probe folding dynamics, intermolecular interactions, epitope and other mapping . A typical procedure often involves HDX in buffered D2O solution followed by pepsin digestion, and liquid chromatography/electrospray ionization Mass Spectrometry (LC-ESI-MS) analysis. In this work, HDX…[Read more]
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Tierney Bladt posted an update 1 year, 1 month ago
021), CRP (p = 0.014), and PT (p less then 0.001) and reduced levels of vitamin D. The multivariate regression analysis showed that PT (p = 0.011) and CRP (p = 0.031) were both predictors of vitamin D levels. Subjects with PT and SSc plus PT had significant lower vitamin D values with respect to SSc and to healthy subjects. In addition, PT seems…[Read more]
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Post Lucas posted an update 1 year, 1 month ago
Consistent with this finding, the mutated CTX-M protein hydrolysed nitrofurantoin in a cell-free assay. Detection of a novel nitrofurantoin resistance gene indicates an emerging clinical problem in the treatment of gram-negative ESBL-positive UTI patients.Chitosan (CS) and its derivatives show antimicrobial properties. This is of interest in…[Read more]
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Nissen Clifford posted an update 1 year, 1 month ago
In multivariable analysis, viral load ≥1000 copies/mL, moderate and severe anemia at baseline increased risk of APOs. Among women initiating ART before and after conception, no difference was observed in the composite APO. Women who received community mentor mother visits alone (aRR 0.74 95% CI 0.71 to 0.76) or text messages alone (aRR 0.79 95% C…[Read more]
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Foster Holman posted an update 1 year, 1 month ago
Protein phosphatases, by counteracting protein kinases, regulate the reversible phosphorylation of many substrates involved in synaptic plasticity, a cellular model for learning and memory. A prominent phosphatase regulating synaptic plasticity and neurologic disorders is the serine/threonine protein phosphatase 1 (PP1). PP1 has three isoforms…[Read more]
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