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Korsgaard Mclean posted an update 7 months, 2 weeks ago
In the subgroup of patients with a high ultrafiltration rate (UFR; mean UFR ≥10 mL/kg/h), there were significantly increased ventricular events and ST-segment changes in Phase 2. In conclusion, ECG changes were associated with the dialysis cycle, significantly in the 12-h after early-week HD sessions. These may be associated with low dialysate o…[Read more]
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Lindberg Todd posted an update 7 months, 2 weeks ago
A limited number of interventions have a positive effect on satisfaction of both the persons with cognitive disorders and the caregiver. It is important to focus on interventions that will benefit both simultaneously. More research is needed with a clear definition of satisfaction and the use of the ICHI guidelines.Among the various innovative…[Read more]
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Dam Rose posted an update 7 months, 2 weeks ago
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute pulmonary embolism, characterized by non-resolving fibro-thrombotic obstructions of large pulmonary arteries. Pulmonary endarterectomy (PEA) is the treatment of choice for the disease, significantly improving survival. Patients with worse hemodynamic profile have…[Read more]
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Reynolds From posted an update 7 months, 2 weeks ago
We identified eleven subthemes in the patient interviews and seven subthemes in the GP interviews. Several unmet needs emerged. First, we identified a need to consider PPS early in the illness trajectory by taking a bio-psycho-social approach. Second, both patients and GPs need better skills to manage uncertainty. Third, hope is important for the…[Read more]
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Beyer Miranda posted an update 7 months, 2 weeks ago
AIMS The objectives of the present study were to investigate the mechanisms of Ninj-1 regulation in TNFα-activated human endothelial cells (HEC), and to test if Amlodipine (AML) ameliorates the inflammatory stress by decreasing Ninj-1 expression. MAIN METHODS TNFα-activated HEC with/without AML (0.1 μM and 1 μM) were used. TNFα-receptor 1 (TNF…[Read more]
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Kirkpatrick Bell posted an update 7 months, 2 weeks ago
In 1944, the Journal of Experimental Medicine published the groundbreaking discovery that DNA is the molecule holding genetic information (1944. J. Exp. Med.https//doi.org/10.1084/jem.79.2.137). This seminal finding was the genesis of molecular biology and the beginning of an incredible journey to understand, read, and manipulate the genetic…[Read more]
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Berthelsen Hammer posted an update 7 months, 2 weeks ago
Further, many more evaluation indices are considered for a fair comparison. An elaborate discussion on selecting appropriate method and evaluation metric as per the kind of data is presented. This study may encourage researchers for further work in this domain.Synchronization of human vital signs, namely the cardiac cycle and respiratory…[Read more]
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Krogsgaard Mogensen posted an update 7 months, 2 weeks ago
BACKGROUND Nearly a fifth of the world’s population suffer from migraine headache, yet risk factors for this disease are poorly characterized. METHODS To further elucidate these factors, we conducted a genetic correlation analysis using cross-trait linkage disequilibrium (LD) score regression between migraine headache and 47 traits from the UK…[Read more]
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Warming Lorentzen posted an update 7 months, 2 weeks ago
Firearm violence may indirectly affect health among pregnant women living in neighborhoods where it is endemic. We used birth, death, emergency department, and hospitalization data from California from 2007-2011 to estimate the association between living in a neighborhood with high firearm violence and preterm delivery, and assessed whether there…[Read more]
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Juul Martin posted an update 7 months, 2 weeks ago
Five-year OS estimates by TTC group were 0.82, 0.81, 0.80, and 0.74, respectively (p<.001). BCSS demonstrated a similar trend (p<.001). Chemotherapy delay was associated with worse OS (HR=1.33, 95%CI 1.25-1.40) and BCSS (HR=1.39, 95%CI 1.27-1.53). In subgroup analysis, delayed chemotherapy was associated with worse OS and BCSS among patients with…[Read more]
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Foreman McFadden posted an update 7 months, 2 weeks ago
Further molecular studies are required to fully understand the role of oral keratinocytes in the initiation of OLP.Background Peripartum depression is a public health problem which has been widely studied. Nonetheless, study findings and clinical guidelines for PPD treatment differ among countries and the condition is still underdiagnosed and…[Read more]
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Aycock Jansen posted an update 7 months, 2 weeks ago
Objective To examine the effect of the “four-steps” treatment on infectious pancreatic necrosis(IPN). Methods The data of 207 patients who were diagnosed with IPN from January 2013 to December 2017 at Department of Pancreaticobiliary Surgery, the First Affiliated Hospital of Harbin Medical University were analyzed retrospectively. Among 207…[Read more]
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Offersen Higgins posted an update 7 months, 2 weeks ago
PURPOSE To introduce an assessment tool (rubric) for evaluating ophthalmology residents’ competency in pterygium surgery. METHODS A panel of experienced international surgeons collaborated and developed the rubric. After describing various stages of the procedure, the Dreyfus scale of skill acquisition was used for scoring each stage. After…[Read more]
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Ballard Persson posted an update 7 months, 2 weeks ago
The purified peptide displays antimicrobial activity against E. coli, as previously shown. Furthermore, we also tested its antimicrobial activity against the Gram-positive bacteria Staphylococcus aureus and found that Bin1b is also capable of inhibiting the growth of this bacterium. In conclusion, we developed a practical methodology for the…[Read more]
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Slot Meier posted an update 7 months, 2 weeks ago
The shell structure and release properties of layer-by-layer assembled particles could be tailored by controlling the interactions between starches.Although research on phytochemicals has been a hot topic due to positive effects on human health, modification of starch with phytochemicals has been limited. In the present work, cassava…[Read more]
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McDonough Kaspersen posted an update 7 months, 2 weeks ago
Résultats Un total de 181 participants ont été recrutés pendant la période d’étude. 114 étaient des hommes. Cent douze participants (61,8%) ont eu stade 5 CKD, dont 97 avaient commencé une hémodialyse de maintenance. La prévalence de la LR était de 44,8% (81/181) (intervalle de confiance à 95% 37,4% à 51,9%). Le manque de fonds est la raison la pl…[Read more]
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Beyer Miranda posted an update 7 months, 2 weeks ago
AIMS The objectives of the present study were to investigate the mechanisms of Ninj-1 regulation in TNFα-activated human endothelial cells (HEC), and to test if Amlodipine (AML) ameliorates the inflammatory stress by decreasing Ninj-1 expression. MAIN METHODS TNFα-activated HEC with/without AML (0.1 μM and 1 μM) were used. TNFα-receptor 1 (TNF…[Read more]
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Upchurch Warren posted an update 7 months, 2 weeks ago
Moreover, the compounds of QFY in 90% ethanol downregulated iNOS in BV-2 cells but showed no activity against COX-2 induction. Among the herbal ingredients of QFY, Angelicae Sinensis Radix and Ginseng Radix et Rhizoma contributed to the selective inhibition of iNOS induction. Furthermore, chemical analysis identified ginsenosides, especially Rg3,…[Read more]
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Geisler Buur posted an update 7 months, 2 weeks ago
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was isolated from the oro/pharyngeal swabs of two Italian COVID-19 patients, physicians in a COVID-19 division hospital, with different courses of the disease. The complete genome sequences show that the two isolates belong to the B1.1 lineage, but contain a nucleotide mutation in the…[Read more]
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Wilder Rasch posted an update 7 months, 2 weeks ago
Parkinson’s disease (PD) is associated with proteostasis disturbances and accumulation of misfolded α-synuclein (α-syn), a cytosolic protein present in high concentrations at pre-synaptic neuronal terminals. It is a primary constituent of intracellular protein aggregates known as Lewy neurites or Lewy bodies. Progression of Lewy pathology caused b…[Read more]
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