• Noel Han posted an update 1 year ago

    The development, fast-tracking, and approval of SARS-CoV-2 nanotechnology-based vaccines has transformed the seemingly daunting challenges for clinically translating nanomedicines into measurable hurdles that can be overcome. Due to the tremendous scientific achievements that have occurred in response to the COVID-19 pandemic, years, perhaps even…[Read more]

  • Elgaard Baird posted an update 1 year ago

    aestivum. PRACTICAL APPLICATIONS The current study indicated that the potent efficacy of imidacloprid against different aphid spp. which were the most insect pest in wheat plants. As well as the application of imidacloprid as seed dressing insecticide, significantly increase carbohydrate, protein, amino acids, and RNA content in T. aestivum…[Read more]

  • Mcgowan Meadows posted an update 1 year ago

    Background Several strategies have been proposed to determine onset of puberty without examination by a trained professional. This study sought to evaluate a novel approach to determine onset of puberty in girls. Methods This study utilized the Cincinnati cohort of the Breast Cancer and the Environment Research Program. Girls were recruited at 6-7…[Read more]

  • Jordan Thygesen posted an update 1 year ago

    OBJECTIVE To systematically review and appraise published data, to determine the prevalence of Mycoplasma genitalium (MG) in men who have sex with men (MSM) tested at each anatomical site, that is, at the urethra, rectum and/or pharynx. DESIGN Systematic review and meta-analysis. DATA SOURCES Ovid Medline, PubMed, Embase were searched for articles…[Read more]

  • Gamble Henderson posted an update 1 year ago

    While religiosity is usually associated with lower death anxiety, holding doubts about one’s faith are associated with higher death anxiety. Using longitudinal data from the Religion, Aging, and Health Study (2001-2004), this study examines within-individual changes in religious doubt and death anxiety. Results from lagged dependent variable…[Read more]

  • Burris Stein posted an update 1 year ago

    Treatment with the clinical ATR kinase inhibitor VX-970 induced apoptosis in MYB-positive ACC cells and growth inhibition in ACC PDXs. To our knowledge, ATR is the first example of an actionable target downstream of MYB that could be further exploited for therapeutic opportunities in ACC patients. Our findings may also have implications for other…[Read more]

  • Bradford Swanson posted an update 1 year ago

    Precursor B-cell lymphoblastic lymphoma (PBLL) is a rare subtype of non-Hodgkin lymphoma originating from B-cell precursors. PBLL, as a solitary mass lesion affecting the central nervous system without leukemic disease at presentation, is quite uncommon. Here we report a rare PBLL case with Philadelphia chromosome positivity. The 44-year-old male…[Read more]

  • Brask Iversen posted an update 1 year ago

    Female patients who had been sexually assaulted and who were evaluated at 13 widely geographically distributed sexual assault nurse examiners’ programs consistently reported that the sexual assault nurse examiners provided high-quality, compassionate care.

    We aimed to assess the long-term outcomes of children in whom the aortic valve could be…[Read more]

  • Rush Spears posted an update 1 year ago

    Pyroptosis is a type of proinflammatory regulated cell death (RCD) in which caspase-1 proteolytically cleaves gasdermin D (GSDMD) to yield a cytotoxic pore-forming protein. Recent studies have suggested that additional cell death pathways may interact with GSDMD under certain circumstances to execute pyroptosis. Microglia/macrophages in the…[Read more]

  • Jefferson Ellis posted an update 1 year ago

    To investigate the evidence and provide clinical recommendations for low intensity exercises(LIE) and blood flow restriction(BFR) without exercise on reducing the effects of exercise induced muscle damage(EIMD).

    PubMed, Embase, Web of science, and PEDro(Physiotherapy Evidence Database) were searched up to December 2019 for studies that…[Read more]

  • Riddle Hartvig posted an update 1 year ago

    To identify health professionals awareness of stroke rehabilitation guidelines, and factors perceived to influence guideline use internationally.

    Online survey study. Open-ended responses were thematically analysed, guided by the Consolidated Framework for Implementation Research.

    Data from 833 respondents from 30 countries were…[Read more]

  • Fox Hester posted an update 1 year ago

    1 MPa), and the elongation is 19.9%, 39.8% lower than that of pure aluminum (33.1%).This study examined the cross-sectional and longitudinal association of sleep timing with weight status in 14- to 19-year-old adolescents in Wuhan, China. A prospective school-based study was conducted in Wuhan, China between 28 May and 29 September 2019. Data on…[Read more]

  • Evans Emborg posted an update 1 year ago

    We do believe that a rapid reduction of all modifiable risk factors, especially obesity with its metabolic complications, should be a pillar of public health policies and interventions, in view of future waves of SARS-CoV-2 infection.Trastuzumab resistance in HER2-positive breast cancer is associated with a poorer prognosis. HSP90 is thought to…[Read more]

  • Ipsen Stampe posted an update 1 year ago

    Cancer is one of the most serious health concerns in 21st century whose prevalence is beyond boundaries and can affect any organ of human beings. The conventional chemotherapeutic treatment strategies lack specificity to tumours and are associated with toxic effects on immune system and other organ systems. In the past decades, there has been a…[Read more]

  • Davidsen Sullivan posted an update 1 year ago

    PERCIST measurements were performed for each paired baseline and post-treatment scan. Receiver operating characteristic analysis for the prediction of pCR was performed using logistic regression that included age and tumor size as covariates. SUV and SUL metrics were significantly different between orientation (P .6). Overlapping 95% confidence…[Read more]

  • Dominguez Vogel posted an update 1 year ago

    A unique lanthanide complex which responds to near-infrared (NIR) stimulation was developed for remote regulation of cellular events. This molecule can be localized specifically on the cell surface. Upon NIR stimulation, strong emission of the complex can successfully modulate the activities of light-gated membrane channels and regulate the ion…[Read more]

  • Womble Lowry posted an update 1 year ago

    Leishmaniasis is a neglected disease caused by Leishmania. Chemotherapy remains the mainstay for leishmaniasis control; however, available drugs fail to provide a parasitological cure, and are associated with high toxicity. Natural products are promising leads for the development of novel chemotherapeutics against leishmaniasis. This work…[Read more]

  • Sauer Leth posted an update 1 year ago

    Sexual and gender minority (SGM) individuals experience minority stress, especially when they lack social support. SGM young adults may turn to social media in search of a supportive community; however, social media use can become problematic when it interferes with functioning. Problematic social media use may be associated with experiences of…[Read more]

  • Aguilar Garner posted an update 1 year ago

    FGF-23 has arisen as an early biomarker of renal dysfunction, but at the onset of chronic kidney disease (CKD) data suggest that FGF-23 may be produced independently of the parathyroid hormone (PTH), 1,25(OH)2 -Vitamin D3 signaling axis. Iron status is inversely correlated to the level of circulating FGF-23, and improvement in iron bioavailability…[Read more]

  • Warming Lorentzen posted an update 1 year ago

    Myalgia, increased levels of creatine kinase, and persistent muscle weakness have been reported in patients with COVID-19.

    To study skeletal muscle and myocardial inflammation in patients with COVID-19 who had died.

    This case-control autopsy series was conducted in a university hospital as a multidisciplinary postmortem…[Read more]

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