• Napier Allred posted an update 6 months, 3 weeks ago

    What is the prevalence and pattern of IVF add-on use in Australia?

    Among women having IVF in the last 3 years, 82% had used one or more IVF add-on, most commonly acupuncture, preimplantation genetic testing for aneuploidy and Chinese herbal medicine.

    IVF add-ons are procedures, techniques or medicines which may be considered nonessential to IVF, but usually used in attempts to improve the probability of conception and live birth. The use of IVF add-ons is believed to be widespread; however, there is little information about the prevalence and patterns of use in different settings.

    An online survey was distributed via social media to women in Australia who had undergone IVF since 2017. Women were excluded if they were gestational surrogates, used a surrogate, or underwent ovarian stimulation for oocyte donation or elective oocyte cryopreservation only. The survey was open from 21 June to 14 July 2020.

    Survey questions included demographics, IVF and medical history, and use of IVF add-ons including dets from Wellcome Trust, during the conduct of the study, and that publishing benefits his career. The remaining authors report no conflict of interest.

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    Before and after images are commonly used on Instagram to advertise aesthetic surgical treatments and are a powerful means of prospective patient engagement. Consistency between before and after images accurately demonstrating the postoperative result on Instagram, however, has not been systematically assessed.

    Our aim was to systematically assess facial cosmetic surgery before and after photography bias on Instagram.

    The authors queried 19 Instagram facial aesthetic surgery-related hashtags on 3 dates in May 2020. The “top” 9 posts associated with each hashtag (291 posts) were analyzed by 3 plastic surgeons using 5-item rubric quantifying photographic discrepancies between preoperative and postoperative images. Duplicate posts and those that did not include before and after images after facial aesthetic surgery procedures were excluded.

    A total of 3,477,178 posts were queried. selleck chemical Photography conditions were observed to favor visual enhancement of the post-operative result in 282/291 analyzed top posts, erative result, is pervasive on Instagram. This pattern was observed across all physician specialties and raises significant concerns. Accounts with a greater number of followers demonstrated significantly greater postoperative photography bias, suggesting photographic misrepresentation is awarded by greater user engagement.As COVID-19 continues to spread, with the United States surpassing 29 million cases, health care workers are beginning to see patients who have been infected with SARS-CoV-2 return seeking treatment for its longer-term physical and mental effects. The term long-haulers is used to identify patients who have not fully recovered from the illness after weeks or months. Although the acute symptoms of COVID-19 have been widely described, the longer-term effects are less well known because of the relatively short history of the pandemic. Symptoms may be due to persistent chronic inflammation (eg, fatigue), sequelae of organ damage (eg, pulmonary fibrosis, chronic kidney disease), and hospitalization and social isolation (eg, muscle wasting, malnutrition). Health care providers are instrumental in developing a comprehensive plan for identifying and managing post-COVID-19 complications. This article addresses the possible etiology of postviral syndromes and describes reported symptoms and suggested management of post-COVID syndrome.A method has been proposed to evaluate the kinetic parameters, viz. activation energy ($E$) and order of kinetics ($b$) from a single or isolated thermoluminescence (TL) glow peak. Along with the area under the entire curve, this method uses a set of three arbitrary data points and calculates the partial area under the curve from each point to the endpoint. In this way, the entire information associated with the curve is used and the method is named as ‘Three-Point Area’ (TPA) method. We have applied it successfully on a number of theoretically simulated TL curves generated in One Trap One Recombination centre (OTOR) model and General-Order Kinetics (GOK) model under quasi-equilibrium approximations with linear heating scheme. The activation energies are found in good agreement with input values for both the models. For OTOR model, temperature average of order of kinetics is estimated to compare with the present result. Systematic analysis is carried out for estimation of errors inherent in the method in the purview of GOK model. A closer look on the results reveals that any set of three points, preferably chosen from the rising side of the curve, can yield activation energy and order of kinetics. The validity of the method to extract $E$ and $b$ from experimental glow curves is exemplified by considering experimental TL data reported in literature. Finally, a complete study starting from the synthesis of a new phosphor $\mathrmK_2SrP_2O_7Pr $ and analysis of the recorded TL data to estimate $E$ and $b$ employing the TPA method has been reported.

    Neoplastic seeding (NS) can occur after tissue biopsy, which is a clinical issue especially in mastectomy with immediate reconstruction. This is because postoperative radiation is not usually given and local recurrence of preserved skin flap may increase. The purpose of this study is to investigate the importance of preoperative evaluation of NS and the validity of biopsy scar excision.

    We retrospectively analysed 174 cases of mastectomy with immediate breast reconstruction. The primary endpoint is the frequency of clinical and pathological NS and the secondary endpoint is the problem of excision of needle biopsy site.

    Three cases (1.7%) had preoperative clinical findings of NS. Pathological examination revealed NS in all three cases. Biopsy scars could be excised in 115 cases among 171 cases without clinical NS. Pathological NS was found in 1 of 66 (1.5%) cases of which pathological examination was performed. Biopsy scars could not be excised in the remaining 56 cases the biopsy scar could not be identified in 41 cases, and there was concern about a decrease in flap blood flow after excision in 15 cases.

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