• Bojesen Christensen posted an update 6 months, 2 weeks ago

    Realizing that the instability of the fully laminated state requires a finite extensibility of the sheet, we introduce a simple model that allows us to construct a bifurcation diagram that governs the delamination process.For monolayers of chemically active particles at a fluid interface, collective dynamics is predicted to arise owing to activity-induced Marangoni flow even if the particles are not self-propelled. Here, we test this prediction by employing a monolayer of spherically symmetric active particles located at an oil-water interface with or without addition of a nonionic surfactant. Due to the spherical symmetry, an individual particle does not self-propel. However, the gradients produced by the photochemical fuel degradation give rise to long-ranged Marangoni flows. For the case in which surfactant is added to the system, we indeed observe the emergence of collective motion, with dynamics dependent on the particle coverage of the monolayer. The experimental observations are discussed within the framework of a simple theoretical mean-field model.Cilia are hair-like membrane protrusions that emanate from the surface of most vertebrate cells and are classified into motile and primary cilia. Motile cilia move fluid flow or propel cells, while also fulfill sensory functions. Primary cilia are immotile and act as a cellular antenna, translating environmental cues into cellular responses. click here Ciliary dysfunction leads to severe diseases, commonly termed ciliopathies. The molecular details underlying ciliopathies and ciliary function are, however, not well understood. Since cilia are small subcellular compartments, imaging-based approaches have been used to study them. However, tools to comprehensively analyze images are lacking. Automatic analysis approaches require commercial software and are limited to 2D analysis and only a few parameters. The widely used manual analysis approaches are time consuming, user-biased, and difficult to compare. Here, we present CiliaQ, a package of open-source, freely available, and easy-to-use ImageJ plugins. CiliaQ allows high-throughput analysis of 2D and 3D, static or time-lapse images from fluorescence microscopy of cilia in cell culture or tissues, and outputs a comprehensive list of parameters for ciliary morphology, length, bending, orientation, and fluorescence intensity, making it broadly applicable. We envision CiliaQ as a resource and platform for reproducible and comprehensive analysis of ciliary function in health and disease.”Dysmobility Syndrome” (DS) is a term that correlates sarcopenia and osteoporosis together with mobility disturbances, obesity, fractures, and falls. The prevalence of DS is of 74% in this study. Further research with bigger sample sizes is needed to describe if prevalence and DS characteristics are similar in other studies.

    “Dysmobility Syndrome” (DS) correlates sarcopenia and osteoporosis together with mobility disturbances, obesity, fractures, and falls, all of which are related to adverse outcomes in the health of the elderly; however, there are no studies of DS in Mexican patients. In this study, we aimed to describe the characteristics of DS in Mexican postmenopausal women from a private practice.

    A case-series study was conducted; women of 60 years and older were invited to participate from August to December of 2019, a total of 50 patients were included. Medical history, physical tests, bone densitometry, and body composition analysis were performed; patients who met 3 or more of the following critstudy is higher than the one that is described in global literature. • DS diagnosis is closely related to the antecedent of non-vertebral fragility fracture.This study evaluates the effects of seasonal conditions and exposure periods on trace element concentrations in samples of the epiphytic moss Pylaisia polyantha when transplanted into urban areas. This assessment was carried out in summer and winter at four sites differing in their level of technogenic trace element load. The contents of 25 trace elements (As, Ba, Br, Ca, Ce, Co, Cr, Cs, Eu, Fe, Hf, La, Lu, Mo, Nd, Rb, Sb, Sc, Sm, Sr, Tb, Th, U, Yb, and Zn) were determined using neutron-activation analysis, and it was shown that seasonal conditions do not affect vital activity in P. polyantha graft moss. For most elements, the greatest increase in trace element concentration in P. polyantha transplant moss was observed within one month. The high sensitivity of this epiphytic moss-transplant to the level of technogenic load has thus been demonstrated, and it may find utility in future research with similar objectives.

    3D printing and distributed manufacturing represent a paradigm shift in the health system that is becoming critical during the COVID-19 pandemic. University hospitals are also taking on the role of manufacturers of custom-made solutions thanks to 3D printing technology.

    We present a monocentric observational case study regarding the distributed manufacturing of three groups of products during the period of the COVID-19 pandemic from 14 March to 10 May 2020 personal protective equipment, ventilatory support, and diagnostic and consumable products. Networking during this period has enabled the delivery of a total of 17,276 units of products manufactured using 3D printing technology. The most manufactured product was the face shields and ear savers, while the one that achieved the greatest clinical impact was the mechanical ventilation adapters and swabs. The products were manufactured by individuals in 57.3% of the cases, and our hospital acted as the main delivery node in a hub with 10 other hospitals. The main advantage of this production model is the fast response to stock needs, being able to adapt almost in real time.

    The role of 3D printing in the hospital environment allows the reconciliation of in-house and distributed manufacturing with traditional production, providing custom-made adaptation of the specifications, as well as maximum efficiency in the working and availability of resources, which is of special importance at critical times for health systems such as the current COVID-19 pandemic.

    The role of 3D printing in the hospital environment allows the reconciliation of in-house and distributed manufacturing with traditional production, providing custom-made adaptation of the specifications, as well as maximum efficiency in the working and availability of resources, which is of special importance at critical times for health systems such as the current COVID-19 pandemic.

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