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Harrell Lundgaard posted an update 6 months, 3 weeks ago
ed intubations and tracheostomies were the norm, and a minority had new neurologic presentations. Patients typically improved with assessment that enabled treatment with individualized compensatory strategies. Services preparing for COVID-19 should target resources for tracheostomy weaning and to enable responsive management of dysphagia and dysphonia with robust referral pathways.
Inpatients with COVID-19 present with significant impairments of voice and swallowing, justifying responsive SLT. Prolonged intubations and tracheostomies were the norm, and a minority had new neurologic presentations. Patients typically improved with assessment that enabled treatment with individualized compensatory strategies. Services preparing for COVID-19 should target resources for tracheostomy weaning and to enable responsive management of dysphagia and dysphonia with robust referral pathways.
To assess the prognostic findings of the carcinomatous transformation of odontogenic keratocyst (OKC).
A systematic review of all cases of carcinomatous transformation of OKC was completed, and a case report was included.
A total of 679 publications were screened, and 37 cases met inclusion criteria. The mean age for patients with malignant transformation of OKC was 45.1years. Pain (67.5%) and swelling (78.3%) were the most common symptoms. The malignant transformation occurred with increased frequency in the posterior mandible and larger lesions that span greater than 2 subunits of the involved jaw. Resection was the definitive treatment in all cases and 14 cases (46%) utilized adjuvant treatment.
Patient outcomes and follow-up was variable in our study such that overall survival was difficult to determine. However, overall survival in malignant transformation of odontogenic cysts of all kinds ranges from 62 to 85% and 30 to 8% for 2 and 5years, respectively.
Patient outcomes and follow-up was variable in our study such that overall survival was difficult to determine. However, overall survival in malignant transformation of odontogenic cysts of all kinds ranges from 62 to 85% and 30 to 8% for 2 and 5 years, respectively.
The progression of medication-related osteonecrosis of the jaw (MRONJ) is influenced by many factors. This study aimed to identify the clinical risk factors associated with severe MRONJ (stage 3).
The data of patients with MRONJ who were hospitalized between July 2013 and December 2019 were retrospectively analyzed. Demographic and clinical factors were the independent variables, and the clinical stage of MRONJ lesions was the dependent variable. Multivariate logistic regression analysis was performed to identify the risk factors for advanced stage disease (MRONJ stage 3).
A total of 79 patients (with 93 MRONJ lesions) were included. In multivariate regression analysis, the risk factors associated with stage 3 MRONJ were age ≤65years (odds ratio =3.968, 95% confidence interval 1.280-12.301; P=.017); chemotherapy (OR=3.687, 95% CI 1.048-12.972; P=.042); preoperative MRONJ duration ≥12months (OR=7.616, 95% CI 1.865-31.110; P=.005); lesion location in maxilla (OR=1.150, 95% CI 1.006-1.315; P=.041); lesion location in posterior jaw, that is, in molar area (OR=1.384, 95% CI; 1.118-1.715; P=.003); and serum albumin <40g/L (OR=6.257, 95% CI 1.313-29.815; P=.021).
Age ≤65years, chemotherapy, preoperative MRONJ duration ≥12months, lesion location in maxilla, lesion location in the molar area, and serum albumin <40g/L may increase the risk for severe MRONJ.
Age ≤65 years, chemotherapy, preoperative MRONJ duration ≥12 months, lesion location in maxilla, lesion location in the molar area, and serum albumin less then 40 g/L may increase the risk for severe MRONJ.
Cone-beam computed tomography (CBCT) offers the advantage of a 3-dimensional representation of the anatomic relationship of the mandibular third molar tooth and the inferior alveolarcanal (IAC), as compared to a panoramic radiograph. We hypothesized that a novel method of categorizing the degrees of compression of the IAC were reliable predictors for postoperative nerve injuries.
We conducted a retrospective analysis of the outcomes in third molar surgery for patients who obtained a CBCT scan in additional to a plain film radiograph over a 12months period and underwent surgical removal of their mandibular third molars; 257 consecutive patients were identified, and 416 mandibular third molars were surgically removed.
Patients who had severe compression of the inferior alveolar canal (IAC) on CBCT imaging had a significantly increased risk of a postoperative IAN injury (P=.0068, OR=3.47, 95% CI 1.40 to 8.54) and accounted for 52.17% of all IAN injuries. Ninety-one percent of all cases of postoperative ner addition to patient factors, assessment of the degree of compression on a preoperative CBCT image is a useful tool for predicting outcomes in mandibular third molar surgery. L-α-Phosphatidylcholine mw In cases of severe compression of the IAC, patients are at a significantly increased risk of postoperative IAN injury.Lung-volume-reduction-surgery is a well-stablished treatment for pulmonary emphysema; however, lobectomy is performed unfrequently in this indication. In a 48-years-old female with COPD stage GOLD IIIC with previous lower bilobectomy due to severe poststenotic pneumonia and multiple ineffective endobronchial-valves placements lower lobe lobectomy as LVRS was performed via anterolateral thoracotomy. FEV1 increased from 0,9l (31%) preoperative to 1,74l (59%) postoperative. This case demonstrates that in well selected patients, lobar resection for emphysema is feasible with good functional outcome even in patients after previous contralateral anatomic resection.Epithelioid hemangioendothelioma is a rare malignant vascular sarcoma. Here we present a patient with a very large tumor arising from the superior vena cava (SVC), in whom a resection with negative margins was accomplished using veno-venous bypass and bovine pericardial patch reconstruction of the SVC.Compensatory sweating (CS) is the most common and disabling complication of endoscopic thoracic sympathectomy and represents an unmet clinical challenge. Our surgical hypothesis is to generate a parallel pathway to the damaged part of the sympathetic nerve, similar to the Kuntz nerve, by reconstructing the 2 healthy intercostal nerves, thus treating CS. Here, we present a novel videothoracoscopic technique involving bilateral intercostal nerve reconstruction in patients with severe CS after endoscopic thoracic sympathectomy.