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Thomas Woods posted an update 6 months, 3 weeks ago
These findings provide a new opportunity to develop selective materials and devices for applications such as efficient recognition, extraction and separation of target metal ions in complex aqueous environments.The development and application of photocatalysts with strong redox ability to degrade refractory pesticides is the key to eliminating pesticide contamination. In this work, we develop a facile, time-saving, and surfactant-assisted method to fabricate a new Z-scheme heterojunction based on TiO2/BiOCl. This photocatalyst is rich in oxygen vacancy defects (TiO2-OV-BiOCl), and displays an excellent photocatalytic degradation performance for imidacloprid (IMD), and a possible degradation pathway of IMD is provided. The surfactant F127 plays an essential role in regulating the oxygen vacancy defects (OVDs) of TiO2-OV-BiOCl, where the OVD mainly exists in 5 layer BiOCl ultrathin nanosheets. Free radical trapping experiments demonstrate that the introduction of an OVD in BiOCl as a ‘charge mediator’ changes the charge-transfer mode from a type-II mechanism to a Z-scheme mechanism. The formation of a Z-scheme heterojunction leads to an excellent light utilization and higher separation efficiency of photogenerated charge carriers with a prolonged lifetime compared to those of BiOCl and TiO2/BiOCl. This work highlights the critical role of an OVD in the construction of a Z-scheme heterojunction of TiO2/BiOCl, and it can be applied to construct efficient photocatalytic systems for pesticide degradation.Combining microfluidic devices with nuclear magnetic resonance (NMR) has the potential of unlocking their vast sample handling and processing operation space for use with the powerful analytics provided by NMR. One particularly challenging class of integrated functional elements from the perspective of NMR are conductive structures. Metallic electrodes could be used for electrochemical sample interaction for example, yet they can cause severe NMR spectral and SNR degradation. These issues are more entangled at the micro-scale since the distorted volume occupies a higher ratio of the sample volume. In this study, a combination of simulation and experimental validation was used to identify an electrode geometry that, in terms of NMR spectral parameters, performs as well as for the case when no electrodes are present. Apoptosis inhibitor By placing the metal tracks in the side-walls of a microfluidic channel, we found that NMR RF excitation performance was actually enhanced, without compromising B0 homogeneity. Monitoring in situ deposition of chitosan in the microfluidic platform is presented as a proof-of-concept demonstration of NMR characterisation of an electrochemical process.Air-free glassware and techniques are used in most organometallic research laboratories, but their relative effectiveness has not been well studied. We report a method for quantitatively comparing air and moisture exclusion by air-free glassware. Samples of benzophenone dianion in various glassware are monitored by video as their purple color is quenched. Numerical values for time until colorless are extracted from the video data and interpreted as a relative measure of air and moisture exclusion. Low pressure/vacuum (LPV) NMR tubes demonstrated by far the best performance, compared to a variety of Schlenk flasks and standard NMR tubes. The findings are of immediate practical use for synthetic chemists, and the evaluation methods can be used by individual laboratories to assess other conditions for air and moisture exclusion.Metal-organic frameworks (MOFs) with low-dimensional, deformable haloplumbate secondary building units (SBUs) are an emerging class of intrinsic white-light emitters combining advantageous properties of both MOFs and lead perovskites. Herein, we have successfully synthesized two MOFs with haloplumbate SBUs occupying an extremely high degree of structural strain with local zigzag Pb-X-Pb-X (X = Cl/Br) connectivity located in single-stranded helices. Thus, the electron-phonon coupling in the deformable SBUs affords intrinsic white-light emission and moderately high external photoluminescence quantum efficiencies of 12-15%, superior to our previously reported MOFs. Moreover, the excellent photocarrier diffusion properties of lead perovskites have been successfully incorporated into the MOFs with high chemical robustness in moisture (up to 90% relative humidity, RH).The substrate promiscuity of an acyltransferase is leveraged to synthesize artificial lipoproteins bearing a non-canonical PTM (ncPTM). The non-canonical functionality of these lipoproteins results in a distinctive hysteretic assembly-absent from the canonical lipoproteins-and is used to prepare hybrid multiblock materials with precise and programmable patterns of amphiphilicity. This study demonstrates the promise of expanding the repertoire of PTMs for the development of nanomaterials with a unique assembly and function………….BACKGROUND Curcumin derivative C086 (cur C086) is a potential chemotherapeutic agent for patients with osteosarcoma. In this study, the effects of cur C086 combined with cisplatin on the biological processes of osteosarcoma cells were investigated. MATERIAL AND METHODS In this study, expression of BMIL1 was detected by real-time quantitative reverse transcription polymerase chain reaction and Western blotting in MG-63 cells treated with cur C086+cisplatin. Functions of cur C086+cisplatin on proliferation ability, apoptosis response, and metastatic potential of MG-63 cells were determined by MTT, flow cytometry, Hoechst 33258 staining and Transwell assays, respectively. In additionally, expression of P16, E-cadherin, epidermal growth factor (EGFR), and Notch1 was measured by Western blotting. RESULTS Expression of BMIL1 decreased significantly in MG-63 cells treated with cur C086 (20 µM)+cisplatin (1.28 nM). Treatment with cur C086+cisplatin considerably inhibited growth, migration, and invasion potential in MG-63 cells, whereas apoptosis was obviously upregulated.