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Dalgaard Tolstrup posted an update 6 months ago
The present study is the first attempt to investigate the occurrence and distribution pattern of microplastics (MPs) in the beach sediments covering a 36 km long beach at Cox’s Bazar, Bangladesh. Fourier-transform infrared spectroscopy was used to identify the MP particles (>300 μm). The mean abundance of plastics in this study site was 8.1 ± 2.9 particles kg-1. The abundance of MPs in the sediments was found in the following order Fragments>Fibers>Foams>Beads>Films. The most abundant polymer types were Polypropylene (PP) (47%) and Polyethylene (PE) (23%). Most of the PP was atactic, while the low-density and high-density PE were in the balance. A higher abundance of MPs was observed in the wrack line compared to the other zones across the shore. The designated public tourist spots corresponding to few sampling sites showed significantly (P less then 0.05) higher MPs than the sites with no tourist activity.Biological trait analysis (BTA) has been proved to be a powerful tool to evaluate marine water quality. The species trait distributions of biofilm-dwelling protozoa were studied in a coastal region of the Yellow Sea, northern China, during a four-season cycle. The BTA demonstrated that (1) the protozoa showed a significant seasonal variability in biological trait pattern during the colonization process across four seasons; (2) the colonization dynamics in species trait distribution followed different temporal models; (3) the functional dynamics in spring and summer were significantly different from those in autumn and winter (P less then 0.05); and (4) functional diversity showed lower values in spring and summer than in autumn and winter. These findings suggest that BTA is subject to a high seasonal variability during colonization surveys when protozoa are used as bioindicators of marine water quality.
Drug-eluting stents impair post-angioplasty re-endothelialization thus compromising restenosis prevention while heightening thrombotic risks. We recently found that inhibition of protein kinase RNA-like endoplasmic reticulum kinase (PERK) effectively mitigated both restenosis and thrombosis in rodent models. This motivated us to determine how PERK inhibition impacts re-endothelialization.
Re-endothelialization was evaluated in endothelial-denuded rat carotid arteries after balloon angioplasty and periadventitial administration of PERK inhibitor in a hydrogel. To study whether PERK in smooth muscle cells (SMCs) regulates re-endothelialization by paracrinally influencing endothelial cells (ECs), denuded arteries exposing SMCs were lentiviral-infected to silence PERK; invitro, the extracellular vesicles isolated from the medium of PDGF-activated, PERK-upregulating human primary SMCs were transferred to human primary ECs.
Treatment with PERK inhibitor versus vehicle control accelerated re-endothelializationThe mechanism may involve paracrine factors regulated by PERK in SMCs that impact neighboring ECs. This study rationalizes future development of PERK-targeted endothelium-friendly vascular interventions.
The aims of our study were to compare cardiac magnetic resonance (CMR) scan time (time elapsed between first and last acquired sequence) and room time (time elapsed between patients’ entrance and exit of the MRI room) between sedated and non-sedated children and to assess the contributing factors.
It is a cohort study performed at a CMR facility in a tertiary-care center. We compared scan time and room time between sedated and non-sedated children and assessed the influence of gender, age, weight, height, body surface area, number of sequences, and patients’ diagnosis/previous procedures.
We included 140 children (74 sedated and 66 non-sedated), age 7.6years (3-12) and body surface area 0.83m
(0.57-1.25). The most common diagnosis/previous procedures were repaired tetralogy of Fallot, cardiomyopathies and single ventricle. Number of sequences 18 (16-22). Scan time 42min (35-54.2); room time 53min (46-63). There was difference in room time between sedated and non-sedated children (57.6±13.6 vs 52.2±15min, p<0.05), but not in scan time (47.2±14.1 vs 43.9±16min, p 0.2). The only factor associated with scan time was the number of sequences (r 0.75, p<0.001). find more The only factor associated with room time was single ventricle as indication (r 0.26, p 0.007).
Sedated children spent 5 more minutes in the CMR room than non-sedated children. Single ventricle was associated with increased room time. Number of sequences correlated with scan time. Sedation did not influence these times.
Sedated children spent 5 more minutes in the CMR room than non-sedated children. Single ventricle was associated with increased room time. Number of sequences correlated with scan time. Sedation did not influence these times.
We present a series of 20 cases of a sleeve-type injury of the distal tibia characterized by traumatic periosteal stripping caused by a high ankle sprain. We characterize the magnetic resonance imaging findings associated with this injury and highlight its association with distal tibial osteonecrosis.
We collected 20 cases of high ankle sprains with periosteal stripping of the distal tibia through teaching files and a search through our PACS database. We recorded the presence and pattern of syndesmotic ligamentous injury and the presence or absence of syndesmotic widening in patients with periosteal stripping. The presence or absence of associated fractures and osteonecrosis was noted and characterized by location.
The most commonly torn ligament was the anterior inferior tibiofibular ligament. 25% (5/20) of the patients in our series developed osteonecrosis. Osteonecrosis developed as early as 3-4weeks following the initial injury. Of the patients with osteonecrosis, 40% (2/5) had fractures of the post distal tibia.
Digital radiography has the potential to improve the practice of radiography but it also has the potential to significantly increase patient doses. Considering rapidly growing digital radiography in many centers, concerns rise about increasing the collective dose of the human population and following health effects. This study aimed to estimate organ and effective doses and calculate the lifetime attributable risk (LAR) of cancer incidence and mortality in digital radiography procedures in Iran.
Organ and effective doses of 12 routine digital radiography examinations including the skull, cervical spine, chest, thoracic spine, lumbar spine, pelvic and abdomen were estimated using PCXMC software based on Monte Carlo simulation method. Then, LARs of cancer incidence and mortality were estimated using the BEIR VII method.
Organ doses ranged from 0.01 to a maximum of 2.5mGy while effective doses ranged from 0.01 to 0.7mSv. Radiation risk showed dependence on the X-ray examination type and the patient’s sex and age.