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Aguilar Webb posted an update 6 months ago
Compared to the Historical simulation, the projections show a tendency to increase of maximum and minimum temperature in the future, and a tendency to decrease relative humidity. There is an increase in the number of days with the potential for the occurrence of the disease. The distribution of days with favorable conditions to rust disease tends to change in the future. In the Normaland Safrinhaseasons, there is a tendency to increase the number of days with favorable conditions to common rust occurrence. The influence of planting time is greater in Historical simulation when compared to future scenarios. The Safrinhaseason may present more days with the potential for the occurrence of common rust in the future than the Normalseason.We developed models for simulating trends over time as functions of the thermal index and models for estimating the levels of infestation of the coffee leaf miner and coffee berry borer and the severity of disease for coffee leaf rust and cercospora, the main phytosanitary problems in coffee crops around the world. We used historical series of climatic data and levels of pest infestation and disease severity in Coffea arabica for high and low yields for seven locations in the two main coffee-producing regions in the state of Minas Gerais in Brazil, Sul de Minas Gerais and Cerrado Mineiro. We conducted two analyses (a) we simulated the trends of the progress of diseases and pests over time using non-linear models. We only used the thermal index because air temperature is commonly measured by farmers in the regions. (b) We estimated the levels of pest infestation and disease severity using multiple linear regression, with the levels of diseases and pests as dependent variables and accumulated degree days (DD), coffee foliage (LF) estimated by DD and the number of nodes (NN) estimated by DD as independent variables. We used DD and LF = f (DD) and NN = f (DD) to predict diseases and pests with accuracy. MAPEs were 19.6, 5.7, 9.5, and 15.8% for rust, cercospora, leaf miner, and berry borer, respectively, for Sul de Minas Gerais. Establishing phytosanitary alerts using only air temperature was possible with these models.To provide a simple high-resolution heat-stress forecast for Seoul, Korea, we coupled a high-resolution climate simulation (25 m grid spacing) for an average heat day with the operational forecasting model (5 km grid spacing). Thereby, we accounted for the meso-scale weather conditions and local-scale air temperature induced by land cover and the urban heat island effect. Moreover, we estimated the impacts of heat events using heat-related mortality rate. Applying the simple high-resolution heat-stress forecast for July and August 2016, we detected a substantial spatial variability in maximum air temperature and heat-related mortality rate in Seoul. The evaluation of simulated maximum air temperature compared to observations revealed a small deviation (MB = 0.11 K, RMSD = 1.40 K). Despite the limitation of using average conditions, it was an efficient way to identify particularly affected areas, neighbourhoods, and districts for releasing more location-specific heat-stress warnings.OBJECTIVES Although cross-sectional studies have shown that ankylosing spondylitis-specific factors correlate with depressive symptom severity, the association of these factors over time is unresolved. We examined the demographic and clinical factors associated with longitudinal depressive symptom severity in AS patients. METHODS We analyzed sociodemographic, clinical, behavioral and medication data from 991 patients from the Prospective Study of Outcomes in Ankylosing spondylitis cohort, and measured depression severity with the Center for Epidemiological Studies Depression (CES-D) Scale administered at approximately 6-month visit intervals. Multivariable longitudinal negative binomial regression models were conducted using generalized estimating equation modeling to assess the demographic, clinical, and medication-related factors associated with depression severity by CES-D scores over time. find more RESULTS The median baseline CES-D score (possible range 0-60) was 10.0 (interquartile range = 5, 17). In longitudinal multivariable analyses, higher CES-D scores were associated with longitudinal smoking, greater functional impairment, greater disease activity, self-reported depression, and poor global health scores. Marital status (e.g., being married) was associated with lower CES-D. Adjusted mean CES-D scores in our model decreased over time, with a significant interaction between time and gender observed. CONCLUSION This study identified longitudinal clinical factors such as greater disease activity, greater functional impairment, and poor global health to be associated with longitudinal depression severity. These factors are potentially modifiable and may help manage depressive symptoms in AS.Renal tubular acidosis (RTA) is a normal anion gap metabolic acidosis that manifests with insufficiency of hydrogen ion excretion or bicarbonate (HCO3) reuptake as a result of renal tubular dysfunction independent of glomerular filtration rate. Hypokalemic RTA subtypes co-existing with autoimmune diseases particularly appear in Sjogren’s syndrome, but rarely in systemic lupus erythematosus (SLE). Type 4 RTA associated with hyperkalemia is very rare during the course of SLE and hence has been scarcely reported in the literature. Here, we report a 42-year-old patient for whom regular follow-up was ongoing due to class IV lupus nephritis when she developed hyperkalemia. The patient had normal anion gap hyperkalemic metabolic acidosis and her urine pH was 5.5. Type 4 RTA was considered and, therefore, tests for renin and aldosterone levels were requested, which revealed that renin was suppressed and aldosterone was decreased. Upon diagnosis of SLE-associated type 4 RTA, short-term oral HCO3 and fludrocortisone were initiated. Potassium (K) and HCO3 levels improved at day 15 of therapy. In this review, we analyzed our case along with five other reports (a total of seven cases) of SLE-associated type 4 RTA we identified through a literature search. We wanted to highlight RTA for differential diagnosis of hyperkalemia emerging during SLE/lupus nephritis and we also discussed possible underlying mechanisms.