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Filtenborg Horowitz posted an update 6 months, 2 weeks ago
Two new N-acetyl-ᴅ-glucosamine derivatives, penichryfurans A (1) and B (2), were obtained from the fermentation of an endophytic fungus Penicillium chrysogenum which inhabited the marine medical red alga Grateloupia turuturu. Their structures were established by detailed spectroscopic analysis of 1D and 2D NMR in combination with HRESIMS data. The absolute configurations were determined by the (Mo2(OAc)4)-induced CD and comparison of the calculated and experimental electronic curcular dichroism (ECD) spectra. Both compounds were evaluated for their in vitro cytotoxic activities against A549, HeLa, and HepG2 cell lines, among which compound 1 exhibited strong cytotoxicity towards the HepG2 cell line with an IC50 value of 9.0 μM.Individuals with dementia and their carers often experience a rupture of relationships that co-occurs with declining functional and cognitive abilities, leading to their increased social exclusion in both intimate relationships and community settings. While initiatives have been developed to support meaningful interaction and participation in society, they have broadly ignored the significance of how cultural factors influence experiences of inclusion/exclusion of these individuals. An ethnographic study was conducted by an interdisciplinary research team between April 2018 and January 2019 to explore the intersections of culture and social inclusion/exclusion in a culturally diverse group of persons with dementia, caregivers and staff members of a non-profit organization located in a multicultural neighborhood of a bilingual Canadian city. The participants’ culture was inextricably linked to their experiences in three overarching themes of social inclusion/exclusion transformation of the person with dementia and the caregiver; participation in social networks and meaningful relations; and styles of care provision in health and social services. Cultural mandates that prescribe practices of intergenerational care shape the way certain caregivers perceive their role and mitigated experiences of exclusion. Culturally specific notions and views associated with dementia prevalent in certain communities increased experiences of inclusion or exclusion. Engagement with the cultural elements of individuals with dementia was shown to be an effective and underexplored tool for fostering inclusion. The results of this study highlight the value of the ethnographic methods for incorporating the perspective of persons with dementia in research.Severing a mixed method study into several publications is antithetical to the purpose and principles of mixed method designs. In this editorial, I explore the ramifications of such “splitting”.When looking through phenomenology articles in human science and philosophy journals, we may be excused to get the impression that they offer an inconsistent array of phenomenology publications. In this article, we describe three simple but helpful distinctions for determining some order first, the great foundational publications; second, exegetical publications in the wake of the great works; and third, phenomenological studies done directly on phenomena. Our aim in this article is not to lay claim to phenomenology as a label but rather to discuss how “doing phenomenology directly on the phenomena and the things” means taking up a certain attitude and practicing an attentive awareness to the things of the world as we live and experience them. We propose that engaging in philosophical exegesis and argumentation is not very helpful for analyzing and explicating originary meanings of experiential phenomena. And we show how doing phenomenology directly on the things can be facilitated by a phenomenologically inspired interpretive attitude as well as by a sensitive talent for employing phenomenological examples.Medical tourism is an expanding phenomenon. Scientific studies address the changes and challenges of the present and future trend. However, no research considers the study of bibliometric variables and area of business, management and accounting. Linderalactone manufacturer This bibliometric analysis discovered the following elements (1) The main articles are based on guest services, management, leadership principles applied, hotel services associated with healthcare, marketing variables and elements that guide the choice in medical tourism; (2) The main authors do not deal with tourism but are involved in various ways in the national health system of the countries of origin or in WHO; (3)cost-efficiency and analytical accounting linked to medical tourism structures and destination choices are not yet developed topics.
The ability of people to infer intentions from movement of other vessels was investigated. Across three levels of variability in movements in the path of computer-controlled ships, participants attempted to determine which entity was hostile.
Detection of hostile intentions through spatial movements of vessels is important in an array of real-world scenarios. This experiment sought to determine baseline abilities of humans to do so.
Participants selected a discrete movement direction of their ship. Six other ships’ locations then updated. A single entity displayed one of two hostile behaviors shadowing, which involved mirroring the participant’s vessel’s movements; and hunting, which involved closing in on the participant’s vessel. Trials allowed up to 35 moves before identifying the hostile ship and its behavior. Uncertainty was introduced through adding variability to ships’ movements such that their path was 0%, 25%, or 50% random.
Even with no variability in the ships’ movements, accurate detection was low, identifying the hostile entity about 60% of the time. Variability in the paths decreased detection. Detection of hunting was strongly degraded by distance between ownship and the hostile ship, but shadowing was not. Strategies employing different directions of movement across the trial, but also featuring some runs of consecutive movements, facilitated detection.
Early identification of threats based on movement characteristics alone is likely to be difficult, but particularly so when adversaries employ some level of uncertainty to mask their intentions. These findings highlight the need to develop decision aids to support human performance.
Early identification of threats based on movement characteristics alone is likely to be difficult, but particularly so when adversaries employ some level of uncertainty to mask their intentions. These findings highlight the need to develop decision aids to support human performance.
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