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Bentsen Richardson posted an update 6 months, 3 weeks ago
Together, our findings suggest that the poor productivity of declining puffin populations in the north-east Atlantic is driven by breeding adults being forced to forage far from the colony, presumably because of low prey availability near colonies, possibly amplified by intraspecific competition. Our results provide valuable information for the conservation of this and other important North-Atlantic species and highlight the potential of multi-population approaches to answer important questions about the ecological drivers of population trends.
To explore the relationship between parents’ practices and the oral health-related quality of life of children according to the child’s point of view.
It is a cross-sectional study with all children (response rate 75.6 percent, n = 329) from fourth grade of Elementary School to the third grade of High School in 2016 in a small city of southern Brazil. Oral health related quality of life was measured using the oral impact on daily performances (OIDP) using the prevalence of any impact as outcome (OIDP score > 0). Seven parenting practices were evaluated by the inventory of parenting Styles for both father and mother. buy Sevabertinib Logistic regression models were fitted to estimate the association of each parenting practice with OIDP score > 0, and adjusted by sex, age, family equivalent income, mother and father’s educational level.
About 55.3 percent of the children had at least one impact on daily performances. Respectively, the parenting practices with the highest and lowest percentage for both parents’ risk behavior was physical abuse (28.8 percent) and negative monitoring (7.8 percent), while families in which both parents’ risk behavior for negligence was 14.7 percent. In the adjusted models, families in which both parents’ risk behavior on negligence and physical abuse (OR = 2.16, 95%CI 1.13-4.19) and (lack of) positive monitoring (OR = 2.99, 95%CI 1.32-7.40) had a greater impact on daily life compared to those in which no parents’ had risk behavior.
Having any impact on OIDP was associated with negligence, physical abuse, and lack of monitoring among children and adolescents.
Having any impact on OIDP was associated with negligence, physical abuse, and lack of monitoring among children and adolescents.Glucocorticoid treatment increases venous thromboembolism (VTE) risk. Whether this is due to the medication or the underlying disease, or affects the risk of VTE recurrence, has been difficult to determine. The aim of our present study was to quantify the risk for first and recurrent VTE associated with oral glucocorticoids use, considering the underlying disease. A total of 2547 patients with VTE from the Multiple Environmental and Genetic Assessment of Risk Factors for Venous Thrombosis (MEGA) study were linked to the Dutch Pharmaceutical Statistics register. The risk of first VTE during periods of exposure with oral glucocorticoids was estimated by the self-controlled case series method and that of recurrent VTE was examined in a cohort design. The incidence rate ratio (IRR) of first VTE in the period of glucocorticoid treatment was 3·51 . This IRR was 2·53 (95% CI 1·10-5·72) in the week before treatment started, 5·28 (95% CI 2·89-9·53) in the first 7 days of treatment, remained elevated afterwards and decreased to 1·55 (95% CI 0·85-3·12) after 6 months, as compared to unexposed periods. The hazard ratio for recurrence was 2·72 (95% CI 1·64-4·78) in treatment periods as compared with no treatment. The increased risk of VTE associated with oral glucocorticoid treatment is due to a combined effect of the treatment and the underlying disease, remaining high during the first months of prescription.Intervening early during childhood and adolescence to prevent mental health problems from becoming chronic, or even to prevent them occurring at all, has become an increasingly popular approach within the field of mental health over the past three decades. The importance of, and potential for, early preventive interventions in infancy, the pre-natal period and even pre-conception is highlighted by several of the papers featured in the current issue of the Journal, which are summarised in this editorial. Identifying children most at risk of mental illness in order to selectively target preventive efforts and carefully testing the effectiveness of these interventions, particularly in low-and middle-income country contexts, are crucial next steps as we move towards an era of more personalised and earlier prevention and intervention in mental health.Neurodevelopmental disorders are widely acknowledged to be complex and multifactorial in origin, but this is rarely reflected in the approaches used to study them. We reflect on the 2021 Annual Research review and its introduction of a new conceptual framework designed to make the complexity of early neurodevelopment more empirically tractable. We evaluate the review authors’ justification, explanation, and guidance for implementation of their framework in the context of their stated goals and highlight key assumptions that support its conceptual validity. Finally, we offer a genetic epidemiological perspective on potential applications, suggesting ways in which genomic data can be used to elucidate causal mechanistic processes within the AMEND framework.Multiple sclerosis (MS) is a challenging and disabling condition, predominantly affecting individuals in their early life, and has an impact functionally, financially, and on quality of life. However, there is a lack of systematic approach towards assessing socioeconomic consequences of MS. Our objective was to systematically review observational analytical studies investigating the socioeconomic consequences of MS. We conducted a systematic review on socioeconomic consequences of MS with a focus on employment-, income-, work ability- and relationship-related outcomes between MS and the general population. Additionally, the educational characteristics were extracted. From 4958 studies identified, 187 were assessed for eligibility and a total of 27 studies from eight countries were included in this qualitative assessment; 32 different outcomes were identified. All studies indicated pronounced differences between MS patients and the general population, for example 15%-30% lower employment, lower earnings and higher social benefits, higher absenteeism and presenteeism proportions, higher work disability (eg, sick-leave days) among MS patients.
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