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Weaver Otte posted an update 6 months ago
uicide risk, potentially important for incorporation in clinical practice for suicide.Methanogenesis is a widespread metabolism of evolutionary and environmental importance that is likely to have originated on early Earth. Microorganisms that perform methanogenesis, termed methanogens, belong exclusively to the domain Archaea. Despite maintaining eukaryotic transcription machinery and homologs of bacterial regulators, archaeal transcription and gene regulation appear to be distinct from either domain. While genes involved in methanogenic metabolism have been identified and characterized, their regulation in response to both extracellular and intracellular signals is less understood. Here, we review recent reports on transcriptional regulation of methanogenesis using two model methanogens, Methanococcus maripaludis and Methanosarcina acetivorans, and highlight directions for future research in this nascent field.The outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts contain β-barrel integral membrane proteins. In bacteria, the five-protein β-barrel assembly machine (Bam) accelerates the folding and membrane integration of these proteins. The central component of the machine, BamA, contains a β-barrel domain that can adopt a lateral-open state with its N-terminal and C-terminal β-strands unpaired. Recently, strategies have been developed to capture β-barrel folding intermediates on the Bam complex. Biochemical and structural studies provide support for a model in which substrates assemble at the lateral opening of BamA. In this model, the N-terminal β-strand of BamA captures the C-terminal β-strand of substrates by hydrogen bonding to allow their directional folding and subsequent release into the membrane.We examine the explanatory and forecasting power of economic growth, financial development, trade openness and FDI for CO2 emissions in major developed economies within the context of the debate on curbing CO2 emissions Post-Paris Agreement (COP21). buy FX-909 Using data from G-6 countries from 1978 to 2014 and employing a set of empirical approaches, we find weak evidence of the Environmental Kuznets Curve, while economic growth, capital market expansion, and trade openness are found to be major drivers of carbon emissions. Carbon emissions are also weakly and negatively affected by stock market capitalization and FDI. Moreover, the forecasting performance is quite good, particularly by augmenting the model with energy consumption and oil prices. With respect to climate commitments, our empirical findings reveal important policy implications.Strategic management of complex decisional problems in the tourism sector requires the implementation of proper planning procedures for sustainable tourism activities, due to either the number of actors involved, the presence of conflicting goals and the need of resource rationalization. Thus, the aim of the research is to implement a new approach for the selection of projects to be funded by public administration, in order to maximize the efficiency of public resource allocation. Furthermore, the proposed technique enhances the inclusion of the three dimensions of sustainability in tourism policy planning and implementation phases. The Multi-objective Optimization model accounts for environmental, social and economic impacts, to select tourism activities to be realized in order to maximize stakeholder utility. In order to test the model, we selected a case study a call for tender drafted by an Italian Public administration, whose aim was to support the attractiveness of the urban areas. Findings illustrate that, in comparison with multicriteria techniques, the proposed model allows to achieve a better allocation of public funds, in both quantitative (i.e., amount of resources allocated) and qualitative (selection of projects with positive social and environmental implication) terms.Freshwater lakes are dynamic ecosystems and provide multiple ecosystem services to humans. Sudden changes in lake environmental conditions such as cyanobacterial blooms can negatively impact lake usage. Automated high-frequency monitoring (AHFM) systems allow the detection of short-lived extreme and unpredictable events and enable lake managers to take mitigation actions earlier than if basing decisions on conventional monitoring programmes. In this study a cost-benefit approach was used to compare the costs of implementing and running an AHFM system with its potential benefits for three case study lakes. It was shown that AHFM can help avoid human health impacts, lost recreation opportunities, and revenue losses for livestock, aquaculture and agriculture as well as reputational damages for drinking water treatment. Our results showed that the largest benefits of AHFM can be expected in prevention of human health impacts and reputational damages. The potential benefits of AHFM, however, do not always outweigh installation and operation costs. While for Lake Kinneret (Israel) over a 10-year period, the depreciated total benefits are higher than the depreciated total costs, this is not the case for Lough Gara (Ireland). For Lake Mälaren in Sweden it would depend on the configuration of the AHFM system, as well as on how the benefits are calculated. In general, the higher the frequency and severity of changes in lake environmental conditions associated with detrimental consequences for humans and the higher the number of lake users, the more likely it is that the application of an AHFM system is financially viable.Most studies of urban forest management look at vegetation on public land. Yet, to meet ambitious urban forest targets, cities must attempt to maintain or increase trees and canopy cover on private urban land too. In this study, we review and evaluate international approaches to protecting and retaining trees on private urban land. Our study combines a systematic academic literature review, two empirical social science studies on the views of urban forest professionals, and a global case study review of innovative regulations and incentives aimed at protecting and retaining trees on private urban land. Case studies were evaluated for the extent they exceeded minimum standards or went beyond ‘business-as-usual’. We found that the most innovative mechanisms combine many regulations, instead of relying on a single regulation, and use financial incentives to retain or plant trees in newly developed or re-developed sites, as well as private residences. We did not find any cases where appropriate monitoring was in place to determine the efficacy and efficiency of these mechanisms.
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