• Kara Parks posted an update 6 months ago

    Comprehensive evaluations on datasets from the particle tracking challenge demonstrate the competitiveness of the proposed deep-learning method compared to the state of the art. Additional tests on real-time-lapse fluorescence microscopy images of various types of intracellular particles show the method performs comparably with human experts.

    The software code implementing the proposed method as well as a description of how to obtain the test data used in the presented experiments will be available for non-commercial purposes from https//github.com/yoyohoho0221/pt_linking.

    Supplementary data are available at Bioinformatics online.

    Supplementary data are available at Bioinformatics online.

    Immediate fixed full-arch implant-supported prosthetic rehabilitation of the severely atrophic maxilla is a challenging treatment modality with favourable patient interest. The delivery of the treatment is challenging due to the difficulty in providing adequate posterior implant positioning with high primary stability in the absence of alveolar bone distal to the maxillary lateral incisors. Current trends in posterior implant placement and immediate loading include the placement of zygomatic implants or distally tilted implants placed anterior to the sinus cavity. The development of an extended-length subcrestal angulated implant gives an additional option to provide posterior occlusal support for reconstruction of the severely atrophic maxilla with an immediate full-arch fixed prosthesis.

    This article describes a trans-sinus nasal protocol for fixed full-arch rehabilitation in the severely atrophic maxilla when the residual alveolar bone does not extend distally from the permanent maxillary lateral incisors. The extended-length distally tilted implant transverses a simultaneously augmented sinus cavity and engages the anterior maxilla and bone of the lateral nasal wall.

    The placement of an extended-length distal tilted implant placed the implant head at the crest of the alveolar ridge in the first permanent molar position, promoting favourable prosthetic biomechanics for a full-arch fixed prosthesis. Passivity of fit of the fixed prosthesis was achieved due to the 24-degree subcrestal angulation feature of the implant and use of multi-unit abutments.

    The placement of an extended-length distal tilted implant placed the implant head at the crest of the alveolar ridge in the first permanent molar position, promoting favourable prosthetic biomechanics for a full-arch fixed prosthesis. Passivity of fit of the fixed prosthesis was achieved due to the 24-degree subcrestal angulation feature of the implant and use of multi-unit abutments.

    To investigate the influence of vertical mucosal thickness on marginal bone loss around implants with short and long prosthetic abutments and the marginal bone loss progression rate up to 18 months after prosthetic loading.

    Internal hex platform-switched implants were placed equicrestally using a two-stage protocol in the posterior mandible of two groups of patients with different vertical mucosal thickness, thin (≤ 2.0 mm) and thick (> 2.0 mm). Elevated prosthetic abutments of different heights (1 mm or 3 mm) were randomly assigned for single screw-retained crowns in both groups. Mesial and distal marginal bone loss were measured at implant placement (T0) and crown delivery (after 4 months ), and after 6 (T2), 12 (T3) and 18 months (T4) of functional loading.

    Eighty implants were placed in eighty patients. Three patients dropped out at T2. At T4, 74 out of 77 implants were functioning, resulting in a 96% survival rate. check details Marginal bone loss (mean ± SE) at T2 was significantly greater in the 1-mm abutment groups (0.61 ± 0.09 mm with thin mucosa; 0.64 ± 0.07 mm with thick mucosa) than in the 3-mm abutment groups (0.32 ± 0.07 mm with thin mucosa; 0.26 ± 0.04 mm with thick mucosa). The marginal bone loss pattern over 18 months of loading showed that the greatest amount of marginal bone loss occurred during the first 6 months of function.

    Internal hex platform-switched implants placed equicrestally and restored with 1-mm abutments presented greater marginal bone loss than identical implants with 3-mm abutments, with vertical mucosal thickness having no significant influence.

    Internal hex platform-switched implants placed equicrestally and restored with 1-mm abutments presented greater marginal bone loss than identical implants with 3-mm abutments, with vertical mucosal thickness having no significant influence.

    To compare the short-term clinical and radiographic outcomes of angulated screw-retained and cemented implant crowns following flapless immediate implant placement.

    The study was designed as a prospective cohort study with 1-year follow-up. Eligible patients were divided into two groups according to restoration type the angulated screw group (AG) and the cemented group (CG). Implant survival, marginal bone loss, mechanical complications, probing depth, bleeding on probing% and pink aesthetic score were evaluated.

    After 1 year of loading, the implant survival rate was 100% in both groups (AG, n = 23; CG, n = 20). A significantly lower bleeding on probing% was found in the AG than in the CG (11.6 ± 19.1% vs. 33.3 ± 33.8%, P = 0.04). No significant differences in marginal bone loss, probing depth and mechanical complication rates were found between the two groups (P = 0.53, 0.48, 0.41, respectively). The overall pink aesthetic score value was 8.96 ± 0.88 in the AG and 8.98 ± 0.62 in the CG at 1-year examination (P = 0.96). The percentage of excellent pink aesthetic scores (≥ 9) value increased from 48% at baseline to 83% at 1 year in the AG, and from 45% at baseline to 85% at 1 year in the CG.

    Based on the 1-year results, both treatment options provide high implant survival, a stable marginal bone level and excellent aesthetic outcomes in the short term. Angulated screw-retained crowns might benefit the long-term peri-implant conditions.

    Based on the 1-year results, both treatment options provide high implant survival, a stable marginal bone level and excellent aesthetic outcomes in the short term. Angulated screw-retained crowns might benefit the long-term peri-implant conditions.

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