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Pena Crews posted an update 6 months ago
Both simulation with fluoro-2-deoxy-D-glucose (FDG) and preclinical data with FDG and raclopride were used to evaluate the proposed framework. The results showed that our 4D DIP framework quantitatively and qualitatively outperformed 3D DIP and other unsupervised denoising methods. The proposed 4D DIP framework thus provides a promising procedure for dynamic PET image denoising.Charging of insulators modifies local electric field distribution and increases potential threat to the safety of the gas insulated equipment. In this paper, surface charge tailoring techniques are classified and reviewed by introducing a Dam-flood model. Technical solutions of different charge tailoring methods are compared and discussed. The outlook of potential solutions to suppress charge accumulation is recommended and discussed based on industrial consideration. This paper serves as a guide handbook for engineers and researchers into the study of charge tailoring methods. Meanwhile, we hope that the content of this paper could shed some lights upon charge-free insulators to promote the industrial application of HVDC GIL/GIS.The aim of this report is to synthesize copper oxide nanocubes (CuO NCs) at room temperature, using sodium borohydride as a reducing agent, and Cetyl Trimethyl Ammonium Bromide (CTAB) as a stabilizing agent. The crystallinity and morphology of the synthesized CuO NCs are investigated via X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscope (TEM). The optical properties were analyzed by means of UV-visible absorbance and Raman spectroscopy. The existence of specific functional groups and structural stability were established via FTIR spectroscopy and thermogravimetric analysis (TGA). Furthermore, the catalytic efficiency of the as-prepared CuO NCs was tested using catalytic and photocatalytic studies of para-nitrophenol (p-NP) reduction and methylene blue (MB) degradation, respectively. The catalytic results demonstrated the nanocubes’ excellent catalytic and photocatalytic responses with respect to the abatement of p-NP and MB within 50 s and 240 min, with kinetic rate constants of 3.9 × 10-2 s-1 and 6.47 × 10-3 min-1, respectively.
To introduce the concept of statistical shape model (SSM)-based planning organ-at-risk volume (sPRV) for pancreatic cancer patients.
A total of 120 pancreatic cancer patients were enrolled in this study. Selleckchem AMG PERK 44 After correcting inter-patient variations in the centroid position of the planning target volume (PTV), four different SSMs were constructed by registering a deformable template model to an individual model for the stomach and duodenum. The sPRV, which focused on the following different components of the inter-patient variations, was then created Scenario A shape, rotational angle, volume, and centroid position; Scenario B shape, rotational angle, and volume; Scenario C shape and rotational angle; and Scenario D shape. The conventional PRV (cPRV) was created by adding an isotropic margin R (3-15 mm) to the mean shape model. The corresponding sPRV was created from the SSM until the volume difference between the cPRV and sPRV was less than 1%. Thereafter, we computed the overlapping volume between the PTV and cPRV (OL
) or sPRV (OL
) in each patient. OL
being larger than OL
implies that the local shape variations in the corresponding OAR close to the PTV were large. Therefore, OL
/OL
was calculated in each patient for each R-value, and the median value of OL
/OL
was regarded as a surrogate for plan quality for each R-value.
For R=3 and 5 mm, OL
/OL
exceeded 1 for the stomach and duodenum in all scenarios, with a maximum OL
/OL
of 1.21. This indicates that smaller isotropic margins did not sufficiently account for the local shape changes close to the PTV.
Our results indicated that, in contrast to conventional PRV, SSM-based PRVs, which account for local shape changes, would result in better dose sparing for the stomach and duodenum in pancreatic cancer patients.
Our results indicated that, in contrast to conventional PRV, SSM-based PRVs, which account for local shape changes, would result in better dose sparing for the stomach and duodenum in pancreatic cancer patients.Electrohydrodynamic jet (E-Jet) printing is a powerful technique for micro/nanostructure fabrication with high resolution and efficiency. However, conventional E-Jet printing are still limited in printing accuracy and ink adaptability due to the nozzle clogging effect. In this paper, we develop a nano-tip focused electrohydrodynamic jet (NFEJ) method to print high-resolution structures. The Ni cantilever nanoprobes with nanoscale radius of curvature (ROC) on their tips were manufactured by a facile and scalable method using silicon template and micro-electroforming technique. Scanning electron microscope was used to analyse the micromorphology of the silicon template with inverted pyramid pits, which was obtained from anisotropic wet etching of silicon. Electroforming mold was obtained by photolithography and plasma etching which divide the top side of Ni film into isolated cantilever pits. Ni cantilever nanoprobes with an average tip ROC of about 48 nm were achieved by the subsequent micro electroforming process. High-resolution droplets array with an average diameter of about 890 ± 93 nm were printed by the NFEJ printing head equipped with these Ni nanoprobes, which verified the practicality of the developed Ni nanoprobes for NFEJ printing.Magnetic particle imaging (MPI) is a promising medical imaging technique for visualizing the three-dimensional distribution of tracer materials, specifically iron oxide nanoparticles (IONP). The optimization of magnetic nanoparticles (MNP) plays an essential role to improve the image resolution and sensitivity of imaging techniques.
In this work, the optimization of commercial IONP (EMG 700, Ferrotec) coated with anionic surfactants was carried out using magnetic separation (MS) technique, by a low gradient magnetic separation (LGMS) (<15 T m
) method, to improve their performance as MPI tracers.
The magnetophoretical behavior of the samples in different concentrations ranging from 2 to 120 mmol l
was investigated over 24 h of separation. The samples were characterized by dynamic light scattering (DLS), AC susceptibility (ACS), magnetic particle spectroscopy (MPS) and they were imaged in a preclinical MPI scanner, before and after MS.
DLS results showed that by increasing the concentration from 2 to 120 mmol l
the hydrodynamic diameter of MNP decrease from 75 to 47 nm and size distribution decrease from 0.