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Upchurch Warren posted an update 7 months, 2 weeks ago
Animal manure, agricultural residues, and other sources of biomass can be diverted from the waste stream and composted into valuable fertilizer. However, composting often results in substantial N loss through NH3 gas volatilization. We investigated biochar’s capacity to improve NH3 -N retention during composting of poultry manure and straw. After 7 wk, total N loss from composting with unoxidized biochar was twofold and sixfold higher than N loss from composting with oxidized biochar and without biochar (307, 142, and 51 mg N g-1 N in the initial compost feedstocks, respectively). When cumulative NH3 -N loss was calculated relative to CO2 -C loss to account for differences in microbial activity, NH3 -N/CO2 -C loss from compost with oxidized biochar was 55% lower than from compost with unoxidized biochar (82% lower based on mass balance). Oxidized biochar particles removed from compost after 7 wk retained 16.0 mg N g-1 biochar, compared with only 6.1 mg N g-1 retained by unoxidized biochar, suggesting that N retention by biochar particles provides a mechanism for reduced NH3 -N loss. These data show that oxidized biochar enhanced microbial activity, doubled composting rate, and reduced NH3 -N loss compared with unoxidized biochar and that biochar’s physiochemical characteristics modulate its performance in compost. In particular, the presence of oxidized surface functional groups, which can be increased artificially or through environmental weathering, appear to play an important role in key compost processes. This has implications for other natural and managed systems where pyrogenic organic matter may mediate biological activity and nutrient cycles.
Cystic fibrosis (CF) carrier screening should be offered to people planning a pregnancy or in early pregnancy, according to current recommendations. However, research indicates rates of offering CF carrier screening are low. Health professionals (HPs) play an important role in offering population carrier screening.
To determine the opinions, knowledge and practice patterns of HPs with regard to the routine offering of population carrier screening for CF.
Five key informant interviews informed the development of an online questionnaire which was distributed to a select group of HPs involved in prenatal care in Victoria, Australia.
Of the participants who completed the questionnaire (n=87), 35.6% reported offering CF carrier screening to all patients attending for preconception or early pregnancy consultations. High referrers of CF carrier screening were more likely to be female, work in the private sector, in metropolitan areas and specialise as an obstetrician. High referrers demonstrated a greater level of knowledge of CF and carrier screening than low referrers (t=-3.779, P<0.001). Low referrers perceived more barriers to offering carrier screening than high referrers (t=2.125, P=0.037). Low referrers were more likely to perceive lack of community awareness and HP knowledge as a barrier to offering CF carrier screening, compared to high referrers, who were more likely to perceive time constraints as a barrier.
To promote routine offering of population CF carrier screening, resources are needed to improve knowledge and provide clinical support thereby reducing perceived barriers.
To promote routine offering of population CF carrier screening, resources are needed to improve knowledge and provide clinical support thereby reducing perceived barriers.Ubiquitin-specific protease 14 (USP14) is a ubiquitin-specific protease that is associated with the proteasome and plays important roles in cellular functions, viral infection, inflammatory responses, neurodegenerative diseases, and tumorigenesis. USP14 appears to have a dual function in regulating intracellular proteolytic degradation. USP14 impedes degradation of ubiquitinated proteins by removing ubiquitin chains from its substrates, while it could promote protein degradation via increasing proteasome activation. Increasing evidence has shown that USP14 is also involved in the regulation of autophagy. https://www.selleckchem.com/products/odm208.html Thus, USP14 might act as a key regulator in two major intracellular proteolytic pathways the ubiquitin-proteasome system (UPS) and autophagy. The important roles of USP14 in multiple diseases have encouraged the development of clinically viable USP14 antagonists. This review summarizes the current state of knowledge about the regulation of USP14 expression, activity, and its functions in physiological and pathological processes.Carbon (C) is playing an important role in regulating soil nutrient cycling, maintaining soil fertility and crop yield, but there is still need to further study on how C source utilization characteristic respond to soil physical and chemical properties change with different fertilizer treatments under a double-cropping rice (Oryza sativa L.) field in southern China. Therefore, the effects of 34-year long-term fertilizer regime on C source utilization characteristic in rice rhizosphere and non-rhizosphere soils under a double-cropping rice field in southern China were studied by using 18 O-H2 O method in the present paper. The field experiments were included four fertilizer treatments mineral fertilizer alone (MF), rice straw and mineral fertilizer (RF), 30% organic manure and 70% mineral fertilizer (OM), and without fertilizer input as control (CK). The results showed that microbial biomass C content, basal respiration of soil microorganism and microbial growth rate in rice rhizosphere and non-rhizosphere soicated that there had obvious difference in utilization characteristic of soil microorganism to exogenic C source among different fertilizer treatments. In conclusion, this results indicated that characteristic of soil C source utilization were significantly changed under different long-term fertilizer condition.The additive genetic variation (VA ) of fitness in a population is of particular importance to quantify its adaptive potential and predict its response to rapid environmental change. Recent statistical advances in quantitative genetics and the use of new molecular tools have fostered great interest in estimating fitness VA in wild populations. However, the value of VA for fitness in predicting evolutionary changes over several generations remains mostly unknown. In our study, we addressed this question by combining classical quantitative genetics with experimental evolution in the model organism Tribolium castaneum (red flour beetle) in three new environmental conditions (Dry, Hot, Hot-Dry). We tested for potential constraints that might limit adaptation, including environmental and sex genetic antagonisms captured by negative genetic covariance between environments and female and male fitness, respectively. Observed fitness changes after 20 generations mainly matched our predictions. Given that body size is commonly used as a proxy for fitness, we also tested how this trait and its genetic variance (including nonadditive genetic variance) were impacted by environmental stress.
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