• Crowley Brown posted an update 6 months, 3 weeks ago

    Moreover, the model predicted that the higher pressures (P > 1.5 MPa) would intensify the inhibition of N2 production via denitrification and result in an accumulation of ammonia in the sediment along with a decrease in dissolved oxygen. The results imply that increased hydrostatic pressure caused by dam constructions may have a strong effect on microbial nitrogen conversion, and that this may result in lower nitrogen removal.The disposal and reuse of cephalosporin mycelia dregs (CMDs) pose a great challenge to the biopharma industry, but it acts as the new source of antibiotic resistome, although agriculture intensification remains uncertain. Herein, two common cash crops (maize and soybean) were planted in the actual field, and the effects of the application of treated CMDs, chicken manure and chemical fertilizer served as control groups were both investigated according to comparison experiment. Amplicon-targeted 16S rRNA and high-throughput sequencing was analyzed for rhizosphere antibiotic resistome. Results showed that hydrothermal and spray-dried (HT + SD) CMDs could promote nutrients uptake and stabilize soil fertility indicator, and finally improved the crop yield (maximum, 119.68%). The numbers and relative abundances of total ARGs in soils were not significantly different from that of conventional fertilizer (p > 0.05), but crop type marked the differences in distribution. see more The overall economic benefits are predicted to be around $373-745 million annually, considering its application to the whole country. HT + SD-treated CMDs can be therefore used as a high-quality and safe alternative fertilizer for agriculture use. These findings are expected to offer a fresh perspective on the application of antibiotic fermentation residue (AFR) in the future.Chronic kidney disease of unknown etiology (CKDu) is an epidemic that affects young agricultural workers in several warm regions of the world. However, there is a lack of monitoring of kidney issues in regions with extremely warm environments such as the Northwest of Mexico, a semi-arid region with a growing agricultural industry, where migrant and seasonal farm workers (MSFWs) travel to work in the fields. The objective of this study was to longitudinally assess kidney functioning of MSFWs in relation to pesticide exposure, heat stress and dehydration in a large-scale farm in Mexico. We enrolled 101 MSFWs, of whom 50 were randomly selected to work in an organic certified area and 51 were randomly selected to work in a conventional area. We also enrolled 50 office workers within the same region as a reference group. We collected urine and blood samples from all workers in addition to demographic, behavioral, and occupational characteristics. The physiological strain index (PSI) was used to estimate workers’ hategory (conventional/organic MSFWs and office workers) was related to an increase in heat strain. This suggests that pesticide exposure needs to be considered in combination with heat stress and dehydration. This study provides valuable information on kidney function in MSFWs, and it shows the importance of early long-term monitoring in farm workers in other regions where CKDu has not been evaluated yet.In this paper, the heterogeneous Fenton like-reaction for Arsenic-contaminated groundwater remediation based on the performance of FeSO4 as an efficient and green catalyst and CaO2 as a source of H2O2 was investigated. To intensify the heterogeneous Fenton process, three oxidants were tested sodium percarbonate (SPC), sodium persulfate (SPS), and calcium peroxide (CP). The results showed that CP and SPC had a synergetic effect on the rate of Arsenic degradation, while SPS had an antagonistic effect. On the other hand, inorganic ions such as Na+, Mg2+ have a very low impact on the Arsenic removal efficiency, while the anions Cl- and NO3- exhibited significant inhibition of Arsenic degradation. This effect may be imputed to the reaction and conversion of hydroxyl (HO•) radicals to less reactive. Thus, HCO3- and humic acid dramatically raised the degradation rate. Also, the response Surface method based on Box-Behnken design was applied to examine the suitable modeling, and optimized condition of the Fenton like-reaction process, the maximum Arsenic removal efficiency of 94.91% is obtained when 0 = 1.97 mM, 0 = 1.74 mM and initial pH = 4.67. The obtained results showed that the Fenton-like reaction is an effective and reliable process for arsenic removal from groundwater with low non-carcinogenic risk (HQ) and carcinogenic risk (CR) values.

    Results from observational and experimental studies indicate that exposure to air pollutants during gestation reduces birth weight, whereas little is known on potential cardiometabolic consequences for the offspring at adulthood.

    Our aim was to evaluate the long-term effects of gestational exposure to diesel engine exhaust (DE) on adult offspring phenotype in a rabbit model.

    The protocol was designed to mimic human exposure in large European cities. Females rabbits were exposed to diluted (1mg/m

    ) DE (exposed, n=9) or clean air (controls, n=7), from 3 days after mating, 2h/d and 5d/wk in a nose-only inhalation system throughout gestation (gestation days 3-27). After birth and weaning, 72 offspring (47 exposed and 25 controls) were raised until adulthood (7.5 months) to evaluate their cardio-metabolic status, including the monitoring of body weight and food intake, fasting biochemistry, body composition (iDXA), cardiovascular parameters and glucose tolerance. After a metabolic challenge (high fat diet in males and gestation in females), animals were euthanized for postmortem phenotyping.

    Sex-specific responses to maternal exposure were observed in adult offspring. Age-related increases in blood pressure (p=0.058), glycaemia (p=0.029), and perirenal fat mass (p=0.026) as well as reductions in HDL-cholesterol (p=0.025) and fat-to-body weight ratio (p=0.011) were observed in exposed males, suggesting a metabolic syndrome. Almost only trends were observed in exposed females with higher triglycerides and decreased bone density compared to control females. Metabolic challenges triggered or amplified some biological responses, especially in females.

    In utero exposure to air pollution predisposed rabbit offspring to cardiometabolic disorders in a sex-specific manner.

    In utero exposure to air pollution predisposed rabbit offspring to cardiometabolic disorders in a sex-specific manner.

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