• Poole Corcoran posted an update 6 months, 1 week ago

    The coracoclavicular fixation with suture anchors adds stability to type IIb distal clavicle fractures fixed with a plate and screws when loaded to failure. The purpose of this study was to compare the clinical and radiological outcomes between the use of a locking compression plate (LCP) with all-suture anchor fixation and hook LCP fixation of Neer IIb distal clavicle fractures.

    A total of 82 consecutive patients who underwent plate fixation for Neer IIb distal clavicle fractures were included. The subjects were divided into two groups an LCP with all-suture anchor fixation group and hook LCP fixation group. For clinical assessments, the American Shoulder and Elbow Surgeons score, Korean shoulder score (KSS), and Constant score were recorded. A percentage of the coracoclavicular distance (CCD%) was used to evaluate fracture reduction. Typical reported complications, such as secondary dislocation, implant failure or loosening, peri-implant fracture, acromion osteolysis, stiffness, peri-anchor osteolysis, patients or patients with underlying diseases.

    Level III, retrospective study.

    Level III, retrospective study.It is unclear whether task representation generated in imagery simulates performance demands in reacting to stimuli. This study investigated whether perceptual and motor control processes used to react to unpredictable stimuli and initiate an ipsilateral movement were replicated during imagery. Fifty-nine undergraduate students (Mage = 27.01 years, SD = 8.30) completed 30 simple, two-choice congruent and two-choice incongruent ipsilateral finger-foot movement trials in response to a physically presented or imagined stimulus. The results appear to indicate that participants were reacting to imagined and actual stimuli, as the ipsilateral finger-foot programming rule was maintained and reaction time initially slowed as task difficulty increased. These findings support theoretical similarities between imagery and physical performance of reaction tasks, with imagers generating and reacting to unpredictable stimuli. Slower imagery performance than physical performance on the two-choice incongruent task may indicate that task complexity is limited during imagery. Variation in results between the imagery and physical conditions potentially supports that imagers were able to react to the imagined stimulus. However, exploratory processes used to react to stimuli were not replicated during imagery. The present findings have potentially significant implications for the functional and applied use of imagery for skill acquisition.A life-threatening disease such as breast cancer with its pervasive nature of uncertainty can lead to feelings of disempowerment. Nonetheless, survivors may reconstruct their identity within optimism and a celebration of a new self. In this qualitative constructionist study, we explored survivors’ experiences, meaning-making, and identity transformation. Semi-structured interviews were undertaken with 11 women who identified as breast cancer survivors. Participants were aged 35 years old or above and were in post-diagnosis for at least 3 years. Interview data were collected and analyzed using thematic techniques. We identified three master themes Diseased Self, focused on emotional distress and the presentation of a façade; Coping Self, explored resilience and post-traumatic growth; and Transformed Self, engaged in presentations of self-image, meaning-making, and psychological ownership addressing survivorship and empowerment. The findings may be used to inform guidelines and support for cancer survivors considering the impact of diagnosis, treatment, and post-treatment experiences on self-identity.Police officers are typically the first responders when victims of intimate partner violence (IPV) report abuse. Therefore, police officers’ attitudes toward IPV and victim blaming are crucial. This study aimed to observe how police officers’ sexist attitudes affect their perspectives on IPV and their victim-blaming attitudes, depending on the gender role exhibited by the victim. The Ambivalent Sexism Inventory was used to classify 139 Thai male police officers into four groups of sexism hostile sexist, benevolent sexist, ambivalent sexist, and nonsexist. Then, the participants were randomly assigned to watch a simulation video, in which a victim of IPV filed a report after being abused by her husband. There were two versions of the video, one in which the victim played a traditional gender role and the other a nontraditional role. Multivariate analysis of variance was employed for data analysis. The results demonstrated statistically significant effects of ambivalent sexism and victim’s gender role on attitudes toward IPV and victim blaming. This study contributes to the growing body of research on police officers’ performances in the context of IPV in Thailand and contributes to existing scholarship. It provides Thai police precincts with information that can equip them to develop new sensitivity training programs and can help legislators improve the effectiveness of victim protection acts.Despite increasing interest in pharmacogenomics, and the potential benefits to improve patient care, implementation into clinical practice has not been widespread. Recently, there has been a drive to implement genomic medicine into the UK National Health Service (NHS), largely spurred on by the success of the 100,000 Genomes Project. The UK Pharmacogenetics and Stratified Medicine Network, NHS England and Genomics England invited experts from academia, the healthcare sector, industry and patient representatives to come together to discuss the opportunities and challenges of implementing pharmacogenomics into the NHS. This report highlights the discussions of the workshop to provide an overview of the issues that need to be considered to enable pharmacogenomic medicine to become mainstream within the NHS.

    Detecting marijuana use is a component of most urine drug screens targeting a single Δ

    -tetrahydrocannabinol metabolite. Recently, the non-intoxicating cannabinoid, cannabidiol (CBD), has gained popular acceptance for a myriad of reasons. Commercially available CBD products sold without purity regulations have become ubiquitous. Many products contain trace tetrahydrocannabinol. Long-term or high dose use of CBD products can result in tetrahydrocannabinol exposures, potentially producing a positive marijuana drug test. These results are not false positives since marijuana biomarkers are present, but inaccurately identify donors as marijuana users. Salinosporamide A Addressing this conundrum, we developed an assay discriminating marijuana use from the use of CBD contaminated with tetrahydrocannabinol.

    Following the synthesis of a primary CBD metabolite, a LC-MS/MS assay was developed measuring the urinary metabolites tetrahydrocannabinol, 11-nor-carboxy-Δ

    -tetrahydrocannabinol, CBD, and 7-carboxy-cannabidiol. The assay was utilized on 425 patients claiming CBD use, and sixteen samples from trusted users of commercial CBD products.

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