Rossen Moesgaard

Rationale The circadian clock coordinates cell proliferation and metabolism and impacts the progression of some diseases, particularly cancer. Pharmacological modulation of the circadian machinery may be an effective therapeutic approach for treating cancer. SR9009 is a specific synthetic agonist of the REV-ERBs, essential circadian clock…[Read more]

Results This review found much evidence for the use of inorganic nanoparticles for PTT-based combinational cancer therapy. Conclusion Under synergistic effects, inorganic nanomaterial-based combinational treatments exhibit enhanced therapeutic effects compared to PTT, CHT, RT, IT or PDT alone and should be further investigated in the cancer field.…[Read more]

These insights have led to a new model for the disorder-to-order transition in IDPs termed ‘templated folding’, whereby the binding partner dictates distinct structural transitions en route to product, while ensuring a co-operative folding. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.The global…[Read more]

Aim To investigate the expression and prognostic value of KRT 15 in esophageal carcinoma. Materials & methods The expression levels of KRT 15 were measured in 128 cases of esophageal carcinoma and matched adjacent normal tissues by immunohistochemistry and Western blot assays. Results & conclusion Western blot analysis shown the expression levels…[Read more]

The article presents the results of long-term field tests and their mathematical analysis regarding the impacts of innovative phase change materials on the energy efficiency of composite windows with various glazing parameters. Research was conducted on six glazing combinations throughout the heating season in a temperate climate in Rzeszów…[Read more]

We further combined IF analyses with microfluorimetric Ca2+ measurements to address the functionality of these ion channels in iDNs. Thus, we provide a detailed morphological and functional characterization of iDNs, thereby, underpinning their enormous potential as an animal-free alternative for human specific research in the pain field for…[Read more]

BACKGROUND Age-related changes in cardiac morphology and function have not been unknown in the elderly. The Japanese eLderly data Of Normal echocardioGraphy (J-LONG) study is a prospective multicenter cohort study and aimed to investigate the echocardiographic data in the healthy Japanese elderly. METHODS Thirty domestic facilities participated in…[Read more]

BACKGROUND The inflammatory response plays a critical role in coronavirus disease 2019 (COVID-19), and inflammatory cytokine storm increases the severity of COVID-19. OBJECTIVE To investigate the ability of interleukin-6 (IL-6), C-reactive protein (CRP), and procalcitonin (PCT) to predict mild and severe cases of COVID-19. STUDY DESIGN This…[Read more]