• The shell structure and release properties of layer-by-layer assembled particles could be tailored by controlling the interactions between starches.Although research on phytochemicals has been a hot topic due to positive effects on human health, modification of starch with phytochemicals has been limited. In the present work, cassava…[Read more]

  • Slot Meier posted an update 6 months ago

    diographic screening in combination with secondary antibiotic prophylaxis in children with evidence of latent rheumatic heart disease may be an effective strategy to reduce the prevalence of definite or borderline rheumatic heart disease in endemic regions.

    ClinicalTrials.gov Identifier NCT01550068.

    ClinicalTrials.gov Identifier…[Read more]

  • Slot Meier posted an update 6 months ago

    These results indicate that AEOL11207 and AEOL11114 are orally active metalloporphyrins and protect against 6-OHDA neurotoxicity 1-3 days postlesioning, suggesting disease-modifying properties and translational potential for PD. SIGNIFICANCE STATEMENT Two catalytic antioxidants showed gastrointestinal absorption, achieved high plasma…[Read more]

  • Slot Meier posted an update 6 months ago

    The KCNA1 gene encodes the α subunit of the voltage-gated Kv1.1 potassium channel that critically regulates neuronal excitability in the central and peripheral nervous systems. Mutations in KCNA1 have been classically associated with episodic ataxia type 1 (EA1), a movement disorder triggered by physical and emotional stress. Additional features…[Read more]

  • Slot Meier posted an update 6 months ago

    Taken together, the current results indicate that flavopereirine exhibits good anticancer activity in HCC cells.

    Forkhead box O4 (FOXO4) has been demonstrated to be a tumor suppressor and proposed as target for treatment of a variety of cancer types. However, the role of FOXO4 in cholangiocarcinoma (CCA), a dangerous cancer of bile-duct…[Read more]

  • Slot Meier posted an update 6 months ago

    Most antibiotic prescribing occurs in primary care. learn more Even within the same health facility, there may be differences between prescribers in their tendency to prescribe antibiotics, which may be masked by summary data. We aimed to quantify prescriber variability in antibiotic prescription to patients with acute fever in primary care…[Read more]

  • Slot Meier posted an update 6 months, 1 week ago

    The proposed method significantly improves the quality of waveforms compared to the input CHROM signals, with the mean absolute error of AVNN (the average of all normal-to-normal intervals) reduced by 41.19%, 40.45%, 41.63%, and the mean absolute error of SDNN (the standard deviation of all NN intervals) reduced by 37.53%, 44.29%, 58.41%, in the…[Read more]

  • Slot Meier posted an update 6 months, 1 week ago

    Study of the potential of Antarctic microorganisms for use in bioremediation is of increasing interest due to their adaptations to harsh environmental conditions and their metabolic potential in removing a wide variety of organic pollutants at low temperature. In this study, the psychrotolerant bacterium Rhodococcus sp. strain AQ5-07, originally…[Read more]

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