• 6 calls per month. The average length of time spent on a call was 21 minutes. For 30% of calls, families had tried contacting their PCPs first, and 55% of calls occurred at night. Topics of calls included requesting advice about symptoms, time line for reevaluation, and assistance with medications.

    This safety net provided families with…[Read more]

  • The energies of these bonds are in the 5.40(3) kJ mol-1 ≤ Ea ≤ 5.70(5) kJ mol-1 range.Alternative transcript cleavage and polyadenylation is linked to cancer cell transformation, proliferation and outcome. This has led researchers to develop methods to detect and bioinformatically analyse alternative polyadenylation as potential cancer bio…[Read more]

  • Histopathologic diagnosis was glioblastoma in 17 patients (68%) and lower-grade tumor in eight patients. In 3 out of 12 patients of which a paraffin block could be retrieved immunohistochemistry revealed an

    -mutant glioma. Most frequent EDM locations were bone/bone marrow (14/25 patients; 56%), and lymph nodes (6/25 patients; 24%).…[Read more]

  • The type 2 secretion system (T2SS) is present in some Gram-negative eubacteria and used to secrete proteins across the outer membrane. Here we report that certain representative heteroloboseans, jakobids, malawimonads and hemimastigotes unexpectedly possess homologues of core T2SS components. We show that at least some of them are present in…[Read more]

  • We conclude that serum circulating microRNA-30d is a sensitive biomarker for Ang II-induced cardiovascular complications. learn more It is also postulated that Ang II-induced cardiomyocyte hypertrophy could be independent of miR-30d/BNP signaling pathways.

    Radiotherapy represents an effective treatment option in Graves’ ophthalmopathy (GO),…[Read more]

  • The recent randomized controlled phase III CLEAR trial results are the last to complement immune checkpoint inhibitor (ICI)-based doublet combination therapies for treatment-naïve metastatic clear-cell renal cell carcinoma. The CLEAR trial demonstrated an improved progression-free survival (PFS), overall survival (OS), and an objective response…[Read more]

  • Among these horses, four were found seropositive for all four infections. On the other hand, all the tested horses were seronegative for equine viral arteritis (EVA), Eastern equine encephalomyelitis (EEE), Venezuelan equine encephalitis (VEE), Western equine encephalomyelitis (WEE) and glanders. The data from this survey conducted on a small…[Read more]

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